- Absence of common activating mutations of the epidermal growth factor receptor gene in thyroid cancers from American and Japanese patients
[作者：Ricarte, JC; Matsuse, M; Lau, C; Ryder, M; Nishihara, E; Ghossein, RA; Ladanyi, M; Yamashita, S; Mitsutake, N; Fagin, JA,期刊：International Journal of Cancer, 页码：2464-2473 , 文章类型： Letter，,卷期：2012年130-9]
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- Role of SOCS1 in tumor progression and therapeutic application
[作者：Zhang, J; Li, H; Yu, JP; Wang, SE; Ren, XB,期刊：International Journal of Cancer, 页码：1971-1980 , 文章类型： Review，,卷期：2012年130-9]
- SOCS1, a prototype molecule of the SOCS family, was initially defined as a suppressor of cytokine signaling. The molecular mechanisms of SOCS1-mediated functions have been subsequently identified by studies using gene kn...
- The protective role of polymorphism MKK4-1304 T > G in nasopharyngeal carcinoma is modulated by Epstein-Barr virus' infection status
[作者：Zheng, J; Liu, B; Zhang, LY; Jiang, L; Huang, BF; You, YH; Jiang, QP; Zhang, SX; Lu, JC; Zhou, YF,期刊：International Journal of Cancer, 页码：1981-1990 , 文章类型： Article，,卷期：2012年130-9]
- MKK4 is a candidate tumor suppressor, which acts as a critical mediator of EpsteinBarr Virus (EBV)-induced c-Jun N-terminal kinase (JNK) activation. Functional polymorphism MKK4 -1304T>G has been showed to be protective ...
- MAGE-D4B is a novel marker of poor prognosis and potential therapeutic target involved in breast cancer tumorigenesis
[作者：Germano, S; Kennedy, S; Rani, S; Gleeson, G; Clynes, M; Doolan, P; McDonnell, S; Hughes, L; Crown, J; O'Driscoll, L,期刊：International Journal of Cancer, 页码：1991-2002 , 文章类型： Article，,卷期：2012年130-9]
- Melanoma-associated antigen (MAGE) family members are generally described as tumor-specific antigens. An association between MAGE-D4B and breast cancer has yet to be reported and the functional role of the encoded protei...
- IGF binding protein-6 expression in vascular endothelial cells is induced by hypoxia and plays a negative role in tumor angiogenesis
[作者：Zhang, CY; Lu, L; Li, Y; Wang, XL; Zhou, JF; Liu, YZ; Fu, P; Gallicchio, MA; Bach, LA; Duan, CM,期刊：International Journal of Cancer, 页码：2003-2012 , 文章类型： Article，,卷期：2012年130-9]
- Hypoxia stimulates tumor angiogenesis by inducing the expression of angiogenic molecules. The negative regulators of this process, however, are not well understood. Here, we report that hypoxia induced the expression of ...
- Overexpression of NaV1.6 channels is associated with the invasion capacity of human cervical cancer
[作者：Hernandez-Plata, E; Ortiz, CS; Marquina-Castillo, B; Medina-Martinez, I; Alfaro, A; Berumen, J; Rivera, M; Gomora, JC,期刊：International Journal of Cancer, 页码：2013-2023 , 文章类型： Article，,卷期：2012年130-9]
- Functional activity of voltage-gated sodium channels (VGSC) has been associated to the invasion and metastasis behaviors of prostate, breast and some other types of cancer. We previously reported the functional expressio...
- Role of exosomes released by chronic myelogenous leukemia cells in angiogenesis
[作者：Taverna, S; Flugy, A; Saieva, L; Kohn, EC; Santoro, A; Meraviglia, S; De Leo, G; Alessandro, R,期刊：International Journal of Cancer, 页码：2033-2043 , 文章类型： Article，,卷期：2012年130-9]
- Our study is designed to assess if exosomes released from chronic myelogenous leukemia (CML) cells may modulate angiogenesis. We have isolated and characterized the exosomes generated from LAMA84 CML cells and demonstrat...
- MicroRNA-30a inhibits epithelial-to-mesenchymal transition by targeting Snai1 and is downregulated in non-small cell lung cancer
[作者：Kumarswamy, R; Mudduluru, G; Ceppi, P; Muppala, S; Kozlowski, M; Niklinski, J; Papotti, M; Allgayer, H,期刊：International Journal of Cancer, 页码：2044-2053 , 文章类型： Article，,卷期：2012年130-9]
- MicroRNAs (miRNAs) are small non-coding RNAs which regulate gene expression by base-pairing to the 3'-UTR of the target mRNA. Recently, miRNAs have been shown to regulate cancer metastasis, however, central molecular mec...
- MDM2 promoter SNP309 is associated with an increased susceptibility to chronic lymphocytic leukemia and correlates with MDM2 mRNA expression in Chinese patients with CLL
[作者：Dong, HJ; Fang, C; Fan, L; Zhu, DX; Wang, DM; Zhu, HY; Zhuang, Y; Miao, KR; Liu, P; Xu, W; Li, JY,期刊：International Journal of Cancer, 页码：2054-2061 , 文章类型： Article，,卷期：2012年130-9]
- A single nucleotide polymorphism (SNP) at position 309 in the promoter region of MDM2 leading to increased expression of MDM2 and attenuated function of p53 has recently been suggested as an unfavorable prognostic marker...
- Genetic variants in DNA repair genes and the risk of cutaneous malignant melanoma in melanoma-prone families with/without CDKN2A mutations
[作者：Liang, XS; Pfeiffer, RM; Wheeler, W; Maeder, D; Burdette, L; Yeager, M; Chanock, S; Tucker, MA; Goldstein, AM; Yang, XHR,期刊：International Journal of Cancer, 页码：2062-2066 , 文章类型： Article，,卷期：2012年130-9]
- Cutaneous malignant melanoma (CMM) is an etiologically heterogeneous disease with genetic, environmental (sun exposure) and host (pigmentation/nevi) factors and their interactions contributing to risk. Genetic variants i...
- alpha(L)beta(2) Integrin is indispensable for CD8(+) T-cell recruitment in experimental pancreatic and hepatocellular cancer
[作者：Takeichi, T; Mocevicius, P; Deduchovas, O; Salnikova, O; Castro-Santa, E; Buchler, MW; Schmidt, J; Ryschich, E,期刊：International Journal of Cancer, 页码：2067-2076 , 文章类型： Article，,卷期：2012年130-9]
- Recruitment of activated leukocytes from peripheral blood into the tumor tissue is a crucial step of the immune response, which is controlled by the interaction between specific adhesion molecules such as endothelial ICA...
- Candidate microRNA biomarkers in human colorectal cancer: Systematic review profiling studies and experimental validation
[作者：Ma, YL; Zhang, P; Yang, JJ; Liu, ZH; Yang, Z; Qin, HL,期刊：International Journal of Cancer, 页码：2077-2087 , 文章类型： Article，,卷期：2012年130-9]
- Colorectal cancer (CRC) is a major cause of cancer mortality worldwide. There is an urgent need to search for specific and sensitive biomarkers for early diagnosis of CRC. We carried out a comprehensive systematic review...
- An American founder mutation in MLH1
[作者：Tomsic, J; Liyanarachchi, S; Hampel, H; Morak, M; Thomas, BC; Raymond, VM; Chittenden, A; Schackert, HK; Gruber, SB; Syngal, S; Viel, A; Holinski-Feder, E; Thibodeau, SN; de la Chapelle, A,期刊：International Journal of Cancer, 页码：2088-2095 , 文章类型： Article，,卷期：2012年130-9]
- Mutations in the mismatch repair genes cause Lynch syndrome (LS), conferring high risk of colorectal, endometrial and some other cancers. After the same splice site mutation in the MLH1 gene (c.589-2A>G) had been observe...
- Uptake of faecal immunochemical test screening among nonparticipants in a flexible sigmoidoscopy screening programme
[作者：Hol, L; Kuipers, EJ; van Ballegooijen, M; van Vuuren, AJ; Reijerink, JCIY; Habbema, DJF; van Leerdam, ME,期刊：International Journal of Cancer, 页码：2096-2102 , 文章类型： Article，,卷期：2012年130-9]
- Screening programmes based on single modality testing may prevent individuals with a preference for a different test from participating. We conducted a population-based trial to determine whether nonparticipants in flexi...
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