- Mouse Models of Colon Cancer
[作者:Taketo, MM; Edelmann, W,期刊:Gastroenterology, 页码:780-798 , 文章类型: Review,,卷期:2009年136-3]
- Genetically engineered mice are essential tools in both mechanistic studies and drug development in colon cancer research. Mice with mutations in the Apc gene, as well as in genes that modify or interact with Apc, are im...
- The Recurrence of Acute Alcohol-Associated Pancreatitis Can Be Reduced: A Randomized Controlled Trial
[作者:Nordback, I; Pelli, H; Lappalainen-Lehto, R; Jarvinen, S; Raty, S; Sand, J,期刊:Gastroenterology, 页码:848-855 , 文章类型: Article,,卷期:2009年136-3]
- Background & Aims: In the long term, half of patients with their first alcohol-associated acute pancreatitis (AP) develop acute recurrence, alcohol consumption being the main risk factor. None of the recent national or i...
- Tube Feeding Improves Intestinal Absorption in Short Bowel Syndrome Patients
[作者:Joly, F; Dray, X; Corcos, O; Barbot, L; Kapel, N; Messing, B,期刊:Gastroenterology, 页码:824-831 , 文章类型: Article,,卷期:2009年136-3]
- Background & Aims: Tube feeding, recommended for patients with short bowel syndrome in only the postoperative period, has not been compared with oral feeding for absorption. We studied whether tube feeding increased abso...
- Alcohol Types and Sociodemographic Characteristics as Risk Factors for Barrett's Esophagus
[作者:Kubo, A; Levin, TR; Block, G; Rumore, GJ; Quesenberry, CP; Buffler, P; Corley, DA,期刊:Gastroenterology, 页码:806-815 , 文章类型: Article,,卷期:2009年136-3]
- Background & Aims: Little is known about the effects of alcohol use and sociodemographics on the risk of Barrett's esophagus, a precursor to esophageal adenocarcinoma. We evaluated the association between alcohol use, al...
- Invariant Natural Killer T Cells Suppress the Neutrophil Inflammatory Response in a Mouse Model of Cholestatic Liver Damage
[作者:Wintermeyer, P; Cheng, CW; Gehring, S; Hoffman, BL; Holub, M; Brossay, L; Gregory, SH,期刊:Gastroenterology, 页码:1048-1059 , 文章类型: Article,,卷期:2009年136-3]
- Background & Aims: NK1.1(+) TCR alpha beta(int) CD1-restricted T (NKT) cells are a unique subset of T lymphocytes that are believed to have an immunoregulatory role in a wide range of diseases. Most mouse NKT cells expre...
- Low Cerebral Oxygen Consumption and Blood Flow in Patients With Cirrhosis and an Acute Episode of Hepatic Encephalopathy
[作者:Iversen, P; Sorensen, M; Bak, LK; Waagepetersen, HS; Vafaee, MS; Borghammer, P; Mouridsen, K; Jensen, SB; Vilstrup, H; Schousboe, A; Ott, P; Gjedde, A; Keiding, S,期刊:Gastroenterology, 页码:863-871 , 文章类型: Article,,卷期:2009年136-3]
- Background & Aims: It is unclear whether patients with hepatic encephalopathy (HE) have disturbed brain oxygen metabolism and blood flow. Methods: We measured cerebral oxygen metabolism rate (CMRO2) by using O-15-oxygen ...
- A Fast-Track Program Reduces Complications and Length of Hospital Stay After Open Colonic Surgery
[作者:Muller, S; Zalunardo, MP; Hubner, M; Clavien, PA; Demartines, N,期刊:Gastroenterology, 页码:842-847 , 文章类型: Article,,卷期:2009年136-3]
- Background & Aims: A fast-track program is a multimodal approach for patients undergoing colonic surgery that combines stringent regimens of perioperative care (fluid restriction, optimized analgesia, forced mobilization...
- ATP8B1 Deficiency Disrupts the Bile Canalicular Membrane Bilayer Structure in Hepatocytes, But FXR Expression and Activity Are Maintained
[作者:Cai, SY; Gautam, S; Nguyen, T; Soroka, CJ; Rahner, C; Boyer, JL,期刊:Gastroenterology, 页码:1060-1069 , 文章类型: Article,,卷期:2009年136-3]
- Background & Aims: Progressive familial intrahepatic cholestasis 1 (PFIC1) results from mutations in ATP8B1, a putative aminophospholipid flippase. Conflicting hypotheses have been proposed for the pathogenesis of PFIC1....
- EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features
[作者:Yamashita, T; Ji, JF; Budhu, A; Forgues, M; Yang, W; Wang, HY; Jia, HL; Ye, QH; Qin, LX; Wauthier, E; Reid, LM; Minato, H; Honda, M; Kaneko, S; Tang, ZY; Wang, XW,期刊:Gastroenterology, 页码:1012-1024 , 文章类型: Article,,卷期:2009年136-3]
- Background & Aims: Cancer progression/metastases and embryonic development share many properties including cellular plasticity, dynamic cell motility, and integral interaction with the microenvironment. We hypothesized t...
- Improved Virologic Response in Chronic Hepatitis C Genotype 4 Treated With Nitazoxanide, Peginterferon, and Ribavirin
[作者:Rossignol, JF; Elfert, A; El-Gohary, Y; Keeffe, EB,期刊:Gastroenterology, 页码:856-862 , 文章类型: Article,,卷期:2009年136-3]
- Background & Aims: Sustained virologic response (SVR) rates of 50%-60% have been achieved in patients with chronic hepatitis C genotype 4 treated with peginterferon plus ribavirin. The safety and efficacy of nitazoxanide...
- A Pooled Analysis of Advanced Colorectal Neoplasia Diagnoses After Colonoscopic Polypectomy
[作者:Martinez, ME; Baron, JA; Lieberman, DA; Schatzkin, A; Lanza, E; Winawer, SJ; Zauber, AG; Jiang, RY; Ahnen, DJ; Bond, JH; Church, TR; Robertson, DJ; Smith-Warner, SA; Jacobs, ET; Alberts, DS; Greenberg, ER,期刊:Gastroenterology, 页码:832-841 , 文章类型: Article,,卷期:2009年136-3]
- Background & Aims: Limited data exist regarding the actual risk of developing advanced adenomas and cancer after polypectomy or the factors that determine risk. Methods: We pooled individual data from 8 prospective studi...
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