- Regulation of gene transcription by the oncoprotein MYC
[作者:Luscher, B; Vervoorts, J,期刊:Gene, 页码:145-160 , 文章类型: Review,,卷期:2012年494-2]
- The proteins of the MYC/MAX/MAD network are central regulators of many key processes associated with basic cell physiology. These include the regulation of protein biosynthesis, energy metabolism, proliferation, and apop...
- Identification of a novel isoform of DHRS4 protein with a nuclear localization signal
[作者:Su, ZJ; Li, R; Song, XH; Liu, GF; Li, YF; Chang, XL; Li, CZ; Huang, DY,期刊:Gene, 页码:161-167 , 文章类型: Article,,卷期:2012年494-2]
- The DHRS4 gene encodes an NADP(H)-dependent retinol dehydrogenase/reductase (NRDR) and plays an important role in regulating the synthesis of retinoic acid. In the present study, we identified a novel splice RNA variant,...
- Association study of microRNA polymorphisms with risk of idiopathic recurrent spontaneous abortion in Korean women
[作者:Jeon, YJ; Choi, YS; Rah, H; Kim, SY; Choi, DH; Cha, SH; Shin, JE; Shim, SH; Lee, WS; Kim, NK,期刊:Gene, 页码:168-173 , 文章类型: Article,,卷期:2012年494-2]
- Aim: The aim of this study was to investigate the association of microRNA polymorphisms (miR-146aC>G, miR-149T>C, miR-196a2T>C, and miR-499A>G) in Korean patients with recurrent spontaneous abortion (RSA). Methods: We co...
- Cloning and characterization of homeologous cellulose synthase catalytic subunit 2 genes from allotetraploid cotton (Gossypium hirsutum L.)
[作者:Kim, HJ; Triplett, BA; Zhang, HB; Lee, MK; Hinchliffe, DJ; Li, P; Fang, DD,期刊:Gene, 页码:181-189 , 文章类型: Article,,卷期:2012年494-2]
- Cellulose synthase catalytic subunits (CesAs) are the catalytic sites within a multisubunit complex for cellulose biosynthesis in plants. CesAs have been extensively studied in diploid plants, but are not well characteri...
- Significant associations of the rs2943634 (2q36.3) genetic polymorphism with adiponectin, high density lipoprotein cholesterol and ischemic stroke
[作者:Arregui, M; Fisher, E; Knuppel, S; Buijsse, B; di Giuseppe, R; Fritsche, A; Corella, D; Willich, SN; Boeing, H; Weikert, C,期刊:Gene, 页码:190-195 , 文章类型: Article,,卷期:2012年494-2]
- Background: rs2943634 C/A single nucleotide polymorphism (SNP), located in a non coding region of chromosome 2q36.3, has been associated with coronary artery disease in two genome wide association studies. Our goal was t...
- Transcriptional analysis of the Aurora inhibitor Danusertib leading to biomarker identification in TP53 wild type cells
[作者:Bosotti, R; Carpinelli, P; Healy, S; Locatelli, G; Cappella, P; Lanfrancone, L; Calogero, R; Moll, J; Isacchi, A,期刊:Gene, 页码:202-208 , 文章类型: Article,,卷期:2012年494-2]
- Aurora kinases represent an appealing target for anticancer therapies and several Aurora inhibitors are in clinical development, including the potent pan-Aurora inhibitor Danusertib. Treatment with Aurora inhibitors has ...
- The complete mitochondrial genome of Gomphocerus tibetanus Uvarov, 1935 (Orthoptera: Acrididae: Gomphocerinae)
[作者:Yin, H; Zhi, YC; Jiang, HD; Wang, PX; Yin, XC; Zhang, DC,期刊:Gene, 页码:214-218 , 文章类型: Article,,卷期:2012年494-2]
- The complete nucleotide sequence of the mitochondrial genome (mitogenome) of Gomphocerus tibetanus Uvarov, 1935 (Orthoptera: Acrididae: Gomphocerinae) was determined. It is 15,571 bp in length and contains 74.8% A + T. A...
- Improved method for the isolation of RNA from bacteria refractory to disruption, including S. aureus producing biofilm
[作者:Atshan, SS; Shamsudin, MN; Lung, LTT; Ling, KH; Sekawi, Z; Pei, CP; Ghaznavi-Rad, E,期刊:Gene, 页码:219-224 , 文章类型: Article,,卷期:2012年494-2]
- The development of fast, reliable and inexpensive phenol protocol is described for the isolation of RNA from bacterial biofilm producers. The method was tested on Staphylococcus aureus (S. aureus) and other biofilm-produ...
- Molecular cloning and characterization of the sheep alpha-TTP gene and its expression in response to different vitamin E status
[作者:Liu, K; Luo, HL; Yue, DB; Ge, SY; Yuan, F; Yan, LY; Jia, HN,期刊:Gene, 页码:225-230 , 文章类型: Article,,卷期:2012年494-2]
- The alpha-tocopherol transfer protein (a-TIP) is a similar to 32 kDa protein that exhibits a marked ligand specificity and selectively recognizes of alpha-tocopherol, which is the most active form of vitamin E. The alpha...
- Antisense oligonucleotide corrects splice abnormality in hereditary myopathy with lactic acidosis
[作者:Sanaker, PS; Toompuu, M; McClorey, G; Bindoff, LA,期刊:Gene, 页码:231-236 , 文章类型: Article,,卷期:2012年494-2]
- Hereditary myopathy with lactic acidosis (HML) (OMIM #255125) presents in childhood with exercise intolerance and muscle pain on trivial exercise, lactic acidosis, dyspnoea, palpitations, and rhabdomyolysis which can be ...
- Association of myostatin gene polymorphisms with obesity in Chinese north Han human subjects
[作者:Pan, H; Ping, XC; Zhu, HJ; Gong, FY; Dong, CX; Li, NS; Wang, LJ; Yang, HB,期刊:Gene, 页码:237-241 , 文章类型: Article,,卷期:2012年494-2]
- Context: Myostatin (MSTN) is a member of the TGF-beta superfamily of signal transduction proteins, which plays an important role in muscular growth and lipid metabolism. Objective: To study the association of myostatin g...
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