- p38 maintains E-cadherin expression by modulating TAK1-NF-kappa B during epithelial-to-mesenchymal transition
[作者:Strippoli, R; Benedicto, I; Foronda, M; Perez-Lozano, ML; Sanchez-Perales, S; Lopez-Cabrera, M; del Pozo, MA,期刊:Journal of cell science, 页码:4321-4331 , 文章类型: Article,,卷期:2010年123-24]
- Epithelial-to-mesenchymal transition (EMT) of peritoneal mesothelial cells is a pathological process that occurs during peritoneal dialysis. EMT leads to peritoneal fibrosis, ultrafiltration failure and eventually to the...
- RAGE-TXNIP axis is required for S100B-promoted Schwann cell migration, fibronectin expression and cytokine secretion
[作者:Sbai, O; Devi, TS; Melone, MAB; Feron, F; Khrestchatisky, M; Singh, LP; Perrone, L,期刊:Journal of cell science, 页码:4332-4339 , 文章类型: Article,,卷期:2010年123-24]
- During peripheral nerve injury, Schwann cells (SCs) adopt a migratory phenotype and remodel the extracellular matrix and provide a supportive activity for neuron regeneration. SCs synthesize neurotrophic factors and cyto...
- Shared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members
[作者:Hong, JY; Park, JI; Cho, K; Gu, DM; Ji, H; Artandi, SE; McCrea, PD,期刊:Journal of cell science, 页码:4351-4365 , 文章类型: Article,,卷期:2010年123-24]
- Wnt signaling pathways have fundamental roles in animal development and tumor progression. Here, employing Xenopus embryos and mammalian cell lines, we report that the degradation machinery of the canonical Wnt pathway m...
- Mid1p-dependent regulation of the M-G1 transcription wave in fission yeast
[作者:Agarwal, M; Papadopoulou, K; Mayeux, A; Vajrala, V; Quintana, DM; Paoletti, A; McInerny, CJ,期刊:Journal of cell science, 页码:4366-4373 , 文章类型: Article,,卷期:2010年123-24]
- The control of gene expression at certain times during the mitotic cell division cycle is a common feature in eukaryotes. In fission yeast, at least five waves of gene expression have been described, with one transcribed...
- Regulation of cell cycle-specific gene expression in fission yeast by the Cdc14p-like phosphatase Clp1p
[作者:Papadopoulou, K; Chen, JS; Mead, E; Feoktistova, A; Petit, C; Agarwal, M; Jamal, M; Malik, A; Spanos, A; Sedgwick, SG; Karagiannis, J; Balasubramanian, MK; Gould, KL; McInerny, CJ,期刊:Journal of cell science, 页码:4374-4381 , 文章类型: Article,,卷期:2010年123-24]
- Regulated gene expression makes an important contribution to cell cycle control mechanisms. In fission yeast, a group of genes is coordinately expressed during a late stage of the cell cycle (M phase and cytokinesis) tha...
- CEACAM1: a key regulator of vascular permeability
[作者:Nouvion, AL; Oubaha, M; LeBlanc, S; Davis, EC; Jastrow, H; Kammerer, R; Breton, V; Turbide, C; Ergun, S; Gratton, JP; Beauchemin, N,期刊:Journal of cell science, 页码:4221-4230 , 文章类型: Article,,卷期:2010年123-24]
- Carcinoembryonic antigen cell adhesion molecule-1 (CEACAM1) is an immunoglobulin-like cell surface co-receptor expressed on epithelial, hematopoietic and endothelial cells. CEACAM1 functions as an adhesion molecule, main...
- IKK alpha controls canonical TGF beta-SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in Panc1 cells
[作者:Brandl, M; Seidler, B; Haller, F; Adamski, J; Schmid, RM; Saur, D; Schneider, G,期刊:Journal of cell science, 页码:4231-4239 , 文章类型: Article,,卷期:2010年123-24]
- The epithelial to mesenchymal transition (EMT) is a crucial step in tumor progression, and the TGF beta-SMAD signaling pathway is an inductor of EMT in many tumor types. One hallmark of EMT is downregulation of the adher...
- PI3KC2 alpha, a class II PI3K, is required for dynamin-independent internalization pathways
[作者:Krag, C; Malmberg, EK; Salcini, AE,期刊:Journal of cell science, 页码:4240-4250 , 文章类型: Article,,卷期:2010年123-24]
- Increasing evidence indicates that cellular uptake of several molecules can occur independently of functional dynamin, but the molecular players that regulate dynamin-independent endocytosis and the subsequent traffickin...
- SIRT2 regulates NF-kappa B-dependent gene expression through deacetylation of p65 Lys310
[作者:Rothgiesser, KM; Erener, S; Waibel, S; Luscher, B; Hottiger, MO,期刊:Journal of cell science, 页码:4251-4258 , 文章类型: Article,,卷期:2010年123-24]
- NF-kappa B regulates the expression of a large number of target genes involved in the immune and inflammatory response, apoptosis, cell proliferation, differentiation and survival. In this study, we identified SIRT2 as a...
- Serine 363 of the delta-opioid receptor is crucial for adopting distinct pathways to activate ERK1/2 in response to stimulation with different ligands
[作者:Xu, C; Hong, MH; Zhang, LS; Hou, YY; Wang, YH; Wang, FF; Chen, YJ; Xu, XJ; Chen, J; Xie, X; Ma, L; Chi, ZQ; Liu, JG,期刊:Journal of cell science, 页码:4259-4270 , 文章类型: Article,,卷期:2010年123-24]
- Distinct opioid receptor agonists have been proved to induce differential patterns of ERK activation, but the underlying mechanisms remain unclear. Here, we report that Ser363 in the delta-opioid receptor (delta OR) dete...
- The transporter associated with antigen processing (TAP) is active in a post-ER compartment
[作者:Ghanem, E; Fritzsche, S; Al-Balushi, M; Hashem, J; Ghuneim, L; Thomer, L; Kalbacher, H; van Endert, P; Wiertz, E; Tampe, R; Springer, S,期刊:Journal of cell science, 页码:4271-4279 , 文章类型: Article,,卷期:2010年123-24]
- The translocation of cytosolic peptides into the lumen of the endoplasmic reticulum (ER) is a crucial step in the presentation of intracellular antigen to T cells by major histocompatibility complex (MHC) class I molecul...
- Caveolin limits membrane microdomain mobility and integrin-mediated uptake of fibronectin-binding pathogens
[作者:Hoffmann, C; Berking, A; Agerer, F; Buntru, A; Neske, F; Chhatwal, GS; Ohlsen, K; Hauck, CR,期刊:Journal of cell science, 页码:4280-4291 , 文章类型: Article,,卷期:2010年123-24]
- Staphylococcus aureus, which is a leading cause of hospital-acquired infections, binds via fibronectin to integrin alpha 5 beta 1, a process that can promote host colonization in vivo. Integrin engagement induces actin c...
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