- Activity of protein kinase CK2 uncouples Bid cleavage from caspase-8 activation
[作者:Hellwig, CT; Ludwig-Galezowska, AH; Concannon, CG; Litchfield, DW; Prehn, JHM; Rehm, M,期刊:Journal of cell science, 页码:1401-1406 , 文章类型: Article,,卷期:2010年123-9]
- In the present study, we quantitatively analysed the interface between apoptosis initiation and execution by determining caspase-8 activation, Bid cleavage and mitochondrial engagement (onset of mitochondrial depolarisat...
- Reconstructing the evolutionary history of the centriole from protein components
[作者:Hodges, ME; Scheumann, N; Wickstead, B; Langdale, JA; Gull, K,期刊:Journal of cell science, 页码:1407-1413 , 文章类型: Article,,卷期:2010年123-9]
- Centrioles are highly conserved structures that fulfil important cellular functions, such as nucleation of cilia and flagella (basal-body function) and organisation of pericentriolar material to form the centrosome. The ...
- Stepwise evolution of the centriole-assembly pathway
[作者:Carvalho-Santos, Z; Machado, P; Branco, P; Tavares-Cadete, F; Rodrigues-Martins, A; Pereira-Leal, JB; Bettencourt-Dias, M,期刊:Journal of cell science, 页码:1414-1426 , 文章类型: Article,,卷期:2010年123-9]
- The centriole and basal body (CBB) structure nucleates cilia and flagella, and is an essential component of the centrosome, underlying eukaryotic microtubule-based motility, cell division and polarity. In recent years, c...
- Dendritic cell podosomes are protrusive and invade the extracellular matrix using metalloproteinase MMP-14
[作者:Gawden-Bone, C; Zhou, ZJ; King, E; Prescott, A; Watts, C; Lucocq, J,期刊:Journal of cell science, 页码:1427-1437 , 文章类型: Article,,卷期:2010年123-9]
- Podosomes are spot-like actin-rich structures formed at the ventral surface of monocytic and haematopoietic cells. Podosomes degrade extracellular matrix and are proposed to be involved in cell migration. A key question ...
- Differential role of Rab proteins in ciliary trafficking: Rab23 regulates Smoothened levels
[作者:Boehlke, C; Bashkurov, M; Buescher, A; Krick, T; John, AK; Nitschke, R; Walz, G; Kuehn, EW,期刊:Journal of cell science, 页码:1460-1467 , 文章类型: Article,,卷期:2010年123-9]
- The structure and function of the primary cilium as a sensory organelle depends on a motor-protein-powered intraflagellar transport system (IFT); defective IFT results in retinal degeneration and pleiotropic disorders su...
- Arabidopsis root K+-efflux conductance activated by hydroxyl radicals: single-channel properties, genetic basis and involvement in stress-induced cell death
[作者:Demidchik, V; Cuin, TA; Svistunenko, D; Smith, SJ; Miller, AJ; Shabala, S; Sokolik, A; Yurin, V,期刊:Journal of cell science, 页码:1468-1479 , 文章类型: Article,,卷期:2010年123-9]
- Reactive oxygen species (ROS) are central to plant stress response, signalling, development and a multitude of other processes. In this study, the plasma-membrane hydroxyl radical (HR)-activated K+ channel responsible fo...
- Rab7b controls trafficking from endosomes to the TGN
[作者:Progida, C; Cogli, L; Piro, F; De Luca, A; Bakke, O; Bucci, C,期刊:Journal of cell science, 页码:1480-1491 , 文章类型: Article,,卷期:2010年123-9]
- Rab7b is a recently identified member of the Rab GTPase protein family and has high similarity to Rab7. It has been reported that Rab7b is lysosome associated, that it is involved in monocytic differentiation and that it...
- Distinct plasma-membrane PtdIns(4)P and PtdIns(4,5)P-2 dynamics in secretagogue-stimulated beta-cells
[作者:Wuttke, A; Sagetorp, J; Tengholm, A,期刊:Journal of cell science, 页码:1492-1502 , 文章类型: Article,,卷期:2010年123-9]
- Phosphoinositides regulate numerous processes in various subcellular compartments. Whereas many stimuli trigger changes in the plasma-membrane PtdIns(4,5)P-2 concentration, little is known about its precursor, PtdIns(4)P...
- Nano-topography sensing by osteoclasts
[作者:Geblinger, D; Addadi, L; Geiger, B,期刊:Journal of cell science, 页码:1503-1510 , 文章类型: Article,,卷期:2010年123-9]
- Bone resorption by osteoclasts depends on the assembly of a specialized, actin-rich adhesive 'sealing zone' that delimits the area designed for degradation. In this study, we show that the level of roughness of the under...
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