- Comparison of DNA Complex Formation Behaviour for Two Closely Related Lexitropsin Analogues
[作者:Parkinson, JA; Khalaf, AI; Anthony, NG; MacKay, SP; Suckling, CJ; Waigh, RD,期刊:Helvetica Chimica Acta, 页码:795-822 , 文章类型: Article,,卷期:2009年92-5]
- Two closely related lexitropsin analogues that differ only in the form of the 'headgroup' functionality (CHO (for 1) vs. Ac (for 2)) have been studied in their DNA-binding capacity for the sequence d(GCATATATGC) using H-...
- Syntheses of 5-Chlorouracils/Thymines with 1-[Phosphono(Methyl/Difluoromethyl)]-1,2-Unsaturated-Moiety-Substituted Methyl Groups at N(1) and Human Thymidine Phosphorylase Inhibitory Activity
[作者:Birck, MR; Clinch, K; Gainsford, GJ; Schramm, VL; Tyler, PC,期刊:Helvetica Chimica Acta, 页码:823-838 , 文章类型: Article,,卷期:2009年92-5]
- By attaching (methyl)- or (difluoromethyl)-phosphonate groups to the 1-positions of ethene, cyclopentene or benzene, and attaching 1-(methyl)-5-chlorouracil or 1-(methyl)thymine groups to the corresponding 2-positions, c...
- Stereoselective Synthesis of cis- and trans-3,4-Dihydro-3,4,8-trihydroxynaphthalen-1(2H)-one
[作者:Couche, E; Fkyerat, A; Tabacchi, R,期刊:Helvetica Chimica Acta, 页码:903-917 , 文章类型: Article,,卷期:2009年92-5]
- A short and efficient protocol for the stereoselective synthesis of racemic trans- and cis-3,4-dihydro3,4,8-trihydroxynaphthalen-1(2H)-one (1 and 2, resp.), is described, comprising nine and eight steps starting from com...
- Synthesis and Evaluation of N-Acetyl-2-amino-2-deoxy-alpha-D-galactosyl 1-Thio-7-oxaceramide, a New Analogue of alpha-D-Galactosyl Ceramide
[作者:Rajan, R; Mathew, T; Buffa, R; Bornancin, F; Cavallari, M; Nussbaumer, P; De Libero, G; Vasella, A,期刊:Helvetica Chimica Acta, 页码:918-927 , 文章类型: Article,,卷期:2009年92-5]
- The N-acetyl-2-amino-2-deoxy-alpha-D-galactopyranosyl 1-thio-7-oxaceramide 1 was synthesized by substituting the 7-oxasphingosine triflate 3 with alpha-D-N-acetyl-1-thiogalactosamine (2). The triflate 3 was obtained from...
- Two New Quinoline Alkaloid Mannopyranosides from Solidago canadensis
[作者:Li, YK; Zhao, QJ; Hu, J; Zou, Z; He, XY; Yuan, HB; Shi, XY,期刊:Helvetica Chimica Acta, 页码:928-931 , 文章类型: Article,,卷期:2009年92-5]
- Two novel quinoline alkaloid beta-D-mannopyranosides, named dictamnine-7-beta-D-mannopyranoside (1) and 8-methoxydictamnine-7-beta-D-mannopyranoside (2), were isolated from the whole plant of Solidago canadensis. Their s...
- Two New C-21 Steroidal Glycosides from the Stems of Cynanchum paniculatum KiTAG.
[作者:Huang, X; Tan, AM; Yang, SB; Zhang, AY; Zhang, H,期刊:Helvetica Chimica Acta, 页码:937-943 , 文章类型: Article,,卷期:2009年92-5]
- Two new glycosides, (3 beta,8 beta,9 alpha,16 alpha,17 alpha)-14,16 beta: 15,20 alpha:18,20 beta-triepoxy-16 alpha, 17 alpha-dihydroxy-14-oxo-13, 14:14, 15-disecopregna-5,13(18)-dien-3-yl alpha-cymaropyranosyl-(1 -> 4)-a...
- One-Pot Three-Component Synthesis of 2-(Alkylimino)-7-oxo-1-oxa-6-azaspiro[4.4]nona-3,8-diene-3,4-dicarboxylates
[作者:Adib, M; Moghimi, S; Sayahi, MH; Bijanzadeh, HR,期刊:Helvetica Chimica Acta, 页码:944-949 , 文章类型: Article,,卷期:2009年92-5]
- The reactive zwitterionic 1:1 intermediate 6 generated in situ from the reaction between an isocyanide 2 and a dialkyl acetylenedicarboxylate (=dialkyl but-2-ynedioate) 3 was trapped by an N-arylmaleimide or -phthalimide...
- Secocycloartane Triterpenoidal Saponins from the Leaves of Astragalus membranaceus BUNGE
[作者:Kuang, HX; Okada, Y; Yang, BY; Tian, ZK; Okuyama, T,期刊:Helvetica Chimica Acta, 页码:950-958 , 文章类型: Article,,卷期:2009年92-5]
- Two new 9,10-secocycloartane triterpenoidal saponins. named huangqiyenins E (1) and F (2) were isolated from the leaves of Astragalus membranaceus BUNGE. Enzymatic hydrolysis of 1 and 2 afforded the aglycones huangqiyege...
- Synthesis of Substituted 1,8-Naphthyridine-3-carboxylates from Baylis-Hillman Adducts of Substituted 2-Chloronicotinaldehydes
[作者:Narender, P; Ravinder, M; Sadhu, PS; Raju, BC; Ramesh, C; Rao, VJ,期刊:Helvetica Chimica Acta, 页码:959-966 , 文章类型: Article,,卷期:2009年92-5]
- A series of substituted 1,8-naphthyridine-3-carboxylates were synthesized for the first time from the Baylis-Hillman adducts obtained from 2-chloronicotinaldehyde derivatives. Three methods were adopted to synthesize 1,8...
- Stereoselective Routes for the Total Synthesis of (+)-Cryptocarya Diacetate
[作者:Sabitha, G; Reddy, NM; Prasad, MN; Yadav, JS,期刊:Helvetica Chimica Acta, 页码:967-976 , 文章类型: Article,,卷期:2009年92-5]
- A stereoselective total synthesis of (+)-cryptocarya diacetate (1) was achieved by two different routes (Schemes 2 and 3). The sequences involve LiAlH4/LiI reduction, ring-closing metathesis, Prins cyclization, Wacker ox...
- Nitrogen-Rich Salts Based on the Energetic 5,5 '-(Hydrazine-1,2-diyl)bis[1H-tetrazolide] Anion
[作者:Eberspacher, M; Klapotke, TM; Sabate, CM,期刊:Helvetica Chimica Acta, 页码:977-996 , 文章类型: Article,,卷期:2009年92-5]
- The reaction of 5,5'-(hydrazine-1,2-diyl)bis[1H-tetrizole] (HBT) with N-bases yielded a new family of energetic N-rich salts based on the 5,5'-(hydrazine-1,2-diyl)bis[1H-tetrazol-1-ide] anion with ammonium (see 1), hydra...
- Two New Secolignans from the Roots of Urtica fissa E. PRITZ
[作者:Ji, BQ; Yan, XG; Duan, LX; Tang, L; Shi, LY; Wang, YQ; Feng, BM,期刊:Helvetica Chimica Acta, 页码:997-1001 , 文章类型: Article,,卷期:2009年92-5]
- Two new secolignans, {(3S,4S)-4-[bis(4-hydroxy-3-methoxyphenyl)methyl]-2-oxotetrthydrofuran-3yl}methyl beta-D-glucopyranoside (1) and its stereoisomer {(3S,4R)-4-[bis(4-hydroxy-3-methoxyphenyl)methyl]-2-oxotetrahydrofura...
|