- Dynamics of the Putative RNA Helicase Spb4 during Ribosome Assembly in Saccharomyces cerevisiae
[作者:Garcia-Gomez, JJ; Lebaron, S; Froment, C; Monsarrat, B; Henry, Y; de la Cruz, J,期刊:Molecular and Cellular Biology, 页码:4156-4164 , 文章类型: Article,,卷期:2011年31-20]
- Spb4 is a putative ATP-dependent RNA helicase that is required for proper processing of 27SB pre-rRNAs and therefore for 60S ribosomal subunit biogenesis. To define the timing of association of this protein with preribos...
- Deregulation of the p57-E2F1-p53 Axis Results in Nonobstructive Hydrocephalus and Cerebellar Malformation in Mice
[作者:Matsumoto, A; Susaki, E; Onoyama, I; Nakayama, K; Hoshino, M; Nakayama, KI,期刊:Molecular and Cellular Biology, 页码:4176-4192 , 文章类型: Article,,卷期:2011年31-20]
- The cyclin-dependent kinase inhibitor (CKI) p57(Kip2) plays a pivotal role in cell cycle arrest during development, in particular, in the regulation of the entry of proliferating progenitors into quiescence. The gene enc...
- Spt6 Is Required for Heterochromatic Silencing in the Fission Yeast Schizosaccharomyces pombe
[作者:Kiely, CM; Marguerat, S; Garcia, JF; Madhani, HD; Bahler, J; Winston, F,期刊:Molecular and Cellular Biology, 页码:4193-4204 , 文章类型: Article,,卷期:2011年31-20]
- Spt6 is a conserved factor, critically required for several transcription- and chromatin-related processes. We now show that Spt6 and its binding partner, Iws1, are required for heterochromatic silencing in Schizosacchar...
- Reducing Plasma Membrane Sphingomyelin Increases Insulin Sensitivity
[作者:Li, ZQ; Zhang, HQ; Liu, J; Liang, CP; Li, Y; Li, Y; Teitelman, G; Beyer, T; Bui, HH; Peake, DA; Zhang, YY; Sanders, PE; Kuo, MS; Park, TS; Cao, GQ; Jiang, XC,期刊:Molecular and Cellular Biology, 页码:4205-4218 , 文章类型: Article,,卷期:2011年31-20]
- It has been shown that inhibition of de novo sphingolipid synthesis increases insulin sensitivity. For further exploration of the mechanism involved, we utilized two models: heterozygous serine palmitoyltransferase (SPT)...
- Competitive Regulation of Nucleolin Expression by HuR and miR-494
[作者:Tominaga, K; Srikantan, S; Lee, EK; Subaran, SS; Martindale, JL; Abdelmohsen, K; Gorospe, M,期刊:Molecular and Cellular Biology, 页码:4219-4231 , 文章类型: Article,,卷期:2011年31-20]
- The RNA-binding protein (RBP) nucleolin promotes the expression of several proliferative proteins. Nucleolin levels are high in cancer cells, but the mechanisms that control nucleolin expression are unknown. Here, we sho...
- QKI-Mediated Alternative Splicing of the Histone Variant MacroH2A1 Regulates Cancer Cell Proliferation
[作者:Novikov, L; Park, JW; Chen, H; Klerman, H; Jalloh, AS; Gamble, MJ,期刊:Molecular and Cellular Biology, 页码:4244-4255 , 文章类型: Article,,卷期:2011年31-20]
- The histone variant macroH2A1 contains a carboxyl-terminal similar to 30-kDa domain called a macro domain. MacroH2A1 is produced as one of two alternatively spliced forms, macroH2A1.1 and macroH2A1.2. While the macro dom...
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