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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共9条记录   Ion Channels as Therapeutic Targets for Neuropathic Pain [作者：Shieh, CC,期刊：Current Pharmaceutical Design, 页码：1709-1710 , 文章类型： Editorial Material，,卷期：2009年15-15] Neuropathic Pain: Models and Mechanisms [作者：Boyce-Rustay, JM; Jarvis, MF,期刊：Current Pharmaceutical Design, 页码：1711-1716 , 文章类型： Review，,卷期：2009年15-15] Advances in the characterization of pain signaling in recent years indicate that distinct neurophysiological and neurochemical mechanisms contribute to pain arising from injury to the nervous system (neuropathic pain). T... Purinergic Receptors and Pain [作者：Burnstock, G,期刊：Current Pharmaceutical Design, 页码：1717-1735 , 文章类型： Review，,卷期：2009年15-15] There is a brief summary of the early background literature about purinergic signalling and its involvement in pain, of ATP storage, release and ectoenzymatic breakdown and of the current classification of receptor subty... TRP Channels and Pain [作者：Cortright, DN; Szallasi, A,期刊：Current Pharmaceutical Design, 页码：1736-1749 , 文章类型： Review，,卷期：2009年15-15] Preclinical research has identified an array of ion channels in sensory neurons involved in the generation and transduction of pain as potential targets for pharmacological intervention. Paramount among these new targets... Acid Sensing Ion Channels and Acid Nociception [作者：Dube, GR; Elagoz, A; Mangat, H,期刊：Current Pharmaceutical Design, 页码：1750-1766 , 文章类型： Review，,卷期：2009年15-15] Acid Sensing Ion Channels (ASICs) are a family of cation channels expressed principally in neurons and that are activated by protons. The sensitivity of ASICs to acidosis and their distribution in primary sensory neurons... Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels and Pain [作者：Dunlop, J; Vasilyev, D; Lu, P; Cummons, T; Bowlby, MR,期刊：Current Pharmaceutical Design, 页码：1767-1772 , 文章类型： Review，,卷期：2009年15-15] Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels underlie the pacemaker currents in neurons and cardiac cells designated as I-h and I-f, respectively. HCN channels are activated at negative membrane pot... Kv7 Channels as Targets for the Treatment of Pain [作者：Wickenden, AD; McNaughton-Smith, G,期刊：Current Pharmaceutical Design, 页码：1773-1798 , 文章类型： Review，,卷期：2009年15-15] Kv7.x channels are a family of six transmembrane domain, single pore-loop, voltage-gated K+ channels. Five members of the family have been identified to date, including the cardiac channel Kv7.1 (formerly known as KvLQT1... Continuous Nanostructures for the Controlled Release of Drugs [作者：Venugopal, J; Prabhakaran, MP; Low, S; Choon, AT; Deepika, G; Dev, VRG; Ramakrishna, S,期刊：Current Pharmaceutical Design, 页码：1799-1808 , 文章类型： Review，,卷期：2009年15-15] The annual world wide market for controlled release of polymer systems which extends beyond drug delivery is now estimated to $60 billion and these systems are used by over 100 million people each year. It was estimated ... Cardiovascular Biology of Interleukin-6 [作者：Abeywardena, MY; Leifert, WR; Warnes, KE; Varghese, JN; Head, RJ,期刊：Current Pharmaceutical Design, 页码：1809-1821 , 文章类型： Review，,卷期：2009年15-15] Interleukin-6 (IL-6) is a multifunctional pro-inflammatory cytokine that is tightly regulated and expressed at low levels in healthy individuals. Increased IL-6 expression has been associated with a variety of diseases, ...