- Identification and Characterization of Alternatively Transcribed Form of Peroxiredoxin IV Gene That Is Specifically Expressed in Spermatids of Postpubertal Mouse Testis
[作者:Yim, SH; Kim, YJ; Oh, SY; Fujii, J; Zhang, Y; Gladyshev, VN; Rhee, SG,期刊:Journal of Biological Chemistry, 页码:39002-39012 , 文章类型: Article,,卷期:2011年286-45]
- 2-Cysteine (Cys) peroxiredoxins (Prxs), which include mammalian Prxs I-IV, possess two conserved Cys residues that are readily oxidized by H(2)O(2) to form a disulfide. In the case of Prx I-III, the disulfide is reduced ...
- Calpastatin Domain L Is a Partial Agonist of the Calmodulin-binding Site for Channel Activation in Cav1.2 Ca(2+) Channels
[作者:Minobe, E; Asmara, H; Saud, ZA; Kameyama, M,期刊:Journal of Biological Chemistry, 页码:39013-39022 , 文章类型: Article,,卷期:2011年286-45]
- Cav1.2 Ca(2+) channel activity diminishes in inside-out patches (run-down). Previously, we have found that with ATP, calpastatin domain L (CSL) and calmodulin (CaM) recover channel activity from the run-down in guinea pi...
- Francisella tularensis Reveals a Disparity between Human and Mouse NLRP3 Inflammasome Activation
[作者:Atianand, MK; Duffy, EB; Shah, A; Kar, S; Malik, M; Harton, JA,期刊:Journal of Biological Chemistry, 页码:39033-39042 , 文章类型: Article,,卷期:2011年286-45]
- Pathogen-triggered activation of the inflammasome complex leading to caspase-1 activation and IL-1 beta production involves similar sensor proteins between mouse and human. However, the specific sensors used may differ b...
- Inactivation of Glycogen Synthase Kinase-3 beta Is Required for Osteoclast Differentiation
[作者:Jang, HD; Shin, JH; Park, DR; Hong, JH; Yoon, K; Ko, R; Ko, CY; Kim, HS; Jeong, D; Kim, N; Lee, SY,期刊:Journal of Biological Chemistry, 页码:39043-39050 , 文章类型: Article,,卷期:2011年286-45]
- Glycogen synthase kinase-3 beta (GSK-3 beta is a serine/threonine kinase originally identified as a regulator of glycogen deposition. Although the role of GSK-3 beta in osteoblasts is well characterized as a negative reg...
- Inner Mitochondrial Translocase Tim50 Interacts with 3 beta-Hydroxysteroid Dehydrogenase Type 2 to Regulate Adrenal and Gonadal Steroidogenesis
[作者:Pawlak, KJ; Prasad, M; Thomas, JL; Whittal, RM; Bose, HS,期刊:Journal of Biological Chemistry, 页码:39130-39140 , 文章类型: Article,,卷期:2011年286-45]
- In the adrenals, testes, and ovaries, 3 beta-hydroxysteroid dehydrogenase type 2 (3 beta HSD2) catalyzes the conversion of pregnenolone to progesterone and dehydroepiandrostenedione to androstenedione. Alterations in thi...
- Intranodal Interaction with Dendritic Cells Dynamically Regulates Surface Expression of the Co-stimulatory Receptor CD226 Protein on Murine T Cells
[作者:Seth, S; Qiu, Q; Danisch, S; Maier, MK; Braun, A; Ravens, I; Czeloth, N; Hyde, R; Dittrich-Breiholz, O; Forster, R; Bernhardt, G,期刊:Journal of Biological Chemistry, 页码:39153-39163 , 文章类型: Article,,卷期:2011年286-45]
- Dendritic cells (DCs) are the most potent antigen-presenting cells of the immune system. Depending on their maturation status, they prime T cells to induce adaptive immunity or tolerance. DCs express CD155, an immunoglob...
- Jumping Mode Atomic Force Microscopy on Grana Membranes from Spinach
[作者:Sznee, K; Dekker, JP; Dame, RT; van Roon, H; Wuite, GJL; Frese, RN,期刊:Journal of Biological Chemistry, 页码:39164-39171 , 文章类型: Article,,卷期:2011年286-45]
- The thylakoid membrane system is a complex membrane system that organizes and reorganizes itself to provide plants optimal chemical energy from sunlight under different and varying environmental conditions. Grana membran...
- MicroRNA miR-21 Regulates the Metastatic Behavior of B16 Melanoma Cells
[作者:Yang, CH; Yue, JM; Pfeffer, SR; Handorf, CR; Pfeffer, LM,期刊:Journal of Biological Chemistry, 页码:39172-39178 , 文章类型: Article,,卷期:2011年286-45]
- MicroRNA-21 (miR-21) is overexpressed in many human tumors and has been linked to various cellular processes altered in cancer. miR-21 is also up-regulated by a number of inflammatory agents, including IFN, which is of p...
- A Novel NADH-dependent and FAD-containing Hydroxylase Is Crucial for Nicotine Degradation by Pseudomonas putida
[作者:Tang, HZ; Yao, YX; Zhang, DK; Meng, XZ; Wang, LJ; Yu, H; Ma, LY; Xu, P,期刊:Journal of Biological Chemistry, 页码:39179-39187 , 文章类型: Article,,卷期:2011年286-45]
- Nicotine, the main alkaloid produced by Nicotiana tabacum and other Solanaceae, is very toxic and may be a leading toxicant causing preventable disease and death, with the rise in global tobacco consumption. Several diff...
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