- Evidence for a Complex of Transcription Factor IIB (TFIIB) with Poly(A) Polymerase and Cleavage Factor 1 Subunits Required for Gene Looping
[作者:Medler, S; Al Husini, N; Raghunayakula, S; Mukundan, B; Aldea, A; Ansari, A,期刊:Journal of Biological Chemistry, 页码:33709-33718 , 文章类型: Article,,卷期:2011年286-39]
- Gene looping, defined as the interaction of the promoter and the terminator regions of a gene during transcription, requires transcription factor IIB (TFIIB). We have earlier demonstrated association of TFIIB with the di...
- Impaired alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) Receptor Trafficking and Function by Mutant Huntingtin
[作者:Mandal, M; Wei, J; Zhong, P; Cheng, J; Duffney, LJ; Liu, WH; Yuen, EY; Twelvetrees, AE; Li, SH; Li, XJ; Kittler, JT; Yan, Z,期刊:Journal of Biological Chemistry, 页码:33719-33728 , 文章类型: Article,,卷期:2011年286-39]
- Emerging evidence from studies of Huntington disease (HD) pathophysiology suggests that huntingtin (htt) and its associated protein HAP1 participate in intracellular trafficking and synaptic function. However, it is larg...
- Caspase-1 Protein Induces Apoptosis-associated Speck-like Protein Containing a Caspase Recruitment Domain (ASC)mediated Necrosis Independently of Its Catalytic Activity
[作者:Motani, K; Kushiyama, H; Imamura, R; Kinoshita, T; Nishiuchi, T; Suda, T,期刊:Journal of Biological Chemistry, 页码:33963-33972 , 文章类型: Article,,卷期:2011年286-39]
- The adaptor protein, apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), connects pathogen/danger sensors such as NLRP3 and NLRC4 with caspases and is involved in inflammation and cell ...
- Green Tea Polyphenols Control Dysregulated Glutamate Dehydrogenase in Transgenic Mice by Hijacking the ADP Activation Site
[作者:Li, CH; Li, M; Chen, P; Narayan, S; Matschinsky, FM; Bennett, MJ; Stanley, CA; Smith, TJ,期刊:Journal of Biological Chemistry, 页码:34164-34174 , 文章类型: Article,,卷期:2011年286-39]
- Glutamate dehydrogenase (GDH) catalyzes the oxidative deamination of L-glutamate and, in animals, is extensively regulated by a number of metabolites. Gain of function mutations in GDH that abrogate GTP inhibition cause ...
- beta-Amyloid Peptide Variants in Brains and Cerebrospinal Fluid from Amyloid Precursor Protein (APP) Transgenic Mice COMPARISON WITH HUMAN ALZHEIMER AMYLOID
[作者:Schieb, H; Kratzin, H; Jahn, O; Mobius, W; Rabe, S; Staufenbiel, M; Wiltfang, J; Klafki, HW,期刊:Journal of Biological Chemistry, 页码:33747-33758 , 文章类型: Article,,卷期:2011年286-39]
- In this study, we report a detailed analysis of the different variants of amyloid-beta (A beta) peptides in the brains and the cerebrospinal fluid from APP23 transgenic mice, expressing amyloid precursor protein with the...
- Gelsolin and Non-muscle Myosin IIA Interact to Mediate Calcium-regulated Collagen Phagocytosis
[作者:Arora, PD; Wang, YQ; Janmey, PA; Bresnick, A; Yin, HL; McCulloch, CA,期刊:Journal of Biological Chemistry, 页码:34184-34198 , 文章类型: Article,,卷期:2011年286-39]
- The formation of adhesion complexes is the rate-limiting step for collagen phagocytosis by fibroblasts, but the role of Ca(2+) and the potential interactions of actin-binding proteins in regulating collagen phagocytosis ...
- The Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase/Ribosomal S6 Protein Kinase 1 Cascade Phosphorylates cAMP Response Element-binding Protein to Induce MUC5B Gene Expression via D-Prostanoid Receptor Signaling
[作者:Choi, YH; Lee, SN; Aoyagi, H; Yamasaki, Y; Yoo, JY; Park, B; Shin, DM; Yoon, HG; Yoon, JH,期刊:Journal of Biological Chemistry, 页码:34199-34214 , 文章类型: Article,,卷期:2011年286-39]
- Mucus hypersecretion is a prominent feature of respiratory diseases, and MUC5B is a major airway mucin. Mucin gene expression can be affected by inflammatory mediators, including prostaglandin (PG) D(2), an inflammatory ...
- Remodeling of Nucleoprotein Complexes Is Independent of the Nucleotide State of a Mutant AAA plus Protein
[作者:Saxena, R; Rozgaja, T; Grimwade, J; Crooke, E,期刊:Journal of Biological Chemistry, 页码:33770-33777 , 文章类型: Article,,卷期:2011年286-39]
- DnaA protein, a member of the AAA+ (ATPase associated with various cellular activities) family, initiates DNA synthesis at the chromosomal origin of replication (oriC) and regulates the transcription of several genes, in...
- Quantitative Mass Spectrometry Reveals Dynamics of Factor-inhibiting Hypoxia-inducible Factor-catalyzed Hydroxylation
[作者:Singleton, RS; Trudgian, DC; Fischer, R; Kessler, BM; Ratcliffe, PJ; Cockman, ME,期刊:Journal of Biological Chemistry, 页码:33784-33794 , 文章类型: Article,,卷期:2011年286-39]
- The asparaginyl hydroxylase, factor-inhibiting hypoxia-inducible factor (HIF), is central to the oxygen-sensing pathway that controls the activity of HIF. Factor-inhibiting HIF (FIH) also catalyzes the hydroxylation of a...
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