- Hypermethylation of CXCR4 promoter in CD34(+) cells from patients with primary myelofibrosis
[作者:Bogani, C; Ponziani, V; Guglielmelli, P; Desterke, C; Rosti, V; Bosi, A; Le Bousse-Kerdiles, MC; Barosi, G; Vannucchi, AM,期刊:Stem Cells, 页码:1920-1930 , 文章类型: Article,,卷期:2008年26-8]
- Constitutive mobilization of CD34(+) cells in patients with primary myelofibrosis (PMF) has been attributed to proteolytic disruption of the CXCR4/SDF-1 axis and reduced CXCR4 expression. We document here that the number...
- Regulation of self-renewal and pluripotency by Sox2 in human embryonic stem cells
[作者:Fong, HL; Hohenstein, KA; Donovan, PJ,期刊:Stem Cells, 页码:1931-1938 , 文章类型: Article,,卷期:2008年26-8]
- Human embryonic stem (hES) cells, derived from blastocysts, are capable of unlimited self-renewal and differentiation into all cell lineages of the body. Because of their pluripotent nature, hES cells are valuable tools ...
- Canonical Wnt signaling controls proliferation of retinal stem/progenitor cells in postembryonic Xenopus eyes
[作者:Denayer, T; Locker, M; Borday, C; Deroo, T; Janssens, S; Hecht, A; van Roy, F; Perron, M; Vleminckx, K,期刊:Stem Cells, 页码:2063-2074 , 文章类型: Article,,卷期:2008年26-8]
- Vertebrate retinal stem cells, which reside quiescently within the ciliary margin, may offer a possibility for treatment of degenerative retinopathies. The highly proliferative retinal precursor cells in Xenopus eyes are...
- Human bone marrow mesenchymal stem cells accelerate recovery of acute renal injury and prolong survival in mice
[作者:Morigi, M; Introna, M; Imberti, B; Corna, D; Abbate, M; Rota, C; Rottoli, D; Benigni, A; Perico, N; Zoja, C; Rambaldi, A; Remuzzi, A; Remuzzi, G,期刊:Stem Cells, 页码:2075-2082 , 文章类型: Article,,卷期:2008年26-8]
- Transplantation of bone marrow mesenchymal stem cells (BM-MSC) or stromal cells from rodents has been identified as a strategy for renal repair in experimental models of acute kidney injury (AKI), a highly life-threateni...
- Evidence that very small embryonic-like stem cells are mobilized into peripheral blood
[作者:Kucia, MJ; Wysoczynski, M; Wu, W; Zuba-Surma, EK; Ratajczak, J; Ratajczak, MZ,期刊:Stem Cells, 页码:2083-2092 , 文章类型: Article,,卷期:2008年26-8]
- Recently, we identified in murine adult tissues, including bone marrow, a population of very small embryonic-like (VSEL) stem cells. Here, we provide further evidence that tinder steady-state conditions these cells circu...
- Criticality of the biological and physical stimuli array inducing resident cardiac stem cell determination
[作者:Forte, G; Carotenuro, F; Pagliari, F; Pagliari, S; Cossa, P; Fiaccavento, R; Ahiuwalia, A; Vozzi, G; Vinci, B; Serafino, A; Rinaldi, A; Tizaversa, E; Carosella, L; Minieri, M; Di Nardo, P,期刊:Stem Cells, 页码:2093-2103 , 文章类型: Article,,卷期:2008年26-8]
- The replacement of injured cardiac contractile cells with stem cell-derived functionally efficient cardiomyocytes has been envisaged as the resolutive treatment for degenerative heart diseases. Nevertheless, many technic...
- Fate-mapping evidence that hepatic stellate cells are epithelial progenitors in adult mouse livers
[作者:Yang, L; Jung, YM; Omenetti, A; Witek, RP; Choi, S; Vandongen, HM; Huang, JW; Alpini, GD; Diehl, AM,期刊:Stem Cells, 页码:2104-2113 , 文章类型: Article,,卷期:2008年26-8]
- Liver injury activates quiescent hepatic stellate cells (Q-HSC) to proliferative myofibroblasts. Accumulation of myofibroblastic hepatic stellate cells (MF-HSC) sometimes causes cirrhosis and liver failure. However, MF-H...
- Osteopontin promotes the development of natural killer cells from hematopoietic stem cells
[作者:Chung, JW; Kim, MS; Piao, ZH; Jeong, M; Yoon, SR; Shin, N; Kim, SY; Hwang, ES; Yang, Y; Lee, YH; Kim, YS; Choi, I,期刊:Stem Cells, 页码:2114-2123 , 文章类型: Article,,卷期:2008年26-8]
- The detailed mechanisms driving the development of natural killer (NK) cells from hematopoietic stem cells remain to be clearly elucidated. Here, we show that osteopontin (OPN) is a key factor for NK development. OPN-def...
- G9a and Jhdm2a regulate embryonic stem cell fusion-induced reprogramming of adult neural stem cells
[作者:Ma, DK; Chiang, CHJ; Ponnusamy, K; Ming, GL; Song, HJ,期刊:Stem Cells, 页码:2131-2141 , 文章类型: Article,,卷期:2008年26-8]
- Somatic nuclei can be reprogrammed to pluripotency through fusion with embryonic stem cells (ESCs). The underlying mechanism is largely unknown, primarily because of a lack of effective approaches to monitor and quantita...
- Lentiviral vector gene transfer is limited by the proteasome at postentry steps in various types of stem cells
[作者:de Sio, FRS; Gritti, A; Cascio, P; Neri, M; Sampaolesi, M; Galli, C; Luban, J; Naldini, L,期刊:Stem Cells, 页码:2142-2152 , 文章类型: Article,,卷期:2008年26-8]
- The isolation of human embryonic and somatic stem cells of different types has made it possible to design novel gene and cell replacement therapies. Vectors derived from retro/lentiviruses are used to stably introduce ge...
- Embryonic stem cell-derived neurons as a cellular system to study gene function: Lack of amyloid precursor proteins APP and APLP2 leads to defective synaptic transmission
[作者:Schrenk-Siemens, K; Perez-Alcala, S; Richter, J; Lacroix, E; Rahuel, J; Korte, M; Muller, U; Barde, YA; Bibel, M,期刊:Stem Cells, 页码:2153-2163 , 文章类型: Article,,卷期:2008年26-8]
- The in vitro generation of uniform populations of neurons from mouse embryonic stem cells (ESCs) provides a novel opportunity to study gene function in neurons. This is of particular interest when mutations lead to letha...
- Olfactory mucosa is a potential source for autologous stem cell therapy for Parkinson's disease
[作者:Murrell, W; Wetzig, A; Donnellan, M; Feron, F; Burne, T; Meedeniya, A; Kesby, J; Bianco, J; Perry, C; Silburn, P; Mackay-Sim, A,期刊:Stem Cells, 页码:2183-2192 , 文章类型: Article,,卷期:2008年26-8]
- Parkinson's disease is a complex disorder characterized by degeneration of dopaminergic neurons in the substantia nigra in the brain. Stem cell transplantation is aimed at replacing dopaminergic neurons because the most ...
- Oncostatin M-mediated regulation of KIT-ligand-induced extracellular signal-regulated kinase signaling maintains hematopoietic repopulating activity of Lin(-) CD34(+) CD133(+) cord blood cells
[作者:Oostendorp, RAJ; Gilfillan, S; Parmar, A; Schiemann, M; Marz, S; Niemeyer, M; Schill, S; Hammerschmid, E; Jacobs, VR; Peschel, C; Gotze, KS,期刊:Stem Cells, 页码:2164-2172 , 文章类型: Article,,卷期:2008年26-8]
- We investigated whether KIT signaling was sufficient to maintain human hematopoietic stem cells in culture or whether, as with murine stem cells, signaling through glycoprotein 130 (gp130) is additionally required. Sorte...
- Direct-current electrical field guides neuronal stem/progenitor cell migration
[作者:Li, L; El-Hayek, YH; Liu, BS; Chen, YH; Gomez, E; Wu, XH; Ning, K; Li, LJ; Chang, N; Zhang, L; Wang, ZG; Hu, X; Wan, Q,期刊:Stem Cells, 页码:2193-2200 , 文章类型: Article,,卷期:2008年26-8]
- Direct-current electrical fields (EFs) promote nerve growth and axon regeneration. We report here that at physiological strengths, EFs guide the migration of neuronal stem/progenitor cells (NSPCs) toward the cathode. F,F...
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