- Colorectal Cancer Stem Cells
[作者：Vaiopoulos, AG; Kostakis, ID; Koutsilieris, M; Papavassiliou, AG,期刊：Stem Cells, 页码：363-371 , 文章类型： Review，,卷期：2012年30-3]
- Colorectal cancer (CRC) is one of the most commonly diagnosed and lethal cancers worldwide. It is a multistep process that requires the accumulation of genetic/epigenetic aberrations. There are several issues concerning ...
- Role of BMI1, a Stem Cell Factor, in Cancer Recurrence and Chemoresistance: Preclinical and Clinical Evidences
[作者：Siddique, HR; Saleem, M,期刊：Stem Cells, 页码：372-378 , 文章类型： Review，,卷期：2012年30-3]
- There is increasing evidence that a variety of cancers arise from transformation of normal stem cells to cancer stem cells (CSCs). CSCs are thought to sustain cancer progression, invasion, metastasis, and recurrence afte...
- Applying Stem Cell Biology to Vascular Structures
[作者：Bostrom, KI; Garfinkel, A; Yao, YC; Jumabay, M,期刊：Stem Cells, 页码：386-391 , 文章类型： Review，,卷期：2012年30-3]
- The vasculature, an organ that penetrates every other organ, is ideally poised to be the site where pools of stem cells are placed, to be deployed and committed in response to feedback regulation, and to respond to deman...
- In Vivo Generation of Neural Tumors from Neoplastic Pluripotent Stem Cells Models Early Human Pediatric Brain Tumor Formation
[作者：Werbowetski-Ogilvie, TE; Morrison, LC; Fiebig-Comyn, A; Bhatia, M,期刊：Stem Cells, 页码：392-404 , 文章类型： Article，,卷期：2012年30-3]
- Recent studies have identified gene signatures in malignant tumors that are associated with human embryonic stem cells, suggesting a molecular relationship between aggressive cancers and pluripotency. Here, we characteri...
- REST Regulates Oncogenic Properties of Glioblastoma Stem Cells
[作者：Kamal, MM; Sathyan, P; Singh, SK; Zinn, PO; Marisetty, AL; Liang, SD; Gumin, J; El-Mesallamy, HO; Suki, D; Colman, H; Fuller, GN; Lang, FF; Majumder, S,期刊：Stem Cells, 页码：405-414 , 文章类型： Article，,卷期：2012年30-3]
- Glioblastoma multiforme (GBM) tumors are the most common malignant primary brain tumors in adults. Although many GBM tumors are believed to be caused by self-renewing, glioblastoma-derived stem-like cells (GSCs), the mec...
- Intratumoral Heterogeneity in the Self-Renewal and Tumorigenic Differentiation of Ovarian Cancer
[作者：Abelson, S; Shamai, Y; Berger, L; Shouval, R; Skorecki, K; Tzukerman, M,期刊：Stem Cells, 页码：415-424 , 文章类型： Article，,卷期：2012年30-3]
- Resistance to anticancer therapy has been attributed to interindividual differences in gene expression pathways among tumors, and to the existence within tumors of cancer stem cells with self-renewal capacity. In previou...
- Repressor Element 1 Silencing Transcription Factor Couples Loss of Pluripotency with Neural Induction and Neural Differentiation
[作者：Soldati, C; Bithell, A; Johnston, C; Wong, KY; Teng, SW; Beglopoulos, V; Stanton, LW; Buckley, NJ,期刊：Stem Cells, 页码：425-434 , 文章类型： Article，,卷期：2012年30-3]
- Neural differentiation of embryonic stem cells (ESCs) requires coordinated repression of the pluripotency regulatory program and reciprocal activation of the neurogenic regulatory program. Upon neural induction, ESCs rap...
- Elevated Coding Mutation Rate During the Reprogramming of Human Somatic Cells into Induced Pluripotent Stem Cells
[作者：Ji, JF; Ng, SH; Sharma, V; Neculai, D; Hussein, S; Sam, M; Trinh, Q; Church, GM; Mcpherson, JD; Nagy, A; Batada, NN,期刊：Stem Cells, 页码：435-440 , 文章类型： Article，,卷期：2012年30-3]
- Mutations in human induced pluripotent stem cells (iPSCs) pose a risk for their clinical use due to preferential reprogramming of mutated founder cell and selection of mutations during maintenance of iPSCs in cell cultur...
- Divergent RNA-Binding Proteins, DAZL and VASA, Induce Meiotic Progression in Human Germ Cells Derived In Vitro
[作者：Medrano, JV; Ramathal, C; Nguyen, HN; Simon, C; Pera, RAR,期刊：Stem Cells, 页码：441-451 , 文章类型： Article，,卷期：2012年30-3]
- Our understanding of human germ cell development is limited in large part due to inaccessibility of early human development to molecular genetic analysis. Pluripotent human embryonic stem cells (hESCs) and induced plurip...
- RNA-Binding Protein L1TD1 Interacts with LIN28 via RNA and is Required for Human Embryonic Stem Cell Self-Renewal and Cancer Cell Proliferation
[作者：Narva, E; Rahkonen, N; Emani, MR; Lund, R; Pursiheimo, JP; Nasti, J; Autio, R; Rasool, O; Denessiouk, K; Lahdesmaki, H; Rao, A; Lahesmaa, R,期刊：Stem Cells, 页码：452-460 , 文章类型： Article，,卷期：2012年30-3]
- Human embryonic stem cells (hESC) have a unique capacity to self-renew and differentiate into all the cell types found in human body. Although the transcriptional regulators of pluripotency are well studied, the role of ...
- Protein Kinase C Mediated Extraembryonic Endoderm Differentiation of Human Embryonic Stem Cells
[作者：Feng, XZ; Zhang, JC; Smuga-Otto, K; Tian, SL; Yu, JY; Stewart, R; Thomson, JA,期刊：Stem Cells, 页码：461-470 , 文章类型： Article，,卷期：2012年30-3]
- Unlike mouse embryonic stem cells (ESCs), which are closely related to the inner cell mass, human ESCs appear to be more closely related to the later primitive ectoderm. For example, human ESCs and primitive ectoderm sha...
- Pharmacological Modulation of Human Mesenchymal Stem Cell Chondrogenesis by a Chemically Oversulfated Polysaccharide of Marine Origin: Potential Application to Cartilage Regenerative Medicine
[作者：Merceron, C; Portron, S; Vignes-Colombeix, C; Rederstorff, E; Masson, M; Lesoeur, J; Sourice, S; Sinquin, C; Colliec-Jouault, S; Weiss, P; Vinatier, C; Guicheux, J,期刊：Stem Cells, 页码：471-480 , 文章类型： Article，,卷期：2012年30-3]
- Mesenchymal stem cells (MSCs) are considered as an attractive source of cells for cartilage engineering due to their availability and capacity for expansion and multipotency. Differentiation of MSC into chondrocytes is c...
- Nuclear Fusion-Independent Smooth Muscle Differentiation of Human Adipose-Derived Stem Cells Induced by a Smooth Muscle Environment
[作者：Zhang, R; Jack, GS; Rao, N; Zuk, P; Ignarro, LJ; Wu, B; Rodriguez, LV,期刊：Stem Cells, 页码：481-490 , 文章类型： Article，,卷期：2012年30-3]
- Human adipose-derived stem cells hASC have been isolated and were shown to have multilineage differentiation capacity. Although both plasticity and cell fusion have been suggested as mechanisms for cell differentiation i...
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