- Rai is a New Regulator of Neural Progenitor Migration and Glioblastoma Invasion
[作者：Ortensi, B; Osti, D; Pellegatta, S; Pisati, F; Brescia, P; Fornasari, L; Levi, D; Gaetani, P; Colombo, P; Ferri, A; Nicolis, S; Finocchiaro, G; Pelicci, G,期刊：Stem Cells, 页码：817-832 , 文章类型： Article，,卷期：2012年30-5]
- The invasive nature of glioblastoma (GBM) is one important reason for treatment failure. GBM stem/progenitor cells retain the migratory ability of normal neural stem/progenitor cells and infiltrate the brain parenchyma. ...
- Radiation-Induced Reprogramming of Breast Cancer Cells
[作者：Lagadec, C; Vlashi, E; Della Donna, L; Dekmezian, C; Pajonk, F,期刊：Stem Cells, 页码：833-844 , 文章类型： Article，,卷期：2012年30-5]
- Breast cancers are thought to be organized hierarchically with a small number of breast cancer stem cells (BCSCs) able to regrow a tumor while their progeny lack this ability. Recently, several groups reported enrichment...
- Differential Proteomic Analysis of Human Glioblastoma and Neural Stem Cells Reveals HDGF as a Novel Angiogenic Secreted Factor
[作者：Thirant, C; Galan-Moya, EM; Dubois, LG; Pinte, S; Chafey, P; Broussard, C; Varlet, P; Devaux, B; Soncin, F; Gavard, J; Junier, MP; Chneiweiss, H,期刊：Stem Cells, 页码：845-853 , 文章类型： Article，,卷期：2012年30-5]
- Presence in glioblastomas of cancer cells with normal neural stem cell (NSC) properties, tumor initiating capacity, and resistance to current therapies suggests that glioblastoma stem-like cells (GSCs) play central roles...
- P-Cadherin Is Coexpressed with CD44 and CD49f and Mediates Stem Cell Properties in Basal-like Breast Cancer
[作者：Vieira, AF; Ricardo, S; Ablett, MP; Dionisio, MR; Mendes, N; Albergaria, A; Farnie, G; Gerhard, R; Cameselle-Teijeiro, JF; Seruca, R; Schmitt, F; Clarke, RB; Paredes, J,期刊：Stem Cells, 页码：854-864 , 文章类型： Article，,卷期：2012年30-5]
- Although the luminal progenitor cell of the normal mammary gland hierarchy has been proposed as the cell-of-origin for basal-like breast cancers, finding the cancer stem cell (CSC) phenotype for this malignancy has prove...
- SFRP1 and SFRP2 Dose-Dependently Regulate Midbrain Dopamine Neuron Development In Vivo and in Embryonic Stem Cells
[作者：Kele, J; Andersson, ER; Villaescusa, JC; Cajanek, L; Parish, CL; Bonilla, S; Toledo, EM; Bryja, V; Rubin, JS; Shimono, A; Arenas, E,期刊：Stem Cells, 页码：865-875 , 文章类型： Article，,卷期：2012年30-5]
- Secreted Frizzled related proteins (sFRPs) are a family of proteins that modulate Wnt signaling, which in turn regulates multiple aspects of ventral midbrain (VM) and dopamine (DA) neuron development. However, it is not ...
- CD49f Enhances Multipotency and Maintains Stemness Through the Direct Regulation of OCT4 and SOX2
[作者：Yu, KR; Yang, SR; Jung, JW; Kim, H; Ko, K; Han, DW; Park, SB; Choi, SW; Kang, SK; Scholer, H; Kang, KS,期刊：Stem Cells, 页码：876-887 , 文章类型： Article，,卷期：2012年30-5]
- CD49f (integrin subunit a6) regulates signaling pathways in a variety of cellular activities. However, the role of CD49f in regulating the differentiation and pluripotency of stem cells has not been fully investigated. T...
- Context-Dependent Enhancement of Induced Pluripotent Stem Cell Reprogramming by Silencing Puma
[作者：Lake, BB; Fink, J; Klemetsaune, L; Fu, XM; Jeffers, JR; Zambetti, GP; Xu, Y,期刊：Stem Cells, 页码：888-897 , 文章类型： Article，,卷期：2012年30-5]
- Reprogramming of the somatic state to pluripotency can be induced by a defined set of transcription factors including Oct3/4, Sox2, Klf4, and c-Myc [Cell 2006;126:663-676]. These induced pluripotent stem cells (iPSCs) ho...
- Pluripotent Stem Cell Model Reveals Essential Roles for miR-450b-5p and miR-184 in Embryonic Corneal Lineage Specification
[作者：Shalom-Feuerstein, R; Serror, L; Divonne, SD; Petit, I; Aberdam, E; Camargo, L; Damour, O; Vigouroux, C; Solomon, A; Gaggioli, C; Itskovitz-Eldor, J; Ahmad, S; Aberdam, D,期刊：Stem Cells, 页码：898-909 , 文章类型： Article，,卷期：2012年30-5]
- Approximately 6 million people worldwide are suffering from severe visual impairments or blindness due to corneal diseases. Corneal allogeneic transplantation is often required to restore vision; however, shortage in cor...
- Cnot1, Cnot2, and Cnot3 Maintain Mouse and Human ESC Identity and Inhibit Extraembryonic Differentiation
[作者：Zheng, XF; Dumitru, R; Lackford, BL; Freudenberg, JM; Singh, AP; Archer, TK; Jothi, R; Hu, G,期刊：Stem Cells, 页码：910-922 , 文章类型： Article，,卷期：2012年30-5]
- Embryonic stem cell (ESC) identity and self-renewal is maintained by extrinsic signaling pathways and intrinsic gene regulatory networks. Here, we show that three members of the Ccr4-Not complex, Cnot1, Cnot2, and Cnot3,...
- NADPH Oxidase 2 Regulates Bone Marrow Microenvironment Following Hindlimb Ischemia: Role in Reparative Mobilization of Progenitor Cells
[作者：Urao, N; McKinney, RD; Fukai, T; Ushio-Fukai, M,期刊：Stem Cells, 页码：923-934 , 文章类型： Article，,卷期：2012年30-5]
- Bone marrow (BM) microenvironment, which is regulated by hypoxia and proteolytic enzymes, is crucial for stem/progenitor cell function and mobilization involved in postnatal neovascularization. We demonstrated that NADPH...
- Prolonged Maturation Culture Favors a Reduction in the Tumorigenicity and the Dopaminergic Function of Human ESC-Derived Neural Cells in a Primate Model of Parkinson's Disease
[作者：Doi, D; Morizane, A; Kikuchi, T; Onoe, H; Hayashi, T; Kawasaki, T; Motono, M; Sasai, Y; Saiki, H; Gomi, M; Yoshikawa, T; Hayashi, H; Shinoyama, M; Refaat, MM; Suemori, H; Miyamoto, S; Takahashi, J,期刊：Stem Cells, 页码：935-945 , 文章类型： Article，,卷期：2012年30-5]
- For the safe clinical application of embryonic stem cells (ESCs) for neurological diseases, it is critical to evaluate the tumorigenicity and function of human ESC (hESC)-derived neural cells in primates. We have herein,...
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