- Caspofungin modulates inflammatory responses to Aspergillus fumigatus through stage-specific effects on fungal beta-glucan exposure
[作者:Hohl, TM; Feldmesser, M; Perlin, DS; Pamer, EG,期刊:Journal of Infectious Diseases, 页码:176-185 , 文章类型: Article,,卷期:2008年198-2]
- Echinocandins target fungal beta-1,3 glucan synthesis and are used clinically to treat invasive aspergillosis. Although echinocandins do not completely inhibit in vitro growth of Aspergillus fumigatus, they do induce mor...
- Caspofungin-mediated beta-glucan unmasking and enhancement of human polymorphonuclear neutrophil activity against Aspergillus and non-Aspergillus hyphae
[作者:Lamaris, GA; Lewis, RE; Chamilos, G; May, GS; Safdar, A; Walsh, TJ; Raad, II; Kontoyiannis, DP,期刊:Journal of Infectious Diseases, 页码:186-192 , 文章类型: Article,,卷期:2008年198-2]
- Background. We investigated whether caspofungin and other echinocandins have immune-enhancing properties that influence human polymorphonuclear neutrophil (PMN)-mediated mold hyphal damage.Materials and methods. Using an...
- Transcriptome profile of the vascular endothelial cell response to Candida albicans
[作者:Barker, KS; Park, H; Phan, QT; Xu, LJ; Homayouni, R; Rogers, PD; Filler, SG,期刊:Journal of Infectious Diseases, 页码:193-202 , 文章类型: Article,,卷期:2008年198-2]
- Background. During hematogenously disseminated candidiasis, bloodborne Candida albicans interacts with vascular endothelial cells (ECs), which have the capacity to influence the local inflammatory response to this organi...
- Hepatitis C virus (HCV)-specific immune responses of long-term injection drug users frequently exposed to HCV
[作者:Mizukoshi, E; Eisenbach, C; Edlin, BR; Newton, KP; Raghuraman, S; Weiler-Normann, C; Tobler, LH; Busch, MP; Carrington, M; McKeating, JA; O'Brien, TR; Rehermann, B,期刊:Journal of Infectious Diseases, 页码:203-212 , 文章类型: Article,,卷期:2008年198-2]
- Background. Injection drug users (IDUs) who successfully clear hepatitis C virus (HCV) have a reduced risk of developing chronic reinfection, despite their continuing exposure to the virus. To identify immunological corr...
- Hepatitis C virus-induced secretion of inflammatory chemokines preferentially recruits NKG2A(+) CD8(+) T cells
[作者:Nattermann, J; Sherzada, R; Iwan, A; Bogen, D; Niederle, IM; Schulte, D; Mertens, E; Nischalke, HD; Kramer, B; Sauerbruch, T; Leifeld, L; Spengler, U,期刊:Journal of Infectious Diseases, 页码:213-217 , 文章类型: Article,,卷期:2008年198-2]
- In patients with hepatitis C, a loss-of-function mutation of chemokine receptor CCR5 (CCR5 Delta 32) has been shown to be associated with spontaneous viral clearance and lower levels of hepatic inflammation. In the prese...
- Expression of defective hepatitis B virus particles derived from singly spliced RNA is related to liver disease
[作者:Soussan, P; Pol, J; Garreau, F; Schneider, V; Le Pendeven, C; Nalpas, B; Lacombe, K; Bonnard, P; Pol, S; Kremsdorf, D,期刊:Journal of Infectious Diseases, 页码:218-225 , 文章类型: Article,,卷期:2008年198-2]
- Background. Defective hepatitis B virus (HBV) particles, generated from singly spliced HBV RNA, have been detected in chronic carriers of HBV. The present study was designed to quantify the expression of defective HBV (d...
- Decreased susceptibility to Plasmodium falciparum infection in pregnant women with iron deficiency
[作者:Kabyemela, ER; Fried, M; Kurtis, JD; Mutabingwa, TK; Duffy, PE,期刊:Journal of Infectious Diseases, 页码:163-166 , 文章类型: Article,,卷期:2008年198-2]
- Iron plus folate supplementation increases mortality and morbidity among children in areas of malaria endemicity in Africa, but the effects of supplementation on pregnant women in malaria-endemic areas remain unclear. In...
- Age-related and infection intensity-related shifts in antibody recognition of defined protein antigens in a schistosome-exposed population
[作者:Mutapi, F; Burchmore, R; Mduluza, T; Midzi, N; Turner, CMR; Maizels, RM,期刊:Journal of Infectious Diseases, 页码:167-175 , 文章类型: Article,,卷期:2008年198-2]
- Background. This study compared patterns of recognition of defined Schistosoma haematobium adult worm antigens by serum antibodies from schistosome-exposed Zimbabweans aged 5-18 years.Methods. The population was stratifi...
- Anti-ganglioside antibody induction by swine (A/NJ/1976/H1N1) and other influenza vaccines: Insights into vaccine-associated Guillain-Barre syndrome
[作者:Nachamkin, I; Shadomy, SV; Moran, AP; Cox, N; Fitzgerald, C; Ung, H; Corcoran, AT; Iskander, JK; Schonberger, LB; Chen, RT,期刊:Journal of Infectious Diseases, 页码:226-233 , 文章类型: Article,,卷期:2008年198-2]
- Background. Receipt of an A/NJ/1976/H1N1 "swine flu" vaccine in 1976, unlike receipt of influenza vaccines used in subsequent years, was strongly associated with the development of the neurologic disorder Guillain-Barre ...
- A 96-week comparison of lopinavir-ritonavir combination therapy followed by lopinavir-ritonavir monotherapy versus efavirenz combination therapy
[作者:Cameron, DW; da Silva, BA; Arribas, JR; Myers, RA; Bellos, NC; Gilmore, N; King, MS; Bernstein, BM; Brun, SC; Hanna, GJ,期刊:Journal of Infectious Diseases, 页码:234-240 , 文章类型: Article,,卷期:2008年198-2]
- Antiretroviral-naive HIV-1-infected volunteers received zidovudine/lamivudine plus either lopinavir/ritonavir (n = 104) or efavirenz (n = 51). Lopinavir/ritonavir-treated subjects demonstrating 3 consecutive monthly HIV-...
- Roles of clinical and subclinical reactivated herpes simplex virus type 2 infection and human immunodeficiency virus type 1 (HIV-1)-induced immunosuppression on genital and plasma HIV-1 levels
[作者:Nagot, N; Ouedraogo, A; Konate, I; Weiss, HA; Foulongne, V; Defer, MC; Sanon, A; Becquart, P; Segondy, M; Sawadogo, A; Van de Perre, P; Mayaud, P,期刊:Journal of Infectious Diseases, 页码:241-249 , 文章类型: Article,,卷期:2008年198-2]
- Background. Few longitudinal studies have described the interactions between reactivation of herpes simplex virus type 2 (HSV-2) infection (hereafter, "HSV-2 reactivation") and genital and systemic replication of human i...
- Fibronectin facilitates the invasion of Orientia tsutsugamushi into host cells through interaction with a 56-kDa type-specific antigen
[作者:Lee, JH; Cho, NH; Kim, SY; Bang, SY; Chu, H; Choi, MS; Kim, IS,期刊:Journal of Infectious Diseases, 页码:250-257 , 文章类型: Article,,卷期:2008年198-2]
- Background. Orientia tsutsugamushi, the causative agent of scrub typhus, is an obligate intracellular bacterium. The pathogen's mechanism of cellular invasion is poorly characterized.Methods. Through ligand immunoblots, ...
- Development of real-time in vivo imaging of device-related Staphylococcus epidermidis infection in mice and influence of animal immune status on susceptibility to infection
[作者:Vuong, C; Kocianova, S; Yu, J; Kadurugamuwa, JL; Otto, M,期刊:Journal of Infectious Diseases, 页码:258-261 , 文章类型: Article,,卷期:2008年198-2]
- Staphylococcus epidermidis is the leading cause of hospital-acquired device-related infections, but there is a lack of suitable methods to investigate the pathogenesis of S. epidermidis infection. We created a biolumines...
- Survival advantage of coagulation factor XI-deficient mice during peritoneal sepsis
[作者:Tucker, EI; Gailani, D; Hurst, S; Cheng, QF; Hanson, SR; Gruber, A,期刊:Journal of Infectious Diseases, 页码:271-274 , 文章类型: Article,,卷期:2008年198-2]
- Anticoagulation is a rational approach to the treatment of sepsis-associated consumptive coagulopathy, but its application is limited because of the risk of excessive bleeding. Factor XI (FXI) contributes substantially t...
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