- Do microRNAs regulate bone marrow stem cell niche physiology?
[作者:Laine, SK; Hentunen, T; Laitala-Leinonen, T,期刊:Gene, 页码:1-9 , 文章类型: Review,,卷期:2012年497-1]
- The adult bone marrow, situated within the bone cavity, comprises three distinct stem cell populations: hematopoietic stem cells (HSCs), mesenchymal stromal/stem cells (MSCs) and endothelial progenitor/stem cells (EPCs)....
- KlRox1p contributes to yeast resistance to metals and is necessary for KlYCF1 expression in the presence of cadmium
[作者:Torres, AMR; Maceiras, ML; Belmonte, ER; Naveira, LN; Calvo, MB; Cerdan, ME,期刊:Gene, 页码:27-37 , 文章类型: Article,,卷期:2012年497-1]
- We have characterized the KIROX1 gene from Kluyveromyces lactis and verified that it does not regulate the hypoxic response in this yeast, oppositely to the Saccharomyces cerevisioe homologue ScROX1. The KIROX1 promoter ...
- Calculating phenotypic similarity between genes using hierarchical structure data based on semantic similarity
[作者:Zhang, SZ; Chang, ZQ; Li, ZQ; DuanMu, HZ; Li, ZH; Li, KN; Liu, YF; Qiu, FJ; Xu, Y,期刊:Gene, 页码:58-65 , 文章类型: Article,,卷期:2012年497-1]
- Phenotypic similarity is correlated with a number of measures of gene function, such as relatedness at the level of direct protein-protein interaction. The phenotypic effect of a deleted or mutated gene, which is one par...
- A 40-bp insertion/deletion polymorphism in the constitutive promoter of MDM2 confers risk for hepatocellular carcinoma in a Chinese population
[作者:Dong, D; Gao, XR; Zhu, ZS; Yu, Q; Bian, SZ; Gao, YZ,期刊:Gene, 页码:66-70 , 文章类型: Article,,卷期:2012年497-1]
- The pathogenesis of HCC is a multistage process with the involvement of genetic factors. The aim of the present study is to investigate the possible association between a 40-bp insertion/deletion polymorphism (indel) at ...
- Analysis of the role of p38 MAP kinase in epidermal growth factor-induced JB6 Cl41 cell transformation by cDNA array
[作者:He, ZW; Cui, P; Ye, CG; Ma, WY; Bode, A; Dong, ZG,期刊:Gene, 页码:71-78 , 文章类型: Article,,卷期:2012年497-1]
- To further explore the mechanism of p38 MAP kinase in regulation of JB6 C cell transformation. cDNA array was employed to scan the differential expression genes between DN-p38 cells and CMV-neo JB6 Cl41 cells after EGF s...
- DAG1, no gene for RNA regulation?
[作者:Brancaccio, A,期刊:Gene, 页码:79-82 , 文章类型: Article,,卷期:2012年497-1]
- DAG1 encodes for a precursor protein that liberates the two subunits featured by the dystroglycan (DG) adhesion complex that are involved in an increasing number of cellular functions in a wide variety of cells and tissu...
- A large deletion causes apparent homozygosity for the D1152H mutation in the cystic fibrosis transmembrane regulator (CFTR) gene
[作者:Diana, A; Tesse, R; Polizzi, AM; Santostasi, T; Manca, A; Leonetti, G; Seia, M; Porcaro, L; Cavallo, L,期刊:Gene, 页码:90-92 , 文章类型: Article,,卷期:2012年497-1]
- We report the case of a patient with an apparent homozygosity for the D1152H mutation located in exon 18 of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The parents had no personal history of cyst...
- Association between C3orf21, TP63 polymorphisms and environment and NSCLC in never-smoking Chinese population
[作者:Zhang, YJ; Gu, CP; Shi, H; Zhang, AQ; Kong, XM; Bao, WL; Deng, DH; Ren, LL; Gu, DL,期刊:Gene, 页码:93-97 , 文章类型: Article,,卷期:2012年497-1]
- Recently, two genome-wide association studies in Asia identified gene polymorphisms known as rs4488809, rs9816619 in TP63 and rs2131877, rs952481 in C3orf21. It has been proposed that these polymorphisms are susceptibili...
- Polymorphisms of the insulin-like growth factor-binding protein 3 gene (IGFBP3) in gayal (Bos frontalis)
[作者:Xi, DM; Wu, M; Fan, YY; Liu, Q; Leng, J; Gou, X; Mao, HM; Deng, WD,期刊:Gene, 页码:98-102 , 文章类型: Article,,卷期:2012年497-1]
- The gene coding for insulin-like growth factor-binding protein 3 (IGFBP3) is important for regulation of growth, development and metabolism in mammals. The present investigation was conducted to study nucleotide polymorp...
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