- Pharmacogenomics and Personalized Use of Drugs
[作者:Wang, JF; Wei, DQ; Chou, KC,期刊:Current Topics in Medicinal Chemistry, 页码:1573-1579 , 文章类型: Review,,卷期:2008年8-18]
As the development of the Human Genome Project (HGP), the sequencing of whole human genome has been completed, and a series of human genes have been detected, both of which result in the naissance of pharmacogenomics....
- Applications of 2D Descriptors in Drug Design: A DRAGON Tale
[作者:Helguera, AM; Combes, RD; Gonzalez, MP; Cordeiro, MNDS,期刊:Current Topics in Medicinal Chemistry, 页码:1628-1655 , 文章类型: Review,,卷期:2008年8-18]
In order to minimize expensive drug failures, is essential to determine potential activity, toxicity and ADME problems as early as possible. In view of the large libraries of compounds now being handled by combinatori...
- Current Topics on Software Use in Medicinal Chemistry: Intellectual Property, Taxes, and Regulatory Issues
[作者:Duardo-Sanchez, A; Patlewicz, G; Lopez-Diaz, A,期刊:Current Topics in Medicinal Chemistry, 页码:1666-1675 , 文章类型: Review,,卷期:2008年8-18]
In recent times, there has been an increased use of software and computational models in Medicinal Chemistry, both for the prediction of effects such as drug-target interactions, as well as for the development of (Qua...
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