- Pulsatile shear stress increased mitochondrial membrane potential: Implication of Mn-SOD
[作者:Li, RS; Beebe, T; Cui, J; Rouhanizadeh, M; Ai, LS; Wang, P; Gundersen, M; Takabe, W; Hsiai, TK,期刊:Biochemical and Biophysical Research Communications, 页码:406-412 , 文章类型: Article,,卷期:2009年388-2]
- Mitochondrial dysfunction is intimately involved in cardiovascular diseases. Mitochondrial membrane potential (Delta Psi(m)) is coupled with oxidative phosphorylation to drive ATP synthesis. In this study, we examined th...
- The effect of interferon-beta on mouse neural progenitor cell survival and differentiation
[作者:Hirsch, M; Knight, J; Tobita, M; Soltys, J; Panitch, H; Mao-Draayer, Y,期刊:Biochemical and Biophysical Research Communications, 页码:181-186 , 文章类型: Article,,卷期:2009年388-2]
- Interferon-beta (IFN-beta) is a mainstay therapy for relapse-remitting multiple sclerosis (MS). However, the direct effects of IFN-beta on the central nervous system (CNS) are not well understood. To determine whether IF...
- TRIM31 interacts with p52(Shc) and inhibits Src-induced anchorage-independent growth
[作者:Watanabe, M; Tsukiyama, T; Hatakeyama, S,期刊:Biochemical and Biophysical Research Communications, 页码:422-427 , 文章类型: Article,,卷期:2009年388-2]
- Tripartite motif-containing protein (TRIM) family proteins are involved in a broad range of biological processes and, consistently, their alterations result in diverse pathological conditions such as genetic diseases, vi...
- Structural basis for the Helicobacter pylori-carcinogenic TNF-alpha-inducing protein
[作者:Tsuge, H; Tsurumura, T; Utsunomiya, H; Kise, D; Kuzuhara, T; Watanabe, T; Fujiki, H; Suganuma, M,期刊:Biochemical and Biophysical Research Communications, 页码:193-198 , 文章类型: Article,,卷期:2009年388-2]
- Stomach cancer is strongly associated with infection by Helicobacter pylori. In 2005, we identified a new H. pylori gene encoding a TNF-alpha inducing protein (Tip alpha) that acts as a carcinogenic factor. Tip alpha is ...
- Blockade of bradykinin B2 receptor more effectively reduces postischemic blood-brain barrier disruption and cytokines release than B1 receptor inhibition
[作者:Su, JJ; Cui, M; Tang, YP; Zhou, HG; Liu, L; Dong, Q,期刊:Biochemical and Biophysical Research Communications, 页码:205-211 , 文章类型: Article,,卷期:2009年388-2]
- Blood-brain barrier disruption and brain edema are detrimental in ischemic stroke. The kallikrein-kinin system appears to play an important role in the regulation of vascular permeability and is invoked in edema formatio...
- The evolutionary conserved gene C16orf35 encodes a nucleo-cytoplasmic protein that interacts with p73
[作者:Lunardi, A; Chiacchiera, F; D'Este, E; Carotti, M; Dal Ferro, M; Di Minin, G; Del Sal, G; Collavin, L,期刊:Biochemical and Biophysical Research Communications, 页码:428-433 , 文章类型: Article,,卷期:2009年388-2]
- C16orf35 is a highly conserved gene positioned upstream of the alpha-globins in humans and other vertebrates. The deduced protein is also highly conserved, it has no defined structural features or domains, and its functi...
- Splicing of intron 3 of human BACE requires the flanking introns 2 and 4
[作者:Annies, M; Stefani, M; Hueber, A; Fischer, F; Paganetti, P,期刊:Biochemical and Biophysical Research Communications, 页码:434-438 , 文章类型: Article,,卷期:2009年388-2]
- Regulation of proteolytic cleavage of the amyloid precursor protein by the aspartic protease BACE may occur by alternative splicing and the generation of enzymatically inactive forms. In fact, the presence of exonic dono...
- Anandamide increases swelling and reduces calcium sensitivity of mitochondria
[作者:Catanzaro, G; Rapino, C; Oddi, S; Maccarrone, M,期刊:Biochemical and Biophysical Research Communications, 页码:439-442 , 文章类型: Article,,卷期:2009年388-2]
- The endocannabinoid anandamide alters mitochondria-dependent signal transduction, thus controlling key cellular events like energy homeostasis and induction of apoptosis. Here, the ability of anandamide to directly affec...
- Dietary antioxidants interfere with Amplex Red-coupled-fluorescence assays
[作者:Serrano, J; Jove, M; Boada, J; Bellmunt, MJ; Pamplona, R; Portero-Otin, M,期刊:Biochemical and Biophysical Research Communications, 页码:443-449 , 文章类型: Article,,卷期:2009年388-2]
- Oxidation of Amplex Red by hydrogen peroxide in the presence of horseradish peroxidase (HRP) gives rise to an intensely colour product, resorufin. This reaction has been frequently employed for measurements based onenzym...
- Hypoxia inhibits maturation and trafficking of hERG K+ channel protein: Role of Hsp90 and ROS
[作者:Nanduri, J; Bergson, P; Wang, N; Ficker, E; Prabhakar, NR,期刊:Biochemical and Biophysical Research Communications, 页码:212-216 , 文章类型: Article,,卷期:2009年388-2]
- We previously reported that reactive oxygen species (ROS) generated during hypoxia decrease hERG current density and protein expression in HEK cells stably expressing hERG protein. In the present study, we investigated t...
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