- Dual-targeting of alpha(v)beta(3) and galectin-1 improves the specificity of paramagnetic/fluorescent liposomes to tumor endothelium in vivo
[作者：Kluza, E; Jacobs, I; Hectors, SJCG; Mayo, KH; Griffioen, AW; Strijkers, GJ; Nicolay, K,期刊：Journal of controlled release, 页码：207-214 , 文章类型： Article，,卷期：2012年158-2]
- Molecular imaging of angiogenesis requires a highly specific and efficient contrast agent for targeting activated endothelium. We have previously demonstrated that paramagnetic and fluorescent liposomes functionalized wi...
- Engineered cartilage via self-assembled hMSC sheets with incorporated biodegradable gelatin microspheres releasing transforming growth factor-beta 1
[作者：Solorio, LD; Vieregge, EL; Dhami, CD; Dang, PN; Alsberg, E,期刊：Journal of controlled release, 页码：224-232 , 文章类型： Article，,卷期：2012年158-2]
- Self-assembling cell sheets have shown great potential for use in cartilage tissue engineering applications, as they provide an advantageous environment for the chondrogenic induction of human mesenchymal stem cells (hMS...
- Polyelectrolyte LbL microcapsules versus PLGA microparticles for immunization with a protein antigen
[作者：De Temmerman, ML; Rejman, J; Vandenbroucke, RE; De Koker, S; Libert, C; Grooten, J; Demeester, J; Gander, B; De Smedt, SC,期刊：Journal of controlled release, 页码：233-239 , 文章类型： Article，,卷期：2012年158-2]
- The transition from organism-based traditional vaccines to the use of safer subunit vaccines has implemented the use of adjuvants to enhance immunogenicity. This study compares the potential of two types of polymeric mic...
- Transferrin conjugation confers mucosal molecular targeting to a model HIV-1 trimeric gp140 vaccine antigen
[作者：Mann, JFS; Stieh, D; Klein, K; de Stegmann, DSM; Cranage, MP; Shattock, RJ; McKay, PF,期刊：Journal of controlled release, 页码：240-249 , 文章类型： Article，,卷期：2012年158-2]
- The generation of effective immune responses by mucosal vaccination without the use of inflammatory adjuvants, that compromise the epithelial barrier and recruit new cellular targets, is a key goal of vaccines designed t...
- A physical mechanism to explain the delivery of chemical penetration enhancers into skin during transdermal sonophoresis - Insight into the observed synergism
[作者：Polat, BE; Deen, WM; Langer, R; Blankschtein, D,期刊：Journal of controlled release, 页码：250-260 , 文章类型： Article，,卷期：2012年158-2]
- The synergism between low-frequency sonophoresis (LFS) and chemical penetration enhancers (CPEs), especially surfactants, in transdermal enhancement has been investigated extensively since this phenomenon was first obser...
- Versatile cationic lipids for siRNA delivery
[作者：Sparks, J; Slobodkin, G; Matar, M; Congo, R; Ulkoski, D; Rea-Ramsey, A; Pence, C; Rice, J; McClure, D; Polach, KJ; Brunhoeber, E; Wilkinson, L; Wallace, K; Anwer, K; Fewell, JG,期刊：Journal of controlled release, 页码：269-276 , 文章类型： Article，,卷期：2012年158-2]
- Exploitation of the RNA interference (RNAi) pathway offers the promise of new and effective therapies for a wide variety of diseases. Clinical development of new drugs based on this platform technology is still limited, ...
- Tat(48-60) peptide amino acid sequence is not unique in its cell penetrating properties and cell-surface glycosaminoglycans inhibit its cellular uptake
[作者：Subrizi, A; Tuominen, E; Bunker, A; Rog, T; Antopolsky, M; Urtti, A,期刊：Journal of controlled release, 页码：277-285 , 文章类型： Article，,卷期：2012年158-2]
- Biomolecules and drug delivery agents, such as liposomes, are often delivered intracellularly with help of cell penetrating peptides (CPPs) and, in particular, Tat peptide. Tat peptide acts as a membrane shuttle; the str...
- Targeted delivery of oligonucleotides into tumor-associated macrophages for cancer immunotherapy
[作者：Huang, Z; Zhang, ZP; Jiang, YC; Zhang, DC; Chen, JN; Dong, L; Zhang, JF,期刊：Journal of controlled release, 页码：286-292 , 文章类型： Article，,卷期：2012年158-2]
- Tumor-associated macrophages (TAMs) have been proven to be a driving force in the initiation, proliferation, metastasis and angiogenesis of various tumors. Specifically, alterations in the functions of TAMs exhibited inh...
- Effective endogenous gene silencing mediated by pH responsive peptides proceeds via multiple pathways
[作者：Lam, JKW; Liang, W; Lan, Y; Chaudhuri, P; Chow, MYT; Witt, K; Kudsiova, L; Mason, AJ,期刊：Journal of controlled release, 页码：293-303 , 文章类型： Article，,卷期：2012年158-2]
- Cationic amphipathic histidine rich peptides possess high plasmid DNA and siRNA delivery capabilities. To further understand the pH responsive siRNA delivery process and evaluate the capabilities of such peptides we have...
- Photothermal-chemotherapy with doxorubicin-loaded hollow gold nanospheres: A platform for near-infrared light-trigged drug release
[作者：You, J; Zhang, R; Zhang, GD; Zhong, M; Liu, Y; Van Pelt, CS; Liang, D; Wei, W; Sood, AK; Li, C,期刊：Journal of controlled release, 页码：319-328 , 文章类型： Article，,卷期：2012年158-2]
- Photothermal ablation (PTA) is an emerging technique that uses near-infrared (NIR) laser light-generated heat to destroy tumor cells. However, complete eradication of tumor cells with PTA is difficult because of uneven h...
- Characterization of novel spray-dried polymeric particles for controlled pulmonary drug delivery
[作者：Beck-Broichsitter, M; Schweiger, C; Schmehl, T; Gessler, T; Seeger, W; Kissel, T,期刊：Journal of controlled release, 页码：329-335 , 文章类型： Article，,卷期：2012年158-2]
- Numerous studies have addressed the controlled pulmonary drug delivery properties of colloidal particles. However, only scant information on the potential of spray-drying for submicron particle preparation is available. ...
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