- Investigational EGFR-targeted therapy in head and neck squamous cell carcinoma
[作者:Cassell, A; Grandis, JR,期刊:Expert opinion on investigational drugs, 页码:709-722 , 文章类型: Review,,卷期:2010年19-6]
- Importance of the field: EGFR is an established therapeutic target in head and neck squamous cell carcinoma (HNSCC). The EGFR-targeting monoclonal antibody cetuximab (Erbitux (TM), Imclone Systems, Inc., Branchburg, USA)...
- MESNA for chemically assisted tissue dissection
[作者:Casale, M; Martino, A; Salvinelli, F; Trombetta, M; Denaro, V,期刊:Expert opinion on investigational drugs, 页码:699-707 , 文章类型: Review,,卷期:2010年19-6]
- Importance of the field: To date, surgical dissection is based only on mechanical forces. The use of a chemical product that is able to ease tissue dissection represents an important advance. MESNA (sodium-2-mercaptoetha...
- Investigational approaches to therapies for idiopathic pulmonary fibrosis
[作者:Gomer, RH; Lupher, ML,期刊:Expert opinion on investigational drugs, 页码:737-745 , 文章类型: Review,,卷期:2010年19-6]
- Importance of the field: In fibrosing diseases, scar tissue begins to replace normal tissue, causing tissue dysfunction. For instance, in lung fibrosis, foci of what resembles scar tissue form in the lungs, impeding the ...
- New-generation 5-HT4 receptor agonists: potential for treatment of gastrointestinal motility disorders
[作者:Manabe, N; Wong, BS; Camilleri, M,期刊:Expert opinion on investigational drugs, 页码:765-775 , 文章类型: Review,,卷期:2010年19-6]
- Importance of the field: Gastrointestinal (GI) dysmotility is an important mechanism in functional GI disorders (FGIDs) including constipation, irritable bowel syndrome, functional dyspepsia, and gastroparesis. 5-hydroxy...
- AICA-riboside (acadesine), an activator of AMP-activated protein kinase with potential for application in hematologic malignancies (vol 19, pg 571, 2010)
[作者:Van den Neste, E; Van den Berghe, G; Bontemps, F,期刊:Expert opinion on investigational drugs, 页码:807-807 , 文章类型: Correction,,卷期:2010年19-6]
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