- Analogues of sigma Receptor Ligand 1-Cyclohexyl-4[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]pip erazine (PB28) with Added Polar Functionality and Reduced Lipophilicity for Potential Use as Positron Emission Tomography Radiotracers
[作者:ABATE CARMEN; NISO MAURO; LACIVITA ENZA; MOSIER PHILIP D; TOSCANO ANNAMARIA; PERRONE ROBERTO,期刊:Journal of Medicinal Chemistry, 页码:1022-1032 , 文章类型: Article,,卷期:2011年54-4]
- 1-Cyclohexyl-4[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]pip erazine 1 (PB28) represents an excellent lead candidate for therapeutic and/or diagnostic applications in oncology. However, because its utility is...
- Biotin Ergopeptide Probes for Dopamine Receptors
[作者:VENDRELL MARC; MOLERO ANABEL; GONZALEZ SERGIO; PEREZCAPOTE KAMIL; LLUIS CARME; MCCORMICK PETER J; FRANCO RAFAEL; CORTES ANTONI; CASADO VICENT; ALBERICIO FERNANDO; ROYO MIRIAM,期刊:Journal of Medicinal Chemistry, 页码:1080-1090 , 文章类型: Article,,卷期:2011年54-4]
- The incorporation of chemical modifications into the structure of bioactive compounds is often difficult because the biological properties of the new molecules must be retained with respect to the native ligand. Ergopept...
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