- Specific Lineage-Priming of Bone Marrow Mesenchymal Stem Cells Provides the Molecular Framework for Their Plasticity
[作者:Delorme, B; Ringe, J; Pontikoglou, C; Gaillard, J; Langonne, A; Sensebe, L; Noel, D; Jorgensen, C; Haupl, T; Charbord, P,期刊:Stem Cells, 页码:1142-1151 , 文章类型: Article,,卷期:2009年27-5]
- Lineage-priming is a molecular model of stem cell (SC) differentiation in which proliferating SCs express a subset of genes associated to the differentiation pathways to which they can commit. This concept has been devel...
- Precursors with Glial Fibrillary Acidic Protein Promoter Activity Transiently Generate GABA Interneurons in the Postnatal Cerebellum
[作者:Silbereis, J; Cheng, E; Ganat, YM; Ment, LR; Vaccarino, FM,期刊:Stem Cells, 页码:1152-1163 , 文章类型: Article,,卷期:2009年27-5]
- Neural stem or progenitor cells (NSC/NPCs) able to generate the different neuron and glial cell types of the cerebellum have been isolated in vitro, but their identity and location in the intact cerebellum are unclear. H...
- Age-Dependent Depletion of Human Skin-Derived Progenitor Cells
[作者:Gago, N; Perez-Lopez, V; Sanz-Jaka, JP; Cormenzana, P; Eizaguirre, I; Bernad, A; Izeta, A,期刊:Stem Cells, 页码:1164-1172 , 文章类型: Article,,卷期:2009年27-5]
- A major unanswered question in autologous cell therapy is the appropriate timing for cell isolation. Many of the putative target diseases arise with old age and previous evidence, mainly from animal models, suggests that...
- Nuclear Factor I Isoforms Regulate Gene Expression During the Differentiation of Human Neural Progenitors to Astrocytes
[作者:Wilczynska, KM; Singh, SK; Adams, B; Bryan, L; Rao, RR; Valerie, K; Wright, S; Griswold-Prenner, I; Kordula, T,期刊:Stem Cells, 页码:1173-1181 , 文章类型: Article,,卷期:2009年27-5]
- Even though astrocytes are critical for both normal brain functions and the development and progression of neuropathological states, including neuroinflammation associated with neurodegenerative diseases, the mechanisms ...
- Pituitary Progenitor Cells Tracked Down by Side Population Dissection
[作者:Chen, JH; Gremeaux, L; Fu, QL; Liekens, D; Van Laere, S; Vankelecom, H,期刊:Stem Cells, 页码:1182-1195 , 文章类型: Article,,卷期:2009年27-5]
- Sca1(high) subset within the SP, stem cell growth factors that induce SP expansion, affect transcription of embryonic factors, suggesting impact on a developmental program that unfolds within this SP compartment. Non-Sca...
- Human Fetal Auditory Stem Cells Can Be Expanded In Vitro and Differentiate Into Functional Auditory Neurons and Hair Cell-Like Cells
[作者:Chen, W; Johnson, SL; Marcotti, W; Andrews, PW; Moore, HD; Rivolta, MN,期刊:Stem Cells, 页码:1196-1204 , 文章类型: Article,,卷期:2009年27-5]
- In the quest to develop the tools necessary for a cell-based therapy for deafness, a critical step is to identify a suitable stem cell population. Moreover, the lack of a self-renovating model system for the study of cel...
- Stem Cells, Multiorgan Failure in Radiation Emergency Medical Preparedness: A US/European Consultation Workshop
[作者:Fliedner, TM; Chao, NJ; Bader, JL; Boettger, A; Case, C; Chute, J; Confer, DL; Ganser, A; Gorin, NC; Gourmelon, P; Graessle, DH; Krawisz, R; Meineke, V; Niederwieser, D; Port, M; Powles, R; Sirohi, B; Weinstock, DM; Wiley, A; Coleman, CN,期刊:Stem Cells, 页码:1205-1211 , 文章类型: Article,,卷期:2009年27-5]
- The concern of the public regarding terrorist actions involving nuclear emergencies resulted in the reopening of the discussion regarding the best ways to cope with the inevitable health impairments. Medical experts from...
- Blockade of Peroxynitrite-Induced Neural Stem Cell Death in the Acutely Injured Spinal Cord by Drug-Releasing Polymer
[作者:Yu, D; Neeley, WL; Pritchard, CD; Slotkin, JR; Woodard, EJ; Langer, R; Teng, YD,期刊:Stem Cells, 页码:1212-1222 , 文章类型: Article,,卷期:2009年27-5]
- Therapeutic impact of neural stem cells (NSCs) for acute spinal cord injury (SCI) has been limited by the rapid loss of donor cells. Neuroinflammation is likely the cause. As there are close temporal-spatial correlations...
- Functional Evidence that the Self-Renewal Gene NANOG Regulates Human Tumor Development
[作者:Jeter, CR; Badeaux, M; Choy, G; Chandra, D; Patrawala, L; Liu, C; Calhoun-Davis, T; Zaehres, H; Daley, GQ; Tang, DG,期刊:Stem Cells, 页码:993-1005 , 文章类型: Article,,卷期:2009年27-5]
- Tumor development has long been known to resemble abnormal embryogenesis. The embryonic stem cell (ESC) self-renewal gene NANOG is purportedly expressed by some epithelial cancer cells but a causal role in tumor developm...
- Identification of Gastric Cancer Stem Cells Using the Cell Surface Marker CD44
[作者:Takaishi, S; Okumura, T; Tu, SP; Wang, SSW; Shibata, W; Vigneshwaran, R; Gordon, SAK; Shimada, Y; Wang, TC,期刊:Stem Cells, 页码:1006-1020 , 文章类型: Article,,卷期:2009年27-5]
- Cancer stem cells (CSCs) have been defined as a unique subpopulation in tumors that possess the ability to initiate tumor growth and sustain tumor self-renewal. Although the evidence has been provided to support the exis...
- Characterization of Dendritic Cells and Macrophages Generated by Directed Differentiation from Mouse Induced Pluripotent Stem Cells
[作者:Senju, S; Haruta, M; Matsunaga, Y; Fukushima, S; Ikeda, T; Takahashi, K; Okita, K; Yamanaka, S; Nishimura, Y,期刊:Stem Cells, 页码:1021-1031 , 文章类型: Article,,卷期:2009年27-5]
- Methods have been established to generate dendritic cells (DCs) from mouse and human embryonic stem (ES) cells. We designated them as ES-DCs and mouse models have demonstrated the induction of anti-cancer immunity and pr...
- Polycistronic Lentiviral Vector for "Hit and Run'' Reprogramming of Adult Skin Fibroblasts to Induced Pluripotent Stem Cells
[作者:Chang, CW; Lai, YS; Pawlik, KM; Liu, K; Sun, CW; Li, C; Schoeb, TR; Townes, TM,期刊:Stem Cells, 页码:1042-1049 , 文章类型: Article,,卷期:2009年27-5]
- We report the derivation of induced pluripotent stem (iPS) cells from adult skin fibroblasts using a single, polycistronic lentiviral vector encoding the reprogramming factors Oct4, Sox2, and Klf4. Porcine teschovirus-1 ...
- CD30 Expression Reveals that Culture Adaptation of Human Embryonic Stem Cells Can Occur Through Differing Routes
[作者:Harrison, NJ; Barnes, J; Jones, M; Baker, D; Gokhale, PJ; Andrews, PW,期刊:Stem Cells, 页码:1057-1065 , 文章类型: Article,,卷期:2009年27-5]
- Human embryonic stem cells undergo adaptive changes that can increase their growth capacity upon prolonged culture in vitro. This is frequently associated with nonrandom karyotypic changes, commonly involving amplificati...
- Differential Requirement for Nucleostemin in Embryonic Stem Cell and Neural Stem Cell Viability
[作者:Nomura, J; Maruyama, M; Katano, M; Kato, H; Zhang, JX; Masui, S; Mizuno, Y; Okazaki, Y; Nishimoto, M; Okuda, A,期刊:Stem Cells, 页码:1066-1076 , 文章类型: Article,,卷期:2009年27-5]
- Stem cells have the remarkable ability to self-renew and to generate multiple cell types. Nucleostemin is one of proteins that are enriched in many types of stem cells. Targeted deletion of nucleostemin in the mouse resu...
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