- Chemoprevention of Breast Cancer by Fish Oil in Preclinical Models: Trials and Tribulations
[作者:Signori, C; El-Bayoumy, K; Russo, J; Thompson, HJ; Richie, JP; Hartman, TJ; Manni, A,期刊:Cancer research, 页码:6091-6096 , 文章类型: Review,,卷期:2011年71-19]
- Despite the perception that omega-3 fatty acids (n-3 FA) protect against breast cancer, epidemiologic studies have yielded inconsistent results. Although preclinical data have been, in general, more supportive of a prote...
- IDIBELL Cancer Conference on Metastasis and Angiogenesis
[作者:Carmona, FJ; Esteller, M,期刊:Cancer research, 页码:6097-6101 , 文章类型: Article,,卷期:2011年71-19]
- The IDIBELL Cancer Conference (ICC) on Metastasis and Angiogenesis was held in Barcelona, Spain, on May 26-27, 2011. The program content was developed by Dr. Manel Esteller, director of the Cancer Epigenetics and Biology...
- Keystone Symposia 40th Season: MicroRNAs and Noncoding RNAs in Cancer
[作者:Wasik, KA; Rebbeck, CA,期刊:Cancer research, 页码:6102-6105 , 文章类型: Article,,卷期:2011年71-19]
- This year's 40th season of Keystone symposia meetings was held in Banff, Alberta, Canada, on February 11-16 and sponsored by Astellas Pharma and Regulus Therapeutics. The meeting was organized by Gregory Hannon, Curtis H...
- Downregulation of RBMS3 Is Associated with Poor Prognosis in Esophageal Squamous Cell Carcinoma
[作者:Li, Y; Chen, LL; Nie, CJ; Zeng, TT; Liu, HB; Mao, XY; Qin, YR; Zhu, YH; Fu, L; Guan, XY,期刊:Cancer research, 页码:6106-6115 , 文章类型: Article,,卷期:2011年71-19]
- Deletions on chromosome 3p occur often in many solid tumors, including esophageal squamous cell carcinoma (ESCC), suggesting the existence at this location of one or more tumor suppressor genes (TSG). In this study, we c...
- Effects of Photoacoustic Imaging and Photothermal Ablation Therapy Mediated by Targeted Hollow Gold Nanospheres in an Orthotopic Mouse Xenograft Model of Glioma
[作者:Lu, W; Melancon, MP; Xiong, CY; Huang, Q; Elliott, A; Song, SL; Zhang, R; Flores, LG; Gelovani, JG; Wang, LHV; Ku, G; Stafford, RJ; Li, C,期刊:Cancer research, 页码:6116-6121 , 文章类型: Article,,卷期:2011年71-19]
- Advancements in nanotechnology have made it possible to create multifunctional nanostructures that can be used simultaneously to image and treat cancers. For example, hollow gold nanospheres (HAuNS) have been shown to ge...
- Resuscitating Cancer Immunosurveillance: Selective Stimulation of DLL1-Notch Signaling in T cells Rescues T-cell Function and Inhibits Tumor Growth
[作者:Huang, YH; Lin, LP; Shanker, A; Malhotra, A; Yang, L; Dikov, MM; Carbone, DP,期刊:Cancer research, 页码:6122-6131 , 文章类型: Article,,卷期:2011年71-19]
- Deficiencies in immune function that accumulate during cancer immunoediting lead to a progressive escape from host immunosurveillance. Therapies that correct or overcome these defects could have a powerful impact on canc...
- FLT3 Ligand Enhances the Cancer Therapeutic Potency of Naked RNA Vaccines
[作者:Kreiter, S; Diken, M; Selmi, A; Diekmann, J; Attig, S; Husemann, Y; Koslowski, M; Huber, C; Tureci, O; Sahin, U,期刊:Cancer research, 页码:6132-6142 , 文章类型: Article,,卷期:2011年71-19]
- Intranodal immunization with antigen-encoding naked RNA may offer a simple and safe approach to induce antitumor immunity. RNA taken up by nodal dendritic cells (DC) coactivates toll-like receptor (TLR) signaling that wi...
- Early Detection of Tumor Cells by Innate Immune Cells Leads to T(reg) Recruitment through CCL22 Production by Tumor Cells
[作者:Faget, J; Biota, C; Bachelot, T; Gobert, M; Treilleux, I; Goutagny, N; Durand, I; Leon-Goddard, S; Blay, JY; Caux, C; Menetrier-Caux, C,期刊:Cancer research, 页码:6143-6152 , 文章类型: Article,,卷期:2011年71-19]
- In breast carcinomas, patient survival seems to be negatively affected by the recruitment of regulatory T cells (T(reg)) within lymphoid aggregates by CCL22. However, the mechanisms underpinning this process, which may b...
- Proto-oncogene PBF/PTTG1IP Regulates Thyroid Cell Growth and Represses Radioiodide Treatment
[作者:Read, ML; Lewy, GD; Fong, JCW; Sharma, N; Seed, RI; Smith, VE; Gentilin, E; Warfield, A; Eggo, MC; Knauf, JA; Leadbeater, WE; Watkinson, JC; Franklyn, JA; Boelaert, K; McCabe, CJ,期刊:Cancer research, 页码:6153-6164 , 文章类型: Article,,卷期:2011年71-19]
- Pituitary tumor transforming gene (PTTG)-binding factor (PBF or PTTG1IP) is a little characterized proto-oncogene that has been implicated in the etiology of breast and thyroid tumors. In this study, we created a murine ...
- miR-375 Is Activated by ASH1 and Inhibits YAP1 in a Lineage-Dependent Manner in Lung Cancer
[作者:Nishikawa, E; Osada, H; Okazaki, Y; Arima, C; Tomida, S; Tatematsu, Y; Taguchi, A; Shimada, Y; Yanagisawa, K; Yatabe, Y; Toyokuni, S; Sekido, Y; Takahashi, T,期刊:Cancer research, 页码:6165-6173 , 文章类型: Article,,卷期:2011年71-19]
- Lung cancers with neuroendocrine (NE) features are often very aggressive but the underlying molecular mechanisms remain elusive. The transcription factor ASH1/ASCL1 is a master regulator of pulmonary NE cell development ...
- Cyclin D1 and Cdk4 Mediate Development of Neurologically Destructive Oligodendroglioma
[作者:Ciznadija, D; Liu, YH; Pyonteck, SM; Holland, EC; Koff, A,期刊:Cancer research, 页码:6174-6183 , 文章类型: Article,,卷期:2011年71-19]
- Although the molecular changes that characterize gliomas have been studied, the pathogenesis of tumor development remains unclear. p21 contributes to gliomagenesis by stabilizing cyclin D1-cdk4 kinase complexes, suggesti...
- Wnt5a Suppresses Epithelial Ovarian Cancer by Promoting Cellular Senescence
[作者:Bitler, BG; Nicodemus, JP; Li, H; Cai, Q; Wu, H; Hua, X; Li, TY; Birrer, MJ; Godwin, AK; Cairns, P; Zhang, RG,期刊:Cancer research, 页码:6184-6194 , 文章类型: Article,,卷期:2011年71-19]
- Epithelial ovarian cancer (EOC) remains the most lethal gynecologic malignancy in the United States. Thus, there is an urgent need to develop novel therapeutics for this disease. Cellular senescence is an important tumor...
- Genome-wide Methylation Analysis Identifies Genes Specific to Breast Cancer Hormone Receptor Status and Risk of Recurrence
[作者:Fackler, MJ; Umbricht, CB; Williams, D; Argani, P; Cruz, LA; Merino, VF; Teo, WW; Zhang, Z; Huang, P; Visvananthan, K; Marks, J; Ethier, S; Gray, JW; Wolff, AC; Cope, LM; Sukumar, S,期刊:Cancer research, 页码:6195-6207 , 文章类型: Article,,卷期:2011年71-19]
- To better understand the biology of hormone receptor-positive and -negative breast cancer and to identify methylated gene markers of disease progression, we carried out a genome-wide methylation array analysis on 103 pri...
- MicroRNA-708 Induces Apoptosis and Suppresses Tumorigenicity in Renal Cancer Cells
[作者:Saini, S; Yamamura, S; Majid, S; Shahryari, V; Hirata, H; Tanaka, Y; Dahiya, R,期刊:Cancer research, 页码:6208-6219 , 文章类型: Article,,卷期:2011年71-19]
- Cancer pathogenesis is restricted by stresses that compromise cell division and survival. In this study, we identify miR-708, a little studied member of a set of microRNAs that have been implicated in stress control, as ...
- A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function
[作者:Gasparre, G; Kurelac, I; Capristo, M; Iommarini, L; Ghelli, A; Ceccarelli, C; Nicoletti, G; Nanni, P; De Giovanni, C; Scotlandi, K; Betts, CM; Carelli, V; Lollini, PL; Romeo, G; Rugolo, M; Porcelli, AM,期刊:Cancer research, 页码:6220-6229 , 文章类型: Article,,卷期:2011年71-19]
- The oncogenic versus suppressor roles of mitochondrial genes have long been debated. Peculiar features of mitochondrial genetics such as hetero/homoplasmy and mutation threshold are seldom taken into account in this deba...
- MicroRNA-32 Upregulation by 1,25-Dihydroxyvitamin D(3) in Human Myeloid Leukemia Cells Leads to Bim Targeting and Inhibition of AraC-Induced Apoptosis
[作者:Gocek, E; Wang, XN; Liu, XP; Liu, CG; Studzinski, GP,期刊:Cancer research, 页码:6230-6239 , 文章类型: Article,,卷期:2011年71-19]
- 1,25-Dihydroxyvitamin D(3) (1,25D) used to treat human acute myeloid leukemia (AML) cells induces features of normal monocytes, but the mechanisms underlying this response are not fully understood. We hypothesized that o...
|