- Long Noncoding RNA, Polycomb, and the Ghosts Haunting INK4b-ARF-INK4a Expression
[作者：Aguilo, F; Zhou, MM; Walsh, MJ,期刊：Cancer research, 页码：5365-5369 , 文章类型： Review，,卷期：2011年71-16]
- Polycomb group proteins (PcG) function as transcriptional repressors of gene expression. The important role of PcG in mediating repression of the INK4b-ARF-INK4a locus, by directly binding to the long noncoding RNA (lncR...
- B-Myb, Cancer, Senescence, and MicroRNAs
[作者：Martinez, I; DiMaio, D,期刊：Cancer research, 页码：5370-5373 , 文章类型： Review，,卷期：2011年71-16]
- The transcription factor B-Myb plays a critical role in regulating gene expression and is implicated in controlling carcinogenesis and cellular senescence. Transcription of the B-Myb gene is regulated by retinoblastoma p...
- Indirubins Decrease Glioma Invasion by Blocking Migratory Phenotypes in Both the Tumor and Stromal Endothelial Cell Compartments
[作者：Williams, SP; Nowicki, MO; Liu, F; Press, R; Godlewski, J; Abdel-Rasoul, M; Kaur, B; Fernandez, SA; Chiocca, EA; Lawler, SE,期刊：Cancer research, 页码：5374-5380 , 文章类型： Article，,卷期：2011年71-16]
- Invasion and proliferation in neoplasia require the cooperation of tumor cell and endothelial compartments. Glycogen synthase kinase-3 (GSK-3) is increasingly recognized as a major contributor to signaling pathways that ...
- Imatinib Sensitivity in BCR-ABL1-Positive Chronic Myeloid Leukemia Cells Is Regulated by the Remaining Normal ABL1 Allele
[作者：Virgili, A; Koptyra, M; Dasgupta, Y; Glodkowska-Mrowka, E; Stoklosa, T; Nacheva, EP; Skorski, T,期刊：Cancer research, 页码：5381-5386 , 文章类型： Article，,卷期：2011年71-16]
- Chronic myeloid leukemia in chronic phase (CML-CP) cells that harbor oncogenic BCR-ABL1 and normal ABL1 allele often become resistant to the ABL1 kinase inhibitor imatinib. Here, we report that loss of the remaining norm...
- TMPRSS2-ERG-Mediated Feed-Forward Regulation of Wild-Type ERG in Human Prostate Cancers
[作者：Mani, RS; Iyer, MK; Cao, Q; Brenner, JC; Wang, L; Ghosh, A; Cao, XH; Lonigro, RJ; Tomlins, SA; Varambally, S; Chinnaiyan, AM,期刊：Cancer research, 页码：5387-5392 , 文章类型： Article，,卷期：2011年71-16]
- Recurrent gene fusions involving ETS family genes are a distinguishing feature of human prostate cancers, with TMPRSS2-ERG fusions representing the most common subtype. The TMPRSS2-ERG fusion transcript and its splice va...
- IL-18 Induces PD-1-Dependent Immunosuppression in Cancer
[作者：Terme, M; Ullrich, E; Aymeric, L; Meinhardt, K; Desbois, M; Delahaye, N; Viaud, S; Ryffel, B; Yagita, H; Kaplanski, G; Prevost-Blondel, A; Kato, M; Schultze, JL; Tartour, E; Kroemer, G; Chaput, N; Zitvogel, L,期刊：Cancer research, 页码：5393-5399 , 文章类型： Article，,卷期：2011年71-16]
- Immunosuppressive cytokines subvert innate and adaptive immune responses during cancer progression. The inflammatory cytokine interleukin-18 (IL-18) is known to accumulate in cancer patients, but its pathophysiological r...
- Comparing Signaling Networks between Normal and Transformed Hepatocytes Using Discrete Logical Models
[作者：Saez-Rodriguez, J; Alexopoulos, LG; Zhang, MS; Morris, MK; Lauffenburger, DA; Sorger, PK,期刊：Cancer research, 页码：5400-5411 , 文章类型： Article，,卷期：2011年71-16]
- Substantial effort in recent years has been devoted to constructing and analyzing large-scale gene and protein networks on the basis of "omic" data and literature mining. These interaction graphs provide valuable insight...
- Profound Coordinated Alterations of Intratumoral NK Cell Phenotype and Function in Lung Carcinoma
[作者：Platonova, S; Cherfils-Vicini, J; Damotte, D; Crozet, L; Vieillard, V; Validire, P; Andre, P; Dieu-Nosjean, MC; Alifano, M; Regnard, JF; Fridman, WH; Sautes-Fridman, C; Cremer, I,期刊：Cancer research, 页码：5412-5422 , 文章类型： Article，,卷期：2011年71-16]
- Both the innate and adaptive immune systems contribute to tumor immunosurveillance in mice and humans; however, there is a paucity of direct evidence of a role for natural killer (NK) cells in this important process. In ...
- Quantitative and Functional Alterations of Plasmacytoid Dendritic Cells Contribute to Immune Tolerance in Ovarian Cancer
[作者：Labidi-Galy, SI; Sisirak, V; Meeus, P; Gobert, M; Treilleux, I; Bajard, A; Combes, JD; Faget, J; Mithieux, F; Cassignol, A; Tredan, O; Durand, I; Menetrier-Caux, C; Caux, C; Blay, JY; Ray-Coquard, I; Bendriss-Vermare, N,期刊：Cancer research, 页码：5423-5434 , 文章类型： Article，,卷期：2011年71-16]
- In ovarian cancer, the immune system fails to eradicate established tumors partly due to the induction of immune tolerance within tumor microenvironment. In this study, we investigated the contribution of plasmacytoid de...
- A Novel Tumor Antigen Derived from Enhanced Degradation of Bax Protein in Human Cancers
[作者：Nunes, CT; Miners, KL; Dolton, G; Pepper, C; Fegan, C; Mason, MD; Man, S,期刊：Cancer research, 页码：5435-5444 , 文章类型： Article，,卷期：2011年71-16]
- Cancer cells frequently exhibit defects in apoptosis, which contribute to increased survival and chemotherapeutic resistance. For example, genetic mutations or abnormal proteasomal degradation can reduce expression of Ba...
- Maximal T Cell-Mediated Antitumor Responses Rely upon CCR5 Expression in Both CD4(+) and CD8(+) T Cells
[作者：Gonzalez-Martin, A; Gomez, L; Lustgarten, J; Mira, E; Manes, S,期刊：Cancer research, 页码：5455-5466 , 文章类型： Article，,卷期：2011年71-16]
- Immune responses against cancer rely upon leukocyte trafficking patterns that are coordinated by chemokines. CCR5, the receptor for chemotactic chemokines MIP1alpha, MIP1beta, and RANTES (CCL3, CCL4, CCL5), exerts major ...
- TLR4 Engagement during TLR3-Induced Proinflammatory Signaling in Dendritic Cells Promotes IL-10-Mediated Suppression of Antitumor Immunity
[作者：Bogunovic, D; Manches, O; Godefroy, E; Yewdall, A; Gallois, A; Salazar, AM; Marie, I; Levy, DE; Bhardwaj, N,期刊：Cancer research, 页码：5467-5476 , 文章类型： Article，,卷期：2011年71-16]
- Toll-like receptor (TLR) agonists are promising adjuvants for immune therapy of cancer, but their potential efficacy as single or combinatorial agents has yet to be fully evaluated. Here, we report that among all TLR ago...
- Api6/AIM/Sp alpha/CD5L Overexpression in Alveolar Type II Epithelial Cells Induces Spontaneous Lung Adenocarcinoma
[作者：Li, Y; Qu, P; Wu, LY; Li, BL; Du, H; Yan, C,期刊：Cancer research, 页码：5488-5499 , 文章类型： Article，,卷期：2011年71-16]
- Chronic inflammation is an important contributor to the development of lung cancers, one of the most common malignancies worldwide, but the underlying molecular mechanisms of inflammation that specifically cue cancer ris...
- VHL Gene Mutations and Their Effects on Hypoxia Inducible Factor HIF alpha: Identification of Potential Driver and Passenger Mutations
[作者：Rechsteiner, MP; von Teichman, A; Nowicka, A; Sulser, T; Schraml, P; Moch, H,期刊：Cancer research, 页码：5500-5511 , 文章类型： Article，,卷期：2011年71-16]
- Mutations of the von Hippel-Lindau (VHL) gene are frequent in clear cell renal cell carcinomas (ccRCC). Nonsense and frameshift mutations abrogate the function of the VHL protein (pVHL), whereas missense mutations can ha...
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