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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共30条记录   Systemic DNA Damage Related to Cancer [作者：Martin, OA; Redon, CE; Nakamura, AJ; Dickey, JS; Georgakilas, AG; Bonner, WM,期刊：Cancer research, 页码：3437-3441 , 文章类型： Review，,卷期：2011年71-10] The importance of bystander effects is becoming more appreciated, as studies show they may affect the course of cancer and other chronic diseases. The term "bystander effects" refers to changes in naive cells sharing the... National Cancer Institute Prostate Cancer Genetics Workshop [作者：Catalona, WJ; Bailey-Wilson, JE; Camp, NJ; Chanock, SJ; Cooney, KA; Easton, DF; Eeles, RA; FitzGerald, LM; Freedman, ML; Gudmundsson, J; Kittles, RA; Margulies, EH; McGuire, BB; Ostrander, EA; Rebbeck, TR; Stanford, JL; Thibodeau, SN; Witte, JS; Isaacs, W,期刊：Cancer research, 页码：3442-3446 , 文章类型： Article，,卷期：2011年71-10] Compelling evidence supports a genetic component to prostate cancer susceptibility and aggressiveness. Recent genome-wide association studies have identified more than 30 single-nucleotide polymorphisms associated with p... Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer [作者：Birkbak, NJ; Eklund, AC; Li, QY; McClelland, SE; Endesfelder, D; Tan, P; Tan, IB; Richardson, AL; Szallasi, Z; Swanton, C,期刊：Cancer research, 页码：3447-3452 , 文章类型： Article，,卷期：2011年71-10] Chromosomal instability (CIN) is associated with poor prognosis in human cancer. However, in certain animal tumor models elevated CIN negatively impacts upon organism fitness, and is poorly tolerated by cancer cells. To ... Pancreatic Stellate Cells Radioprotect Pancreatic Cancer Cells through beta 1-Integrin Signaling [作者：Mantoni, TS; Lunardi, S; Al-Assar, O; Masamune, A; Brunner, TB,期刊：Cancer research, 页码：3453-3458 , 文章类型： Article，,卷期：2011年71-10] Pancreatic ductal adenocarcinoma (PDAC) is characterized by a strong desmoplastic reaction where the stromal compartment often accounts for more than half of the tumor volume. Pancreatic stellate cells (PSC) are a centra... Role for Stromal Heterogeneity in Prostate Tumorigenesis [作者：Kiskowski, MA; Jackson, RS; Banerjee, J; Li, XH; Kang, MC; Iturregui, JM; Franco, OE; Hayward, SW; Bhowmick, NA,期刊：Cancer research, 页码：3459-3470 , 文章类型： Article，,卷期：2011年71-10] Prostate cancer develops through a stochastic mechanism whereby precancerous lesions on occasion progress to multifocal adenocarcinoma. Analysis of human benign and cancer prostate tissues revealed heterogeneous loss of ... Functional Synergies yet Distinct Modulators Affected by Genetic Alterations in Common Human Cancers [作者：Bessarabova, M; Pustovalova, O; Shi, WW; Serebriyskaya, T; Ishkin, A; Polyak, K; Velculescu, VE; Nikolskaya, T; Nikolsky, Y,期刊：Cancer research, 页码：3471-3481 , 文章类型： Article，,卷期：2011年71-10] An important general concern in cancer research is how diverse genetic alterations and regulatory pathways can produce common signaling outcomes. In this study, we report the construction of cancer models that combine un... Endoglin Regulates Cancer-Stromal Cell Interactions in Prostate Tumors [作者：Romero, D; O'Neill, C; Terzic, A; Contois, L; Young, K; Conley, BA; Bergan, RC; Brooks, PC; Vary, CPH,期刊：Cancer research, 页码：3482-3493 , 文章类型： Article，,卷期：2011年71-10] Endoglin is an accessory receptor for TGF-beta that has been implicated in prostate cancer cell detachment, migration, and invasiveness. However, the pathophysiologic significance of endoglin with respect to prostate tum... Expression of Id-1 Is Regulated by MCAM/MUC18: A Missing Link in Melanoma Progression [作者：Zigler, M; Villares, GJ; Dobroff, AS; Wang, H; Huang, L; Braeuer, RR; Kamiya, T; Melnikova, VO; Song, RD; Friedman, R; Alani, RM; Bar-Eli, M,期刊：Cancer research, 页码：3494-3504 , 文章类型： Article，,卷期：2011年71-10] The acquisition of the metastatic melanoma phenotype is associated with increased expression of the melanoma cell adhesion molecule MCAM/MUC18 (CD146). However, the mechanism by which MUC18 contributes to melanoma metast... Tumor-Evoked Regulatory B Cells Promote Breast Cancer Metastasis by Converting Resting CD4(+) T Cells to T-Regulatory Cells [作者：Olkhanud, PB; Damdinsuren, B; Bodogai, M; Gress, RE; Sen, R; Wejksza, K; Malchinkhuu, E; Wersto, RP; Biragyn, A,期刊：Cancer research, 页码：3505-3515 , 文章类型： Article，,卷期：2011年71-10] Pulmonary metastasis of breast cancer requires recruitment and expansion of T-regulatory cells (Treg) that promote escape from host protective immune cells. However, it remains unclear precisely how tumors recruit Tregs ... Reprogramming CD19-Specific T Cells with IL-21 Signaling Can Improve Adoptive Immunotherapy of B-Lineage Malignancies [作者：Singh, H; Figliola, MJ; Dawson, MJ; Huls, H; Olivares, S; Switzer, K; Mi, TJ; Maiti, S; Kebriaei, P; Lee, DA; Champlin, RE; Cooper, LJN,期刊：Cancer research, 页码：3516-3527 , 文章类型： Article，,卷期：2011年71-10] Improving the therapeutic efficacy of T cells expressing a chimeric antigen receptor (CAR) represents an important goal in efforts to control B-cell malignancies. Recently an intrinsic strategy has been developed to modi... Unraveling Cancer Chemoimmunotherapy Mechanisms by Gene and Protein Expression Profiling of Responses to Cyclophosphamide [作者：Moschella, F; Valentini, M; Arico, E; Macchia, I; Sestili, P; D'Urso, MT; Alessandri, C; Belardelli, F; Proietti, E,期刊：Cancer research, 页码：3528-3539 , 文章类型： Article，,卷期：2011年71-10] Certain chemotherapeutic drugs, such as cyclophosphamide (CTX), can enhance the antitumor efficacy of immunotherapy because of their capacity to modulate innate and adaptive immunity. Indeed, it has been argued that this... Anti-TIM3 Antibody Promotes T Cell IFN-gamma-Mediated Antitumor Immunity and Suppresses Established Tumors [作者：Ngiow, SF; von Scheidt, B; Akiba, H; Yagita, H; Teng, MWL; Smyth, MJ,期刊：Cancer research, 页码：3540-3551 , 文章类型： Article，,卷期：2011年71-10] Strategies to activate and rescue exhausted tumor-specific T cells, including the use of monoclonal antibodies (mAb) that block the negative costimulatory receptors CTLA-4 and PD-1 are proving very effective, but TIM3 ha... miR-125b Is Methylated and Functions as a Tumor Suppressor by Regulating the ETS1 Proto-oncogene in Human Invasive Breast Cancer [作者：Zhang, Y; Yan, LX; Wu, QN; Du, ZM; Chen, J; Liao, DZ; Huang, MY; Hou, JH; Wu, QL; Zeng, MS; Huang, WL; Zeng, YX; Shao, JY,期刊：Cancer research, 页码：3552-3562 , 文章类型： Article，,卷期：2011年71-10] The microRNA miR-125b is dysregulated in various human cancers but its underlying mechanisms of action are poorly understood. Here, we report that miR-125b is downregulated in invasive breast cancers where it predicts po... Human Glioma Growth Is Controlled by MicroRNA-10b [作者：Gabriely, G; Yi, M; Narayan, RS; Niers, JM; Wurdinger, T; Imitola, J; Ligon, KL; Kesari, S; Esau, C; Stephens, RM; Tannous, BA; Krichevsky, AM,期刊：Cancer research, 页码：3563-3572 , 文章类型： Article，,卷期：2011年71-10] MicroRNA (miRNA) expression profiling studies revealed a number of miRNAs dysregulated in the malignant brain tumor glioblastoma. Molecular functions of these miRNAs in gliomagenesis are mainly unknown. We show that inhi... Increased Survival following Tumorigenesis in Ts65Dn Mice That Model Down Syndrome [作者：Yang, AN; Reeves, RH,期刊：Cancer research, 页码：3573-3581 , 文章类型： Article，,卷期：2011年71-10] Epidemiologic results tend to suggest that adults with Down syndrome have a reduced incidence of cancer, but some studies have reached the opposite conclusion. In this study, we offer direct biological evidence in suppor... Evidence That Serum Levels of the Soluble Receptor for Advanced Glycation End Products Are Inversely Associated with Pancreatic Cancer Risk: A Prospective Study [作者：Jiao, L; Weinstein, SJ; Albanes, D; Taylor, PR; Graubard, BI; Virtamo, J; Stolzenberg-Solomon, RZ,期刊：Cancer research, 页码：3582-3589 , 文章类型： Article，,卷期：2011年71-10] Cigarette smoking, obesity, type 2 diabetes, and, to a lesser extent, meat cooked at high temperatures are associated with pancreatic cancer. Cigarette smoke and foods cooked at higher temperatures are major environmenta...