- Phase III Trial of Four Cisplatin-Containing Doublet Combinations in Stage IVB, Recurrent, or Persistent Cervical Carcinoma: A Gynecologic Oncology Group Study
[作者:Monk, BJ; Sill, MW; McMeekin, DS; Cohn, DE; Ramondetta, LM; Boardman, CH; Benda, J; Cella, D,期刊:Journal of clinical oncology, 页码:4649-4655 , 文章类型: Article,,卷期:2009年27-28]
- Purpose Assess toxicity and efficacy of cisplatin (Cis) doublet combinations in advanced and recurrent cervical carcinoma. Patients and Methods Patients were randomly assigned to paclitaxel 135 mg/m(2) over 24 hours plus...
- Placebo-Controlled, Double-Blind, Prospective, Randomized Study on the Effect of Octreotide LAR in the Control of Tumor Growth in Patients With Metastatic Neuroendocrine Midgut Tumors: A Report From the PROMID Study Group
[作者:Rinke, A; Muller, HH; Schade-Brittinger, C; Klose, KJ; Barth, P; Wied, M; Mayer, C; Aminossadati, B; Pape, UF; Blaker, M; Harder, J; Arnold, C; Gress, T; Arnold, R,期刊:Journal of clinical oncology, 页码:4656-4663 , 文章类型: Article,,卷期:2009年27-28]
- Purpose Somatostatin analogs are indicated for symptom control in patients with gastroenteropancreatic neuroendocrine tumors (NETs). The ability of somatostatin analogs to control the growth of well-differentiated metast...
- Health-Related Quality of Life Among Long-Term Rectal Cancer Survivors With an Ostomy: Manifestations by Sex
[作者:Krouse, RS; Herrinton, LJ; Grant, M; Wendel, CS; Green, SB; Mohler, MJ; Baldwin, CM; McMullen, CK; Rawl, SM; Matayoshi, E; Coons, SJ; Hornbrook, MC,期刊:Journal of clinical oncology, 页码:4664-4670 , 文章类型: Article,,卷期:2009年27-28]
- Purpose Intestinal stomas can pose significant challenges for long-term (>= 5 years) rectal cancer (RC) survivors. Specifying common challenges and sociodemographic or clinical differences will further the development of...
- Impact of Micrometastases in the Sentinel Node of Patients With Invasive Breast Cancer
[作者:Hansen, NM; Grube, B; Ye, X; Turner, RR; Brenner, RJ; Sim, MS; Giuliano, AE,期刊:Journal of clinical oncology, 页码:4679-4684 , 文章类型: Proceedings Paper,,卷期:2009年27-28]
- Purpose Lymph node metastases are the most significant prognostic indicator for patients with breast cancer. Sentinel node biopsy (SNB) has led to an increase in the detection of micrometastases in the sentinel node (SN)...
- Concurrent Trastuzumab and HER2/neu-Specific Vaccination in Patients With Metastatic Breast Cancer
[作者:Disis, ML; Wallace, DR; Gooley, TA; Dang, YS; Slota, M; Lu, HL; Coveler, AL; Childs, JS; Higgins, DM; Fintak, PA; dela Rosa, C; Tietje, K; Link, J; Waisman, J; Salazar, LG,期刊:Journal of clinical oncology, 页码:4685-4692 , 文章类型: Article,,卷期:2009年27-28]
- Purpose The primary objectives of this phase I/II study were to evaluate the safety and immunogenicity of combination therapy consisting of concurrent trastuzumab and human epidermal growth factor receptor 2 (HER2)/neu-s...
- Frequent Pathologic Complete Responses in Aggressive Stages II to III Breast Cancers With Every-4-Week Carboplatin and Weekly Paclitaxel With or Without Trastuzumab: A Brown University Oncology Group Study
[作者:Sikov, WM; Dizon, DS; Strenger, R; Legare, RD; Theall, KP; Graves, TA; Gass, JS; Kennedy, TA; Fenton, MA,期刊:Journal of clinical oncology, 页码:4693-4700 , 文章类型: Article,,卷期:2009年27-28]
- Purpose To evaluate the efficacy and safety of neoadjuvant carboplatin and weekly paclitaxel +/- weekly trastuzumab in resectable and locally advanced breast cancer. Patients and Methods Women with stages IIA to IIIB dis...
- Prediction of Local Recurrence, Distant Metastases, and Death After Breast-Conserving Therapy in Early-Stage Invasive Breast Cancer Using a Five-Biomarker Panel
[作者:Millar, EKA; Graham, PH; O'Toole, SA; McNeil, CM; Browne, L; Morey, AL; Eggleton, S; Beretov, J; Theocharous, C; Capp, A; Nasser, E; Kearsley, JH; Delaney, G; Papadatos, G; Fox, C; Sutherland, RL,期刊:Journal of clinical oncology, 页码:4701-4708 , 文章类型: Article,,卷期:2009年27-28]
- Purpose To determine the clinical utility of intrinsic molecular phenotype after breast-conserving therapy (BCT) with lumpectomy and whole-breast irradiation with or without a cavity boost. Patients and Methods Four hund...
- Presence of Intratumoral Neutrophils Is an Independent Prognostic Factor in Localized Renal Cell Carcinoma
[作者:Jensen, HK; Donskov, F; Marcussen, N; Nordsmark, M; Lundbeck, F; von der Maase, H,期刊:Journal of clinical oncology, 页码:4709-4717 , 文章类型: Article,,卷期:2009年27-28]
- Purpose We have previously demonstrated a significant negative impact of intratumoral neutrophils in metastatic renal cell carcinoma. This study assessed intratumoral neutrophils in localized clear cell renal cell carcin...
- Phase I and Biomarker Study of ABT-869, a Multiple Receptor Tyrosine Kinase Inhibitor, in Patients With Refractory Solid Malignancies
[作者:Wong, CI; Koh, TS; Soo, R; Hartono, S; Thng, CH; McKeegan, E; Yong, WP; Chen, CS; Lee, SC; Wong, J; Lim, R; Sukri, N; Lim, SE; Ong, AB; Steinberg, J; Gupta, N; Pradhan, R; Humerickhouse, R; Goh, BC,期刊:Journal of clinical oncology, 页码:4718-4726 , 文章类型: Article,,卷期:2009年27-28]
- Purpose To determine the safety and tolerability of ABT-869 at escalating doses and its effects on biomarkers relevant for antiangiogenic activity in patients with solid malignancies. Patients and Methods Patients with s...
- Early Postoperative Paclitaxel Followed by Concurrent Paclitaxel and Cisplatin With Radiation Therapy for Patients With Resected High-Risk Head and Neck Squamous Cell Carcinoma: Report of the Phase II Trial RTOG 0024
[作者:Rosenthal, DI; Harris, J; Forastiere, AA; Weber, RS; Ridge, JA; Myers, JN; Garden, AS; Kuettel, MR; Sidhu, K; Schultz, CJ; Trotti, A; Ang, KK,期刊:Journal of clinical oncology, 页码:4727-4732 , 文章类型: Article,,卷期:2009年27-28]
- Purpose We sought to improve outcomes for patients with high-risk head and neck squamous cell cancer (HNSCC) after surgical resection by testing the feasibility and safety of early postoperative chemotherapy followed by ...
- Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma
[作者:Friedman, HS; Prados, MD; Wen, PY; Mikkelsen, T; Schiff, D; Abrey, LE; Yung, WKA; Paleologos, N; Nicholas, MK; Jensen, R; Vredenburgh, J; Huang, J; Zheng, MX; Cloughesy, T,期刊:Journal of clinical oncology, 页码:4733-4740 , 文章类型: Article,,卷期:2009年27-28]
- Purpose We evaluated the efficacy of bevacizumab, alone and in combination with irinotecan, in patients with recurrent glioblastoma in a phase II, multicenter, open-label, noncomparative trial. Patients and Methods One h...
- Phase I/II Trial of AEG35156 X-Linked Inhibitor of Apoptosis Protein Antisense Oligonucleotide Combined With Idarubicin and Cytarabine in Patients With Relapsed or Primary Refractory Acute Myeloid Leukemia
[作者:Schimmer, AD; Estey, EH; Borthakur, G; Carter, BZ; Schiller, GJ; Tallman, MS; Altman, JK; Karp, JE; Kassis, J; Hedley, DW; Brandwein, J; Xu, W; Mak, DH; LaCasse, E; Jacob, C; Morris, SJ; Jolivet, J; Andreeff, M,期刊:Journal of clinical oncology, 页码:4741-4746 , 文章类型: Article,,卷期:2009年27-28]
- Purpose X-linked inhibitor of apoptosis protein (XIAP) is an inhibitor of caspases 3 and 9 which are overexpressed in acute myeloid leukemia (AML) and may contribute to chemoresistance. We report on a phase I/II trial of...
- Acute Myeloid Leukemia With Translocation (8;21) or Inversion (16) in Elderly Patients Treated With Conventional Chemotherapy: A Collaborative Study of the French CBF-AML Intergroup
[作者:Prebet, T; Boissel, N; Reutenauer, S; Thomas, X; Delaunay, J; Cahn, JY; Pigneux, A; Quesnel, B; Witz, F; Thepot, S; Ugo, V; Terre, C; Recher, C; Tavernier, E; Hunault, M; Esterni, B; Castaigne, S; Guilhot, F; Dombret, H; Vey, N,期刊:Journal of clinical oncology, 页码:4747-4753 , 文章类型: Article,,卷期:2009年27-28]
- Purpose Acute myeloid leukemia (AML) with translocation (t) (8;21) or inversion (inv) (16) is associated with a favorable prognosis when treated with intensive chemotherapy. In elderly patients, these AML types are rare,...
- High-Dose Imatinib in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia: High Rates of Rapid Cytogenetic and Molecular Responses
[作者:Cortes, JE; Kantarjian, HM; Goldberg, SL; Powell, BL; Giles, FJ; Wetzler, M; Akard, L; Burke, JM; Kerr, R; Saleh, M; Salvado, A; McDougall, K; Albitar, M; Radich, J,期刊:Journal of clinical oncology, 页码:4754-4759 , 文章类型: Article,,卷期:2009年27-28]
- Purpose Long-term clinical outcome data have established imatinib 400 mg/d as standard front-line treatment for newly diagnosed patients with chronic myeloid leukemia (CML). Patients and Methods The Rationale and Insight...
- Lenalidomide Plus Prednisone Results in Durable Clinical, Histopathologic, and Molecular Responses in Patients With Myelofibrosis
[作者:Quintas-Cardama, A; Kantarjian, HM; Manshouri, T; Thomas, D; Cortes, J; Ravandi, F; Garcia-Manero, G; Ferrajoli, A; Bueso-Ramos, C; Verstovsek, S,期刊:Journal of clinical oncology, 页码:4760-4766 , 文章类型: Article,,卷期:2009年27-28]
- Purpose To investigate the safety and efficacy of the combination of lenalidomide and prednisone in patients with myelofibrosis (MF). Patients and Methods Forty patients with MF were treated. Therapy consisted of lenalid...
|