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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共12条记录   Stem Cells and Tissue Regeneration [作者：Di Pietro, R,期刊：Current Pharmaceutical Design, 页码：1677-1678 , 文章类型： Editorial Material，,卷期：2012年18-13] The Architectural Organization of Human Stem Cell Cycle Regulatory Machinery [作者：Stein, GS; Stein, JL; Wijnen, AV; Lian, JB; Montecino, M; Medina, R; Kapinas, K; Ghule, P; Grandy, R; Zaidi, SK; Becker, KA,期刊：Current Pharmaceutical Design, 页码：1679-1685 , 文章类型： Review，,卷期：2012年18-13] Two striking features of human embryonic stem cells that support biological activity are an abbreviated cell cycle and reduced complexity to nuclear organization. The potential implications for rapid proliferation of hum... Chromatin Modification and Senescence [作者：Di Bernardo, G; Cipollaro, M; Galderisi, U,期刊：Current Pharmaceutical Design, 页码：1686-1693 , 文章类型： Review，,卷期：2012年18-13] Cells are the fundamental structure composing our bodies and hence cellular decline (called senescence) contributes to ageing. Endogenous and exogenous stresses may induce cellular senescence. Stressors are mainly macrom... Stem Cell Ageing and Apoptosis [作者：Fulle, S; Centurione, L; Mancinelli, R; Sancilio, S; Manzoli, FA; Di Pietro, R,期刊：Current Pharmaceutical Design, 页码：1694-1717 , 文章类型： Review，,卷期：2012年18-13] Ageing has been defined as the process of deterioration of many body functions over the lifespan of an individual. In spite of the number of different theories about ageing, there is a general consensus in identifying ag... Role of miRNAs in Muscle Stem Cell Biology: Proliferation, Differentiation and Death [作者：Crippa, S; Cassano, M; Sampaolesi, M,期刊：Current Pharmaceutical Design, 页码：1718-1729 , 文章类型： Review，,卷期：2012年18-13] miRNAs are small non-coding RNAs that regulate post-transcriptionally gene expression by degradation or translational repression of specific target mRNAs. In the 90s, lin-4 and let-7 were firstly identified as small regu... The Use of Proteomics for Systematic Analysis of Normal and Transformed Hematopoietic Stem Cells [作者：Cadeco, S; Williamson, AJK; Whetton, AD,期刊：Current Pharmaceutical Design, 页码：1730-1750 , 文章类型： Review，,卷期：2012年18-13] Blood cell production involves the commitment and differentiation of hematopoietic stem cells to committed progenitor cells which undergo a programmed development to form mature cells such as neutrophils, macrophages and... Nuclear PI-PLC beta 1 and Myelodysplastic Syndromes: Genetics and Epigenetics [作者：Follo, MY; Mongiorgi, S; Finelli, C; Piazzi, M; Faenza, I; Ramazzotti, G; Santi, P; McCubrey, JA; Martelli, AM; Cocco, L,期刊：Current Pharmaceutical Design, 页码：1751-1754 , 文章类型： Review，,卷期：2012年18-13] Among cellular second messengers inositides play key roles in signal transduction pathways. Indeed, nuclear phosphoinositide-specific phospholipase C (PI-PLC) beta 1 and Akt are involved in cell cycle progression and apo... Neural Stem Cell Niches in Health and Diseases [作者：Decimo, I; Bifari, F; Krampera, M; Fumagalli, G,期刊：Current Pharmaceutical Design, 页码：1755-1783 , 文章类型： Review，,卷期：2012年18-13] Presence of neural stem cells in adult mammalian brains, including human, has been clearly demonstrated by several studies. The functional significance of adult neurogenesis is slowly emerging as new data indicate the se... Targeting the Cancer Initiating Cell: The Ultimate Target for Cancer Therapy [作者：McCubrey, JA; Steelman, LS; Abrams, SL; Misaghian, N; Chappell, WH; Basecke, J; Nicoletti, F; Libra, M; Ligresti, G; Stivala, F; Maksi-Movic-Ivanic, D; Mijatovic, S; Montalto, G; Cervello, M; Laidler, P; Bonati, A; Evangelisti, C; Cocco, L; Martelli, AM,期刊：Current Pharmaceutical Design, 页码：1784-1795 , 文章类型： Review，,卷期：2012年18-13] An area of therapeutic interest in cancer biology and treatment is targeting the cancer stem cell, more appropriately referred to as the cancer initiating cell (CIC). CICs comprise a subset of hierarchically organized, r... The Combined Use of Mesenchymal Stromal Cells and Scaffolds for Bone Repair [作者：Ciapetti, G; Granchi, D; Baldini, N,期刊：Current Pharmaceutical Design, 页码：1796-1820 , 文章类型： Review，,卷期：2012年18-13] A general principle of stem cell therapy is to exploit the natural ability of the human body to heal through the process of regeneration.Here, we review the current status of cell therapy based on adult mesenchymal stem ... Clinical Applications and Biosafety of Human Adult Mesenchymal Stem Cells [作者：Mariani, E; Facchini, A,期刊：Current Pharmaceutical Design, 页码：1821-1845 , 文章类型： Review，,卷期：2012年18-13] Mesenchymal Stem Cells (MSCs) are a population of adherent cells that can differentiate into mesenchymal lineage populations (cartilage, bone and fat tissue). In addition, they seem to be able to differentiate also into ... Amniotic Fluid Stem Cells: a Promising Therapeutic Resource for Cell-Based Regenerative Therapy [作者：Antonucci, I; Pantalone, A; Tete, S; Salini, V; Borlongan, CV; Hess, D; Stuppia, L,期刊：Current Pharmaceutical Design, 页码：1846-1863 , 文章类型： Review，,卷期：2012年18-13] Stem cells have been proposed as a powerful tool in the treatment of several human diseases, both for their ability to represent a source of new cells to replace those lost due to tissue injuries or degenerative diseases...