- Adenovirus-based virotherapy enabled by cellular YB-1 expression in vitro and in vivo
[作者:Rognoni, E; Widmaier, M; Haczek, C; Mantwill, K; Holzmuller, R; Gansbacher, B; Kolk, A; Schuster, T; Schmid, RM; Saur, D; Kaszubiak, A; Lage, H; Holm, PS,期刊:Cancer gene therapy, 页码:753-763 , 文章类型: Article,,卷期:2009年16-10]
- We have earlier described the oncolytic adenovirus vector dl520 that was rendered cancer-specific by deletion of the transactivation domain CR3 of the adenoviral E1A13S protein; this deletion causes antitumor activity in...
- Adenoviral-mediated, intratumor gene transfer of interleukin 23 induces a therapeutic antitumor response
[作者:Reay, J; Kim, SH; Lockhart, E; Kolls, J; Robbins, PD,期刊:Cancer gene therapy, 页码:776-785 , 文章类型: Article,,卷期:2009年16-10]
- Interleukin 23 (IL-23) is a member of the IL-12 family of heterodimeric cytokines, composed of p19 and p40 subunits, which exhibits immunostimulatory properties similar to IL-12. IL-23 has been shown to possess potent an...
- PNAE mu can significantly reduce Burkitt's lymphoma tumor burden in a SCID mice model: cells dissemination similar to the human disease
[作者:Matis, S; Mariani, MR; Cutrona, G; Cilli, M; Piccardi, F; Daga, A; Damonte, G; Millo, E; Moroni, M; Roncella, S; Fedeli, F; Boffa, LC; Ferrarini, M,期刊:Cancer gene therapy, 页码:786-793 , 文章类型: Article,,卷期:2009年16-10]
- In human Burkitt's Lymphoma (BL) BRG cells, a t(8; 14) translocation, placing c-myc near the E mu enhancer of the H chain locus, causes tumor expansion. Earlier, we showed that a peptide nucleic acid complementary to the...
- CRAdRGDflt-IL24 virotherapy in combination with chemotherapy of experimental glioma
[作者:Kaliberova, LN; Krendelchtchikova, V; Harmon, DK; Stockard, CR; Petersen, AS; Markert, JM; Gillespie, GY; Grizzle, WE; Buchsbaum, DJ; Kaliberov, SA,期刊:Cancer gene therapy, 页码:794-805 , 文章类型: Article,,卷期:2009年16-10]
- Malignant forms of glioma, the most common primary brain tumors, remain poorly responsive to multimodality therapeutic interventions, including chemotherapy. Suppressed apoptosis and extraordinary invasiveness are import...
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