- Expression of HBX, an oncoprotein of hepatitis B virus, blocks reoviral oncolysis of hepatocellular carcinoma cells
[作者:Park, EH; Koh, SS; Srisuttee, R; Cho, IR; Min, HJ; Jhun, BH; Lee, YS; Jang, KL; Kim, CH; Johnston, RN; Chung, YH,期刊:Cancer gene therapy, 页码:453-461 , 文章类型: Article,,卷期:2009年16-5]
Although reovirus has been used in tests as a potential cancer therapeutic agent against a variety of cancer cells, its application to hepatocellular carcinoma cells, in which the hepatitis B virus (HBV) X (HBX) prote...
- An oral TLR7 agonist is a potent adjuvant of DNA vaccination in transgenic mouse tumor models
[作者:Dharmapuri, S; Aurisicchio, L; Neuner, P; Verdirame, M; Ciliberto, G; La Monica, N,期刊:Cancer gene therapy, 页码:462-472 , 文章类型: Article,,卷期:2009年16-5]
- In vivo electroporation of plasmid DNA (DNA-EP) is an efficient and safe method for vaccines resulting in increased DNA uptake, enhanced protein expression and increased immune responses to the target antigen in a variet...
- Nanoparticle delivery of anti-metastatic NM23-H1 gene improves chemotherapy in a mouse tumor model
[作者:Li, Z; Xiang, J; Zhang, W; Fan, S; Wu, M; Li, X; Li, G,期刊:Cancer gene therapy, 页码:423-429 , 文章类型: Article,,卷期:2009年16-5]
- Gene therapy provides a promising approach for cancer treatment. Earlier studies suggested that poly-L-lysine-modified iron oxide nanoparticles (IONP-PLL) might be a promising gene delivery system that can transfect DNA ...
- Retrovirally transduced murine T lymphocytes expressing FasL mediate effective killing of prostate cancer cells
[作者:Symes, JC; Siatskas, C; Fowler, DH; Medin, JA,期刊:Cancer gene therapy, 页码:439-452 , 文章类型: Article,,卷期:2009年16-5]
- Adoptively transferred T cells possess anticancer activities partially mediated by T-cell FasL engagement of Fas tumor targets. However, antigen-induced T-cell activation and clonal expansion, which stimulates FasL activ...
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