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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共9条记录   Intravenous injection of siRNA directed against hypoxia-inducible factors prolongs survival in a Lewis lung carcinoma cancer model [作者：Kamlah, F; Eul, BG; Li, S; Lang, N; Marsh, LM; Seeger, W; Grimminger, F; Rose, F; Hanze, J,期刊：Cancer gene therapy, 页码：195-205 , 文章类型： Article，,卷期：2009年16-3] Different routes for the in vivo administration of synthetic siRNA complexes targeting lung tumors were compared, and siRNA complexes were administered for the inhibition of hypoxia-inducible factor (HIF-1 alpha and HIF-... MicroRNA profile analysis of human prostate cancers [作者：Tong, AW; Fulgham, P; Jay, C; Chen, P; Khalil, I; Liu, S; Senzer, N; Eklund, AC; Han, J; Nemunaitis, J,期刊：Cancer gene therapy, 页码：206-216 , 文章类型： Article，,卷期：2009年16-3] We examined the microRNA (miRNA) expression profile of 40 prostatectomy specimens from stage T2a/b, early relapse and non-relapse cancer patients, to better understand the relationship between miRNA dysregulation and pro... Imaging of cationic multifunctional liposome-mediated delivery of COX-2 siRNA [作者：Mikhaylova, M; Stasinopoulos, I; Kato, Y; Artemov, D; Bhujwalla, ZM,期刊：Cancer gene therapy, 页码：217-226 , 文章类型： Article，,卷期：2009年16-3] Liposomes are a useful means of delivering molecular targeting agents such as small interfering RNA (siRNA) to downregulate specific pathways important in cancer growth and progression. The ability to non-invasively imag... Combined silencing of K-ras and Akt2 oncogenes achieves synergistic effects in inhibiting pancreatic cancer cell growth in vitro and in vivo [作者：Shi, XH; Liang, ZY; Ren, XY; Liu, TH,期刊：Cancer gene therapy, 页码：227-236 , 文章类型： Article，,卷期：2009年16-3] Cancer is a complex disease involving multiple oncogenes with diverse actions. Inhibiting only one oncogene is unlikely to eliminate the malignancy of cancer cells. The goal of this study was to investigate whether syner... The effects of trichostatin A on the oncolytic ability of herpes simplex virus for oral squamous cell carcinoma cells [作者：Katsura, T; Iwai, S; Ota, Y; Shimizu, H; Ikuta, K; Yura, Y,期刊：Cancer gene therapy, 页码：237-245 , 文章类型： Article，,卷期：2009年16-3] Combining the use of a chemotherapeutic agent with oncolytic virotherapy is a useful way to increase the efficiency of the treatment of cancer. The effect of the histone diacetylase (HDAC) inhibitor trichostatin A (TSA) ... Therapy of head and neck squamous cell carcinoma with replicative adenovirus expressing tissue inhibitor of metalloproteinase-2 and chemoradiation [作者：McNally, LR; Rosenthal, EL; Zhang, W; Buchsbaum, DJ,期刊：Cancer gene therapy, 页码：246-255 , 文章类型： Article，,卷期：2009年16-3] Recent studies have demonstrated the efficacy of targeted therapy combined with radiotherapy in head and neck squamous cell carcinoma (HNSCC). We hypothesized that a combination treatment including a replicating adenovir... Oncolytic adenovirus retargeted to Delta-EGFR induces selective antiglioma activity [作者：Piao, Y; Jiang, H; Alemany, R; Krasnykh, V; Marini, FC; Xu, J; Alonso, MM; Conrad, CA; Aldape, KD; Gomez-Manzano, C; Fueyo, J,期刊：Cancer gene therapy, 页码：256-265 , 文章类型： Article，,卷期：2009年16-3] The fact that glioblastomas, which are one of the most devastating cancers, frequently express the Delta-EGFR (epithelial growth factor receptor) also called mutant variant III of EGFR (EGFRvIII) suggests that this cance... Enhanced oncolytic potency of vesicular stomatitis virus through vector-mediated inhibition of NK and NKT cells [作者：Altomonte, J; Wu, L; Meseck, M; Chen, L; Ebert, O; Garcia-Sastre, A; Fallon, J; Mandeli, J; Woo, SLC,期刊：Cancer gene therapy, 页码：266-278 , 文章类型： Article，,卷期：2009年16-3] Recombinant oncolytic viruses represent a promising alternative option for the treatment of malignant cancers. We have reported earlier the safety and efficacy of recombinant vesicular stomatitis virus (VSV) vectors in a... Exploiting the tumor microenvironment in the development of targeted cancer gene therapy [作者：Dougherty, GJ; Dougherty, ST,期刊：Cancer gene therapy, 页码：279-290 , 文章类型： Article，,卷期：2009年16-3] The future success of cancer gene therapy is critically dependent upon the development of safe, practical and effective targeting strategies. In this study, we describe a novel and broadly applicable targeting approach i...