- Compartmentation of NAD(+)-dependent signalling
[作者:Koch-Nolte, F; Fischer, S; Haag, F; Ziegler, M,期刊:FEBS Letters, 页码:1651-1656 , 文章类型: Review,,卷期:2011年585-11]
- NAD(+) plays central roles in energy metabolism as redox carrier. Recent research has identified important signalling functions of NAD(+) that involve its consumption. Although NAD(+) is synthesized mainly in the cytosol...
- How to cope with the quest for new antibiotics
[作者:Fabbretti, A; Gualerzi, CO; Brandi, L,期刊:FEBS Letters, 页码:1673-1681 , 文章类型: Review,,卷期:2011年585-11]
- Since their introduction in therapy, antibiotics have played an essential role in human society, saving millions of lives, allowing safe surgery, organ transplants, cancer therapy. Antibiotics have also helped to elucida...
- Strategies for bypassing the membrane barrier in multidrug resistant Gram-negative bacteria
[作者:Bolla, JM; Alibert-Franco, S; Handzlik, J; Chevalier, J; Mahamoud, A; Boyer, G; Kiec-Kononowicz, K; Pages, JM,期刊:FEBS Letters, 页码:1682-1690 , 文章类型: Review,,卷期:2011年585-11]
- In Gram-negative bacteria, the envelope is a sophisticated barrier protecting the cell against external toxic compounds. Membrane transporters, e. g., porins or efflux pumps, are main filters regulating the internal accu...
- Can polymeric vesicles that confine enzymatic reactions act as simplified organelles?
[作者:Tanner, P; Egli, S; Balasubramanian, V; Onaca, O; Palivan, CG; Meier, W,期刊:FEBS Letters, 页码:1699-1706 , 文章类型: Review,,卷期:2011年585-11]
- In various pathological conditions an advantage may be gained by reinforcing an intrinsic organismal response. This can be achieved, for example, by enzyme replacement therapy, which can amplify specific, intrinsic activ...
- Investigation of cytochromes P450 in myxobacteria: Excavation of cytochromes P450 from the genome of Sorangium cellulosum So ce56
[作者:Khatri, Y; Hannemann, F; Perlova, O; Muller, R; Bernhardt, R,期刊:FEBS Letters, 页码:1506-1513 , 文章类型: Review,,卷期:2011年585-11]
- The exploitation of cytochromes P450 for novel biotechnological application and for the investigation of their physiological function is of great scientific interest in this post genomic era, where an extraordinary biodi...
- NAD(+)-metabolizing ecto-enzymes shape tumor-host interactions: The chronic lymphocytic leukemia model
[作者:Vaisitti, T; Audrito, V; Serra, S; Bologna, C; Brusa, D; Malavasi, F; Deaglio, S,期刊:FEBS Letters, 页码:1514-1520 , 文章类型: Review,,卷期:2011年585-11]
- Nicotinamide adenine dinucleotide (NAD(+)) is an essential co-enzyme that can be released in the extracellular milieu. Here, it may elicit signals through binding purinergic receptors. Alternatively, NAD(+) may be disman...
- Engineering plant resistance by constructing chimeric receptors that recognize damage-associated molecular patterns (DAMPs)
[作者:De Lorenzo, G; Brutus, A; Savatin, DV; Sicilia, F; Cervone, F,期刊:FEBS Letters, 页码:1521-1528 , 文章类型: Review,,卷期:2011年585-11]
- An efficient sensing of danger and a rapid activation of the immune system are crucial for the survival of plants. Conserved pathogen/microbe-associated molecular patterns (PAMPs/MAMPs) and endogenous molecular patterns,...
- Are retinoids potential therapeutic agents in disorders of social cognition including autism?
[作者:Ebstein, RP; Mankuta, D; Yirmiya, N; Malavasi, F,期刊:FEBS Letters, 页码:1529-1536 , 文章类型: Review,,卷期:2011年585-11]
- Increasing evidence suggests that the nonapeptide, oxytocin (OT), helps shape social and affiliative behaviors not only in lower mammals but also in humans. Recently, an essential mediator of brain OT release has been di...
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