- Heat-shock protein 90 inhibitors as antitumor agents: a survey of the literature from 2005 to 2010
[作者:Messaoudi, S; Peyrat, JF; Brion, JD; Alami, M,期刊:Expert Opinion on Therapeutic Patents, 页码:1501-1542 , 文章类型: Review,,卷期:2011年21-10]
- Introduction: Heat-shock protein 90 (Hsp90) is a validated novel anticancer target with unique features. As a molecular chaperone, Hsp90 is implicated in maintaining the conformation, stability, activity and cellular loc...
- New beta-glucan inhibitors as antifungal drugs
[作者:Hector, RF; Bierer, DE,期刊:Expert Opinion on Therapeutic Patents, 页码:1597-1610 , 文章类型: Review,,卷期:2011年21-10]
- Introduction: New classes of synthetic and semi-synthetic beta-glucan inhibitors have recently emerged, providing analogs that, in some cases, have been proven to have a high degree of activity against fungi, offering th...
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