- The invariant chain transports TNF family member CD70 to MHC class II compartments in dendritic cells
[作者:Zwart, W; Peperzak, V; de Vries, E; Keller, AM; van der Horst, G; Veraar, EAM; Geumann, U; Janssen, H; Janssen, L; Naik, SH; Neefjes, J; Borst, J,期刊:Journal of cell science, 页码:3817-3827 , 文章类型: Article,,卷期:2010年123-21]
- CD70 is a TNF-related transmembrane molecule expressed by mature dendritic cells (DCs), which present antigens to T cells via major histocompatibility complex (MHC) molecules. In DCs, CD70 localizes with MHC class II mol...
- Clathrin recruits phosphorylated TACC3 to spindle poles for bipolar spindle assembly and chromosome alignment
[作者:Fu, WX; Tao, W; Zheng, PW; Fu, JY; Bian, ML; Jiang, Q; Clarke, PR; Zhang, CM,期刊:Journal of cell science, 页码:3645-3651 , 文章类型: Article,,卷期:2010年123-21]
- Transforming acidic coiled-coil-containing protein 3 (TACC3) has been implicated in mitotic spindle assembly, although the mechanisms involved are largely unknown. Here we identify that clathrin heavy chain (CHC) binds s...
- Regulation of Hip1r by epsin controls the temporal and spatial coupling of actin filaments to clathrin-coated pits
[作者:Brady, RJ; Damer, CK; Heuser, JE; O'Halloran, TJ,期刊:Journal of cell science, 页码:3652-3661 , 文章类型: Article,,卷期:2010年123-21]
- Recently, it has become clear that the actin cytoskeleton is involved in clathrin-mediated endocytosis. During clathrin-mediated endocytosis, clathrin triskelions and adaptor proteins assemble into lattices, forming clat...
- Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia
[作者:Oser, M; Mader, CC; Gil-Henn, H; Magalhaes, M; Bravo-Cordero, JJ; Koleske, AJ; Condeelis, J,期刊:Journal of cell science, 页码:3662-3673 , 文章类型: Article,,卷期:2010年123-21]
- Invadopodia are matrix-degrading membrane protrusions in invasive carcinoma cells enriched in proteins that regulate actin polymerization. The on-off regulatory switch that initiates actin polymerization in invadopodia r...
- Expression of integrin beta 1 by fibroblasts is required for tissue repair in vivo
[作者:Liu, SX; Xu, SW; Blumbach, K; Eastwood, M; Denton, CP; Eckes, B; Krieg, T; Abraham, DJ; Leask, A,期刊:Journal of cell science, 页码:3674-3682 , 文章类型: Article,,卷期:2010年123-21]
- In tissue repair, fibroblasts migrate into the wound to produce and remodel extracellular matrix (ECM). Integrins are believed to be crucial for tissue repair, but their tissue-specific role in this process is poorly und...
- Dystroglycan controls signaling of multiple hormones through modulation of STAT5 activity
[作者:Leonoudakis, D; Singh, M; Mohajer, R; Mohajer, P; Fata, JE; Campbell, KP; Muschler, JL,期刊:Journal of cell science, 页码:3683-3692 , 文章类型: Article,,卷期:2010年123-21]
- Receptors for basement membrane (BM) proteins, including dystroglycan (DG), coordinate tissue development and function by mechanisms that are only partially defined. To further elucidate these mechanisms, we generated a ...
- The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics
[作者:Harbour, ME; Breusegem, SYA; Antrobus, R; Freeman, C; Reid, E; Seaman, MNJ,期刊:Journal of cell science, 页码:3703-3717 , 文章类型: Article,,卷期:2010年123-21]
- The retromer complex is required for the efficient endosome-to-Golgi retrieval of the CIMPR, sortilin, SORL1, wntless and other physiologically important membrane proteins. Retromer comprises two protein complexes that a...
- BLOS1, a putative BLOC-1 subunit, interacts with SNX1 and modulates root growth in Arabidopsis
[作者:Cui, YY; Li, XG; Chen, QG; He, X; Yang, Q; Zhang, AL; Yu, X; Chen, H; Liu, NY; Xie, Q; Yang, WC; Zuo, JR; Palme, K; Li, W,期刊:Journal of cell science, 页码:3727-3733 , 文章类型: Article,,卷期:2010年123-21]
- Internalization and sorting of macromolecules are inherent properties of all eukaryotic cells that are achieved by vesicle trafficking. However, this process is relatively less understood in plants. An eight-subunit prot...
- Polypurine-repeat-containing RNAs: a novel class of long non-coding RNA in mammalian cells
[作者:Zheng, RP; Shen, Z; Tripathi, V; Xuan, ZY; Freier, SM; Bennett, CF; Prasanth, SG; Prasanth, KV,期刊:Journal of cell science, 页码:3734-3744 , 文章类型: Article,,卷期:2010年123-21]
- In higher eukaryotic cells, long non-protein-coding RNAs (lncRNAs) have been implicated in a wide array of cellular functions. Cell-or tissue-specific expression of lncRNA genes encoded in the mammalian genome is thought...
- Costars, a Dictyostelium protein similar to the C-terminal domain of STARS, regulates the actin cytoskeleton and motility
[作者:Pang, TL; Chen, FC; Weng, YL; Liao, HC; Yi, YH; Ho, CL; Lin, CH; Chen, MY,期刊:Journal of cell science, 页码:3745-3755 , 文章类型: Article,,卷期:2010年123-21]
- Through analysis of a chemotaxis mutant obtained from a genetic screen in Dictyostelium discoideum, we have identified a new gene involved in regulating cell migration and have named it costars (cosA). The 82 amino acid ...
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