- CD74: an emerging opportunity as a therapeutic target in cancer and autoimmune disease
[作者:Borghese, F; Clanchy, FIL,期刊:Expert Opinion on Therapeutic Targets, 页码:237-251 , 文章类型: Review,,卷期:2011年15-3]
- Introduction: CD74, also known as the invariant chain, participates in several key processes of the immune system, including antigen presentation, B-cell differentiation and inflammatory signaling. Despite being describe...
- Targeting protein neddylation: a novel therapeutic strategy for the treatment of cancer
[作者:Wang, M; Medeiros, BC; Erba, HP; DeAngelo, DJ; Giles, FJ; Swords, RT,期刊:Expert Opinion on Therapeutic Targets, 页码:253-264 , 文章类型: Review,,卷期:2011年15-3]
- Introduction: The NEDD8 (neural precursor cell-expressed developmentally downregulated 8) conjugation pathway regulates the post-translational modification of oncogenic proteins. This pathway has important potential for ...
- Update on the endocannabinoid system as an anticancer target
[作者:Malfitano, AM; Ciaglia, E; Gangemi, G; Gazzerro, P; Laezza, C; Bifulco, M,期刊:Expert Opinion on Therapeutic Targets, 页码:297-308 , 文章类型: Review,,卷期:2011年15-3]
- Introduction: Recent studies have shown that the endocannabinoid system (ECS) could offer an attractive antitumor target. Numerous findings suggest the involvement of this system ( constituted mainly by cannabinoid recep...
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