- IL-33: a promising therapeutic target for rheumatoid arthritis?
[作者:Yuan, FL; Li, X; Lu, WG; Li, CW; Xu, RS; Dong, JA,期刊:Expert Opinion on Therapeutic Targets, 页码:529-534 , 文章类型: Editorial Material,,卷期:2011年15-5]
- Cytokine-mediated immunity plays a crucial role in the pathogenesis of various autoimmune diseases, including rheumatoid arthritis (RA). Recently, the IL-1-family-related cytokine, IL-33, was detected at high levels in e...
- Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders
[作者:Hayashi, T; Tsai, SY; Mori, T; Fujimoto, M; Su, TP,期刊:Expert Opinion on Therapeutic Targets, 页码:557-577 , 文章类型: Review,,卷期:2011年15-5]
- Areas covered: Recent evidence that has shed light on sigma-1 receptor ligands, which may serve as a new class of antidepressants or neuroprotective agents. Sigma-1 receptors are novel ligand-operated molecular chaperone...
- Mitochondrion: an emerging platform critical for host antiviral signaling
[作者:Wang, C; Liu, XY; Wei, B,期刊:Expert Opinion on Therapeutic Targets, 页码:647-665 , 文章类型: Review,,卷期:2011年15-5]
- Areas covered: This review covers the literature of the past 6 years and summarizes the components, regulation and mechanisms of RLR signaling, highlighting the function and regulation of mitochondrial proteins, such as ...
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