- Antibiotic and synergistic effect of Leu-Lys rich peptide against antibiotic resistant microorganisms isolated from patients with cholelithiasis
[作者:Jeong, N; Kim, JY; Park, SC; Lee, JK; Gopal, R; Yoo, S; Son, BK; Hahm, JS; Park, Y; Hahm, KS,期刊:Biochemical and Biophysical Research Communications, 页码:581-586 , 文章类型: Article,,卷期:2010年399-4]
- Pseudomonas aeruginosa has eventually developed resistance against flomoxef sodium, isepamicin and cefpiramide. Therefore, in this study, the antibacterial activity and synergistic effects of the amphipathic-derived P5-1...
- Reduction of amyloid beta-peptide accumulation in Tg2576 transgenic mice by oral vaccination
[作者:Ishii-Katsuno, R; Nakajima, A; Katsuno, T; Nojima, J; Futai, E; Sasagawa, N; Yoshida, T; Watanabe, Y; Ishiura, S,期刊:Biochemical and Biophysical Research Communications, 页码:593-599 , 文章类型: Article,,卷期:2010年399-4]
- Alzheimer's disease (AD) is pathologically characterized by the presence of extracellular senile plaques and intracellular neurofibrillary tangles. Amyloid beta-peptide (A beta) is the main component of senile plaques, a...
- Outer membrane vesicles of Vibrio vulnificus deliver cytolysin-hemolysin Vvha into epithelial cells to induce cytotoxicity
[作者:Kim, YR; Kim, BU; Kim, SY; Kim, CM; Na, HS; Koh, JT; Choy, HE; Rhee, JH; Lee, SE,期刊:Biochemical and Biophysical Research Communications, 页码:607-612 , 文章类型: Article,,卷期:2010年399-4]
- The Gram-negative bacterium Vibrio vulnificus produces cytotoxins that induce the acute death of host cells. However, the secretory mechanisms of such cytotoxins have not been extensively studied. Previously, we reported...
- New molecular mechanisms of the unexpectedly complex role of VEGF in ulcerative colitis
[作者:Tolstanova, G; Khomenko, T; Deng, XM; Szabo, S; Sandor, Z,期刊:Biochemical and Biophysical Research Communications, 页码:613-616 , 文章类型: Article,,卷期:2010年399-4]
- The effects of VEGF on endothelial cells are mediated by different intracellular signaling cascades (e.g., Erk1/2, Akt, Src). VEGF plays a recently recognized role in ulcerative colitis (UC) pathogenesis, mostly by incre...
- Selective destruction of mouse islet beta cells by human T lymphocytes in a newly-established humanized type 1 diabetic model
[作者:Zhao, Y; Guo, CS; Hwang, D; Lin, B; Dingeldein, M; Mihailescu, D; Sam, S; Sidhwani, S; Zhang, Y; Jain, S; Skidgel, RA; Prabhakar, BS; Mazzone, T; Holterman, MJ,期刊:Biochemical and Biophysical Research Communications, 页码:629-636 , 文章类型: Article,,卷期:2010年399-4]
- Type 1 diabetes (T1D) is caused by a T cell-mediated autoimmune response that leads to the loss of insulin-producing p cells. The optimal preclinical testing of promising therapies would be aided by a humanized immune-me...
- Indoxyl sulfate, a uremic toxin, promotes cell senescence in aorta of hypertensive rats
[作者:Adijiang, A; Higuchi, Y; Nishijima, F; Shimizu, H; Niwa, T,期刊:Biochemical and Biophysical Research Communications, 页码:637-641 , 文章类型: Article,,卷期:2010年399-4]
- We demonstrated that administration of indoxyl sulfate, a uremic toxin, promotes aortic calcification in hypertensive rats. This study aimed to clarify if indoxyl sulfate could contribute to cell senescence in the aorta ...
- LPS-induced NF-kappa B expression in THP-1Blue cells correlates with neopterin production and activity of indoleamine 2,3-dioxygenase
[作者:Schroecksnadel, S; Jenny, M; Kurz, K; Klein, A; Ledochowski, M; Uberall, F; Fuchs, D,期刊:Biochemical and Biophysical Research Communications, 页码:642-646 , 文章类型: Article,,卷期:2010年399-4]
- Neopterin production is induced in human monocyte-derived macrophages and dendritic cells upon stimulation with Th1-type cytokine interferon-gamma (IFN-gamma). In parallel, IFN-gamma induces the tryptophan-(trp)-degradin...
- Mitochondrial ND6 T14502C variant may modulate the phenotypic expression of LHON-associated G11778A mutation in four Chinese families
[作者:Zhang, JJ; Zhou, XT; Zhou, JA; Li, CW; Zhao, FX; Wang, Y; Meng, YZ; Wang, JY; Yuan, MX; Cai, WS; Tong, Y; Sun, YH; Yang, L; Qu, J; Guan, MX,期刊:Biochemical and Biophysical Research Communications, 页码:647-653 , 文章类型: Article,,卷期:2010年399-4]
- We report here the clinical, genetic, and molecular evaluations of four Han Chinese families with Leber's hereditary optic neuropathy. Thirty-one (20 males/11 females) of 83 matrilineal relatives in these families exhibi...
- Flavohemoglobin and nitric oxide detoxification in the human protozoan parasite Giardia intestinalis
[作者:Mastronicola, D; Testa, F; Forte, E; Bordi, E; Pucillo, LP; Sarti, P; Giuffre, A,期刊:Biochemical and Biophysical Research Communications, 页码:654-658 , 文章类型: Article,,卷期:2010年399-4]
- Flavohemoglobins (flavoHbs), commonly found in bacteria and fungi, afford protection from nitrosative stress by degrading nitric oxide (NO) to nitrate. Giardia intestinalis, a microaerophilic parasite causing one of the ...
- Phosphorylation of the protein kinase A catalytic subunit is induced by cyclic AMP deficiency and physiological stresses in the fission yeast, Schizosaccharomyces pombe
[作者:McInnis, B; Mitchell, J; Marcus, S,期刊:Biochemical and Biophysical Research Communications, 页码:665-669 , 文章类型: Article,,卷期:2010年399-4]
- In the fission yeast, Schizosaccharomyces pombe, cyclic AMP (cAMP)-dependent protein kinase (PKA) is not essential for viability under normal culturing conditions, making this organism attractive for investigating mechan...
- Testosterone affects hormone-sensitive lipase (HSL) activity and lipid metabolism in the left ventricle
[作者:Langfort, J; Jagsz, S; Dobrzyn, P; Brzezinska, Z; Klapcinska, B; Galbo, H; Gorski, J,期刊:Biochemical and Biophysical Research Communications, 页码:670-676 , 文章类型: Article,,卷期:2010年399-4]
- Fatty acids, which are the major cardiac fuel, are derived from lipid droplets stored in cardiomyocytes, among other sources. The heart expresses hormone-sensitive lipase (HSL), which regulates triglycerides (TG) breakdo...
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