- Treating inflammation with the Janus Kinase inhibitor CP-690,550
[作者:Vijayakrishnan, L; Venkataramanan, R; Gulati, P,期刊:Trends in Pharmacological Sciences, 页码:25-34 , 文章类型: Review,,卷期:2011年32-1]
- Commonly used immunosuppressants possess several significant dose-limiting toxicities, prompting the search for agents whose mechanisms of action are limited to immune cells. Inhibition of Janus Kinase 3 (JAK3), a hemato...
- Genomic and proteomic strategies to identify novel targets potentially involved in learning and memory
[作者:Benoit, CE; Rowe, WB; Menard, C; Sarret, P; Quirion, R,期刊:Trends in Pharmacological Sciences, 页码:43-52 , 文章类型: Review,,卷期:2011年32-1]
- The hippocampus is a crucial player across several learning and memory domains, and is highly vulnerable to alterations during aging. Several products of neurotransmitter genes and neuromodulator genes (which play import...
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