- Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences
[作者：Hartig, JV; Esslinger, S; Bottcher, R; Saito, K; Forstemann, K,期刊：EMBO journal, 页码：2932-2944 , 文章类型： Article，,卷期：2009年28-19]
- Colonization of genomes by a new selfish genetic element is detrimental to the host species and must lead to an efficient, repressive response. In vertebrates as well as in Drosophila, piRNAs repress transposons in the g...
- Systematic and single cell analysis of Xenopus Piwi-interacting RNAs and Xiwi
[作者：Lau, NC; Ohsumi, T; Borowsky, M; Kingston, RE; Blower, MD,期刊：EMBO journal, 页码：2945-2958 , 文章类型： Article，,卷期：2009年28-19]
- Piwi proteins and Piwi-interacting RNAs (piRNAs) are essential for germ cell development, but analysis of the molecular mechanisms of these ribonucleoproteins remains challenging in most animal germ cells. To address thi...
- Cotranslational assembly of the yeast SET1C histone methyltransferase complex
[作者：Halbach, A; Zhang, HD; Wengi, A; Jablonska, Z; Gruber, IML; Halbeisen, RE; Dehe, PM; Kemmeren, P; Holstege, F; Geli, V; Gerber, AP; Dichtl, B,期刊：EMBO journal, 页码：2959-2970 , 文章类型： Article，,卷期：2009年28-19]
- While probing the role of RNA for the function of SET1C/COMPASS histone methyltransferase, we identified SET1RC (SET1 m (R) under bar NA-associated complex), a complex that contains SET1 mRNA and Set1, Swd1, Spp1 and Shg...
- Molecular insights into the recruitment of TFIIH to sites of DNA damage
[作者：Oksenych, V; de Jesus, BB; Zhovmer, A; Egly, JM; Coin, F,期刊：EMBO journal, 页码：2971-2980 , 文章类型： Article，,卷期：2009年28-19]
- XPB and XPD subunits of TFIIH are central genome caretakers involved in nucleotide excision repair (NER), although their respective role within this DNA repair pathway remains difficult to delineate. To obtain insight in...
- Mechanism of polymerase collision release from sliding clamps on the lagging strand
[作者：Georgescu, RE; Kurth, I; Yao, NY; Stewart, J; Yurieva, O; O'Donnell, M,期刊：EMBO journal, 页码：2981-2991 , 文章类型： Article，,卷期：2009年28-19]
- Replicative polymerases are tethered to DNA by sliding clamps for processive DNA synthesis. Despite attachment to a sliding clamp, the polymerase on the lagging strand must cycle on and off DNA for each Okazaki fragment....
- A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome
[作者：Gambus, A; van Deursen, F; Polychronopoulos, D; Foltman, M; Jones, RC; Edmondson, RD; Calzada, A; Labib, K,期刊：EMBO journal, 页码：2992-3004 , 文章类型： Article，,卷期：2009年28-19]
- The eukaryotic replisome is a crucial determinant of genome stability, but its structure is still poorly understood. We found previously that many regulatory proteins assemble around the MCM2-7 helicase at yeast replicat...
- MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication
[作者：Xu, XH; Rochette, PJ; Feyissa, EA; Su, TV; Liu, YL,期刊：EMBO journal, 页码：3005-3014 , 文章类型： Article，,卷期：2009年28-19]
- Mutations in RECQ4, a member of the RecQ family of DNA helicases, have been linked to the progeroid disease Rothmund-Thomson Syndrome. Attempts to understand the complex phenotypes observed in recq4-deficient cells sugge...
- Neurogranin enhances synaptic strength through its interaction with calmodulin
[作者：Zhong, L; Cherry, T; Bies, CE; Florence, MA; Gerges, NZ,期刊：EMBO journal, 页码：3027-3039 , 文章类型： Article，,卷期：2009年28-19]
- Learning-correlated plasticity at CA1 hippocampal excitatory synapses is dependent on neuronal activity and NMDA receptor (NMDAR) activation. However, the molecular mechanisms that transduce plasticity stimuli to postsyn...
- Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha 7 nicotinic acetylcholine receptor
[作者：Hibbs, RE; Sulzenbacher, G; Shi, JX; Talley, TT; Conrod, S; Kem, WR; Taylor, P; Marchot, P; Bourne, Y,期刊：EMBO journal, 页码：3040-3051 , 文章类型： Article，,卷期：2009年28-19]
- The pentameric acetylcholine-binding protein ( AChBP) is a soluble surrogate of the ligand binding domain of nicotinic acetylcholine receptors. Agonists bind within a nest of aromatic side chains contributed by loops C a...
- Functional architecture of higher plant photosystem II supercomplexes
[作者：Caffarri, S; Kouril, R; Kereiche, S; Boekema, EJ; Croce, R,期刊：EMBO journal, 页码：3052-3063 , 文章类型： Article，,卷期：2009年28-19]
- Photosystem II ( PSII) is a large multiprotein complex, which catalyses water splitting and plastoquinone reduction necessary to transform sunlight into chemical energy. Detailed functional and structural studies of the ...
- The making of a chloroplast
[作者：Waters, MT; Langdale, JA,期刊：EMBO journal, 页码：2861-2873 , 文章类型： Review，,卷期：2009年28-19]
- Since its endosymbiotic beginning, the chloroplast has become fully integrated into the biology of the host eukaryotic cell. The exchange of genetic information from the chloroplast to the nucleus has resulted in conside...
- NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain
[作者：Laplantine, E; Fontan, E; Chiaravalli, J; Lopez, T; Lakisic, G; Veron, M; Agou, F; Israel, A,期刊：EMBO journal, 页码：2885-2895 , 文章类型： Article，,卷期：2009年28-19]
- An important property of NEMO, the core element of the IKK complex involved in NF-kappa B activation, resides in its ability to specifically recognize poly-ubiquitin chains. A small domain called NOA/UBAN has been sugges...
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