- Cilengitide: an integrin-targeting arginine-glycine-aspartic acid peptide with promising activity for glioblastoma multiforme
[作者:Reardon, DA; Nabors, LB; Stupp, R; Mikkelsen, T,期刊:Expert opinion on investigational drugs, 页码:1225-1235 , 文章类型: Article,,卷期:2008年17-8]
Background: Glioblastoma multiforme (GBM), a highly invasive and vascular cancer, responds poorly to conventional cytotoxic therapy. Integrins, widely expressed in GBM and tumor vasculature, mediate cell survival, mig...
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