- Contact activation of kallikrein-kinin system by superparamagnetic iron oxide nanoparticles in vitro and in vivo
[作者:Simberg, D; Zhang, WM; Merkulov, S; McCrae, K; Park, JH; Sailor, MJ; Ruoslahti, E,期刊:Journal of controlled release, 页码:301-305 , 文章类型: Proceedings Paper,,卷期:2009年140-3]
- Previously we reported that plasma kallikrein and high molecular weight kininogen attach to the surface of dextran-coated superparamagnetic iron oxide nanoparticles (SPION) through the incompletely covered iron oxide cor...
- Enhanced magnetic resonance imaging of experimental pancreatic tumor in vivo by block copolymer-coated magnetite nanoparticles with TGF-beta inhibitor
[作者:Kumagai, M; Kano, MR; Morishita, Y; Ota, M; Imai, Y; Nishiyama, N; Sekino, M; Ueno, S; Miyazono, K; Kataoka, K,期刊:Journal of controlled release, 页码:306-311 , 文章类型: Proceedings Paper,,卷期:2009年140-3]
- Early detection of solid tumors, particularly pancreatic cancer, is of substantial importance in clinics. Enhanced magnetic resonance imaging (MRI) with iron oxide nanoparticles is an available way to detect the cancer. ...
- Raspberry-like assembly of cross-linked nanogels for protein delivery
[作者:Hasegawa, U; Sawada, S; Shimizu, T; Kishida, T; Otsuji, E; Mazda, O; Akiyoshi, K,期刊:Journal of controlled release, 页码:312-317 , 文章类型: Proceedings Paper,,卷期:2009年140-3]
- Raspberry-like assembly of nanogels (A-CHPNG) with a high potential as a carrier for protein delivery was prepared. Cross-linking of acrylate group-modified cholesterol-bearing pullulan nanogel (CHPANG) with thiol group-...
- The 14th International Symposium on Recent Advances in Drug Delivery Systems, February 15-18, 2009, Salt Lake City, UT, USA Preface
[作者:Park, K; Bae, YH; Grainger, DW,期刊:Journal of controlled release, 页码:183-184 , 文章类型: Editorial Material,,卷期:2009年140-3]
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- Self-oscillating gel as novel biomimetic materials
[作者:Yoshida, R; Sakai, T; Hara, Y; Maeda, S; Hashimoto, S; Suzuki, D; Murase, Y,期刊:Journal of controlled release, 页码:186-193 , 文章类型: Proceedings Paper,,卷期:2009年140-3]
- Stimuli-responsive polymers and their application to biomaterials have been widely studied. On the other hand, as a novel biomimetic polymer, we have been studying the polymer with an autonomous self-oscillating function...
- Hydrotropic oligomer-conjugated glycol chitosan as a carrier of paclitaxel: Synthesis, characterization, and in vivo biodistribution
[作者:Saravanakumar, G; Min, KH; Min, DS; Kim, AY; Lee, CM; Cho, YW; Lee, SC; Kim, K; Jeong, SY; Park, K; Park, JH; Kwon, IC,期刊:Journal of controlled release, 页码:210-217 , 文章类型: Proceedings Paper,,卷期:2009年140-3]
- Development of successful formulations for poorly water-soluble drugs remains a longstanding critical and challenging issue in cancer therapy. As a potential drug carrier of paclitaxel, hydrotropic oligomer-glycol chitos...
- Accelerated release of a sparingly soluble drug from an injectable hyaluronan-methylcellulose hydrogel
[作者:Wang, YF; Lapitsky, Y; Kang, CE; Shoichet, MS,期刊:Journal of controlled release, 页码:218-223 , 文章类型: Proceedings Paper,,卷期:2009年140-3]
- An injectable hydrogel, comprised of hyaluronan and methylcellulose (HAMC), shows promise for localized, sustained delivery of growth factors for treatment of spinal cord injury (SCI). To better understand its potential ...
- Photopolymerized thermosensitive hydrogels for tailorable diffusion-controlled protein delivery
[作者:Censi, R; Vermonden, T; van Steenbergen, MJ; Deschout, H; Braeckmans, K; De Smedt, SC; van Nostrum, CF; di Martino, P; Hennink, WE,期刊:Journal of controlled release, 页码:230-236 , 文章类型: Proceedings Paper,,卷期:2009年140-3]
- In this paper the possibility to tailor degradation and protein release behavior of photo polymerized thermosensitive hydrogels is studied. The hydrogels consist of ABA triblock copolymer, in which the thermosensitive A-...
- Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD
[作者:Watkins, CL; Brennan, P; Fegan, C; Takayama, K; Nakase, I; Futaki, S; Jones, AT,期刊:Journal of controlled release, 页码:237-244 , 文章类型: Proceedings Paper,,卷期:2009年140-3]
- The capacity of cell penetrating peptides (CPPs) to breach biological membranes offers hope for their utilisation as vectors for the delivery of small molecule drugs and macromolecular therapeutics. Using three different...
- Controlling subcellular localization to alter function: Sending oncogenic Bcr-Abl to the nucleus causes apoptosis
[作者:Dixon, AS; Kakar, M; Schneider, KMH; Constance, JE; Paullin, BC; Lim, CS,期刊:Journal of controlled release, 页码:245-249 , 文章类型: ,,卷期:2009年140-3]
Altering the subcellular localization of signal transducing proteins is a novel approach for therapeutic intervention. Mislocalization of tumor suppressors, oncogenes, or factors involved in apoptosis results in aberr...
- Release, biological potency, and biochemical integrity of recombinant human platelet-derived growth factor-BB (rhPDGF-BB) combined with Augment (TM) Bone Graft or GEM 21S beta-tricalcium phosphate (beta-TCP)
[作者:Young, CS; Ladd, PA; Browning, CF; Thompson, A; Bonomo, J; Shockley, K; Hart, CE,期刊:Journal of controlled release, 页码:250-255 , 文章类型: Proceedings Paper,,卷期:2009年140-3]
- Over 10 million surgical procedures are performed annually in the United States to treat musculoskeletal injuries, and a significant portion of these involve orthopedic bone grafting. The goals of the study were to evalu...
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