- Effects of phosphorylation and neuronal activity on the control of synapse formation by synapsin I
[作者:Perlini, LE; Botti, F; Fornasiero, EF; Giannandrea, M; Bonanomi, D; Amendola, M; Naldini, L; Benfenati, F; Valtorta, F,期刊:Journal of cell science, 页码:3643-3653 , 文章类型: Article,,卷期:2011年124-21]
- Synapsins are synaptic vesicle (SV)-associated proteins that regulate synaptic transmission and neuronal differentiation. At early stages, Syn I and II phosphorylation at Ser9 by cAMP-dependent protein kinase (PKA) and C...
- Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle
[作者:Uezumi, A; Ito, T; Morikawa, D; Shimizu, N; Yoneda, T; Segawa, M; Yamaguchi, M; Ogawa, R; Matev, MM; Miyagoe-Suzuki, Y; Takeda, S; Tsujikawa, K; Tsuchida, K; Yamamoto, H; Fukada, S,期刊:Journal of cell science, 页码:3654-3664 , 文章类型: Article,,卷期:2011年124-21]
- Accumulation of adipocytes and collagen type-I-producing cells (fibrosis) is observed in muscular dystrophies. The origin of these cells had been largely unknown, but recently we identified mesenchymal progenitors positi...
- FAT10 mediates the effect of TNF-alpha in inducing chromosomal instability
[作者:Ren, JW; Wang, Y; Gao, Y; Mehta, SBK; Lee, CGL,期刊:Journal of cell science, 页码:3665-3675 , 文章类型: Article,,卷期:2011年124-21]
- Tumor necrosis factor-alpha (TNF-alpha) plays important roles in chronic inflammation-associated tumorigenesis but the mechanisms involved remain poorly understood. Previously, we reported that high levels of FAT10 led t...
- Different roles for Aurora B in condensin targeting during mitosis and meiosis
[作者:Collette, KS; Petty, EL; Golenberg, N; Bembenek, JN; Csankovszki, G,期刊:Journal of cell science, 页码:3684-3694 , 文章类型: Article,,卷期:2011年124-21]
- Condensin complexes are essential for mitotic and meiotic chromosome segregation. Caenorhabditis elegans, like other metazoans, has two distinct mitotic and meiotic condensin complexes (I and II), which occupy distinct c...
- Peroxiredoxin-controlled G-CSF signalling at the endoplasmic reticulum-early endosome interface
[作者:Palande, K; Roovers, O; Gits, J; Verwijmeren, C; Iuchi, Y; Fujii, J; Neel, BG; Karisch, R; Tavernier, J; Touw, IP,期刊:Journal of cell science, 页码:3695-3705 , 文章类型: Article,,卷期:2011年124-21]
- Reactive oxygen species (ROS) regulate growth factor receptor signalling at least in part by inhibiting oxidation-sensitive phosphatases. An emerging concept is that ROS act locally to affect signal transduction in diffe...
- Nucleostemin inhibits TRF1 dimerization and shortens its dynamic association with the telomere
[作者:Meng, LJ; Hsu, JK; Zhu, QB; Lin, T; Tsai, RYL,期刊:Journal of cell science, 页码:3706-3714 , 文章类型: Article,,卷期:2011年124-21]
- TRF1 is a key component of the telomere-capping complex and binds double-strand telomeric DNA as homodimers. So far, it is not clear whether TRF1 dimerization coincides with its telomere binding or is actively controlled...
- Ligand of Numb proteins LNX1p80 and LNX2 interact with the human glycoprotein CD8 alpha and promote its ubiquitylation and endocytosis
[作者:D'Agostino, M; Tornillo, G; Caporaso, MG; Barone, MV; Ghigo, E; Bonatti, S; Mottola, G,期刊:Journal of cell science, 页码:3545-3556 , 文章类型: Article,,卷期:2011年124-21]
- E3 ubiquitin ligases give specificity to the ubiquitylation process by selectively binding substrates. Recently, their function has emerged as a crucial modulator of T-cell tolerance and immunity. However, substrates, pa...
- Protein aggregation of SERCA2 mutants associated with Darier disease elicits ER stress and apoptosis in keratinocytes
[作者:Wang, Y; Bruce, AT; Tu, CX; Ma, KL; Zeng, L; Zheng, P; Liu, Y; Liu, Y,期刊:Journal of cell science, 页码:3568-3580 , 文章类型: Article,,卷期:2011年124-21]
- Mutations in sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) underlie Darier disease (DD), a dominantly inherited skin disorder characterized by loss of keratinocyte adhesion (acantholysis) and abnormal kera...
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