- Mps1 at kinetochores is essential for female mouse meiosis I
[作者：Hached, K; Xie, SZ; Buffin, E; Cladiere, D; Rachez, C; Sacras, M; Sorger, PK; Wassmann, K,期刊：Journal of cell science, 页码：2261-2271 , 文章类型： Article，,卷期：2011年124-11]
- In female meiosis, chromosome missegregations lead to the generation of aneuploid oocytes and can cause the development of trisomies or infertility. Because mammalian female meiosis I is error prone, the full functionali...
- Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila
[作者：Fernandez, BG; Gaspar, P; Bras-Pereira, C; Jezowska, B; Rebelo, SR; Janody, F,期刊：Journal of cell science, 页码：2337-2346 , 文章类型： Article，,卷期：2011年124-11]
- The conserved Hippo tumor suppressor pathway is a key kinase cascade that controls tissue growth by regulating the nuclear import and activity of the transcription co-activator Yorkie. Here, we report that the actin-Capp...
- Ezrin is required for efficient Rap1-induced cell spreading
[作者：Ross, SH; Post, A; Raaijmakers, JH; Verlaan, I; Gloerich, M; Bos, JL,期刊：Journal of cell science, 页码：1808-1818 , 文章类型： Article，,卷期：2011年124-11]
- The Rap family of small GTPases regulate the adhesion of cells to extracellular matrices. Several Rap-binding proteins have been shown to function as effectors that mediate Rap-induced adhesion. However, little is known ...
- VEGF-mediated PI3K class IA and PKC signaling in cardiomyogenesis and vasculogenesis of mouse embryonic stem cells
[作者：Bekhite, MM; Finkensieper, A; Binas, S; Muller, J; Wetzker, R; Figulla, HR; Sauer, H; Wartenberg, M,期刊：Journal of cell science, 页码：1819-1830 , 文章类型： Article，,卷期：2011年124-11]
- VEGF-, phosphoinositide 3-kinase (PI3K)- and protein kinase C (PKC)-regulated signaling in cardiac and vascular differentiation was investigated in mouse ES cells and in ES cell-derived Flk-1(+) cardiovascular progenitor...
- Regulation of Notch1 signaling by the APP intracellular domain facilitates degradation of the Notch1 intracellular domain and RBP-Jk
[作者：Kim, MY; Mo, JS; Ann, EJ; Yoon, JH; Jung, J; Choi, YH; Kim, SM; Kim, HY; Ahn, JS; Kim, H; Kim, K; Hoe, HS; Park, HS,期刊：Journal of cell science, 页码：1831-1843 , 文章类型： Article，,卷期：2011年124-11]
- The Notch1 receptor is a crucial controller of cell fate decisions, and is also a key regulator of cell growth and differentiation in a variety of contexts. In this study, we have demonstrated that the APP intracellular ...
- In vivo functional analysis reveals specific roles for the integrin-binding sites of talin
[作者：Ellis, SJ; Pines, M; Fairchild, MJ; Tanentzapf, G,期刊：Journal of cell science, 页码：1844-1856 , 文章类型： Article，,卷期：2011年124-11]
- Adhesion receptors play diverse roles during animal development and require precise spatiotemporal regulation, which is achieved through the activity of their binding partners. Integrins, adhesion receptors that mediate ...
- Interplay between FGF2 and BMP controls the self-renewal, dormancy and differentiation of rat neural stem cells
[作者：Sun, YR; Hu, J; Zhou, LF; Pollard, SM; Smith, A,期刊：Journal of cell science, 页码：1867-1877 , 文章类型： Article，,卷期：2011年124-11]
- Mouse and human central nervous system progenitor cells can be propagated extensively ex vivo as stem cell lines. For the rat, however, in vitro expansion has proven to be problematic owing to proliferation arrest and di...
- Histone H4K20me3 and HP1 alpha are late heterochromatin markers in development, but present in undifferentiated embryonic stem cells
[作者：Wongtawan, T; Taylor, JE; Lawson, KA; Wilmut, I; Pennings, S,期刊：Journal of cell science, 页码：1878-1890 , 文章类型： Article，,卷期：2011年124-11]
- We report here that the formation of heterochromatin in cell nuclei during mouse development is characterised by dynamic changes in the epigenetic modifications of histones. Our observations reveal that heterochromatin i...
- Cyclosporin-A-induced prion protein aggresomes are dynamic quality-control cellular compartments
[作者：Ben-Gedalya, T; Lyakhovetsky, R; Yedidia, Y; Bejerano-Sagie, M; Kogan, NM; Karpuj, MV; Kaganovich, D; Cohen, E,期刊：Journal of cell science, 页码：1891-1902 , 文章类型： Article，,卷期：2011年124-11]
- Despite the activity of cellular quality-control mechanisms, subsets of mature and newly synthesized polypeptides fail to fold properly and form insoluble aggregates. In some cases, protein aggregation leads to the devel...
- Single-molecule binding of CD44 to fibrin versus P-selectin predicts their distinct shear-dependent interactions in cancer
[作者：Raman, PS; Alves, CS; Wirtz, D; Konstantopoulos, K,期刊：Journal of cell science, 页码：1903-1910 , 文章类型： Article，,卷期：2011年124-11]
- P-selectin and fibrin(ogen) have pivotal roles in the hematogenous dissemination of tumor cells. CD44 variant isoforms, CD44v, have been identified as the major functional P-selectin ligands and fibrin receptors on metas...
- Romo1 is a negative-feedback regulator of Myc
[作者：Lee, SB; Kim, JJ; Chung, JS; Lee, MS; Lee, KH; Kim, BS; Tansey, WP; Yoo, YD,期刊：Journal of cell science, 页码：1911-1924 , 文章类型： Article，,卷期：2011年124-11]
- Degradation of Myc protein is mediated by E3 ubiquitin ligases, including SCFFbw7 and SCFSkp2, but much remains unknown about the mechanism of S-phase kinase-associated protein (Skp2)-mediated Myc degradation. In the pre...
- IGF binding protein 3 exerts its ligand-independent action by antagonizing BMP in zebrafish embryos
[作者：Zhong, YB; Lu, L; Zhou, JF; Li, Y; Liu, YZ; Clemmons, DR; Duan, CM,期刊：Journal of cell science, 页码：1925-1935 , 文章类型： Article，,卷期：2011年124-11]
- IGFBP3 is a multi-functional protein that has IGF-dependent and IGF-independent actions in cultured cells. Here we show that the IGF binding domain (IBD), nuclear localization signal (NLS) and transactivation domain (TA)...
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