- SEMAGACESTAT gamma-Secretase Inhibitor Treatment of Alzheimer's Disease
[作者:Davies, S; Pandian, R; Bolos, J; Castaner, R,期刊:Drugs of the Future, 页码:613-617 , 文章类型: Article,,卷期:2009年34-8]
- gamma-Secretase has been identified as a therapeutic target for Alzheimer's disease (AD), as it plays a role in the production of beta-amyloid (A beta) peptide, a key component of AD plaques. Lilly is currently developin...
- SOTRASTAURIN Protein Kinase C Inhibitor Treatment of Transplant Rejection Treatment of Psoriasis Treatment of Uveitis
[作者:McCall, M; Merani, S; Toso, C; Shapiro, AMJ,期刊:Drugs of the Future, 页码:618-623 , 文章类型: Article,,卷期:2009年34-8]
- Sotrastaurin (AEB-071, NVP-AEB-071) is an orally bioavailable compound that exerts its effects through the selective inhibition of the classic and novel forms of protein kinase C (PKC), thereby inhibiting early T-cell ac...
- beta(3)-ADRENOCEPTOR AGONISTS FOR THE TREATMENT OF OVERACTIVE BLADDER
[作者:Tyagi, P; Tyagi, V; Yoshimura, N; Chancellor, M; Yamaguchi, O,期刊:Drugs of the Future, 页码:635-640 , 文章类型: Review,,卷期:2009年34-8]
- Overactive bladder (OAB) is a medical condition that refers to the bothersome symptoms of increased frequency of voiding episodes and involuntary urinary urgency, with or without subsequent urinary incontinence and often...
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