- Estrogen induces apoptosis in estrogen deprivation-resistant breast cancer through stress responses as identified by global gene expression across time
[作者:Ariazi, EA; Cunliffe, HE; Lewis-Wambi, JS; Slifker, MJ; Willis, AL; Ramos, P; Tapia, C; Kim, HR; Yerrum, S; Sharma, CGN; Nicolas, E; Balagurunathan, Y; Ross, EA; Jordan, VC,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18879-18886 , 文章类型: Article,,卷期:2011年108-47]
- In laboratory studies, acquired resistance to long-termantihormonal therapy in breast cancer evolves through two phases over 5 y. Phase I develops within 1 y, and tumor growth occurs with either 17 beta-estradiol (E(2)) ...
- Direct-bandgap light-emitting germanium in tensilely strained nanomembranes
[作者:Sanchez-Perez, JR; Boztug, C; Chen, F; Sudradjat, FF; Paskiewicz, DM; Jacobson, RB; Lagally, MG; Paiella, R,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18893-18898 , 文章类型: Article,,卷期:2011年108-47]
- Silicon, germanium, and related alloys, which provide the leading materials platform of electronics, are extremely inefficient light emitters because of the indirect nature of their fundamental energy bandgap. This basic...
- Holocene dynamics of the Arctic's largest ice shelf
[作者:Antoniades, D; Francus, P; Pienitz, R; St-Onge, G; Vincent, WF,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18899-18904 , 文章类型: Article,,卷期:2011年108-47]
- Ice shelves in the Arctic lost more than 90% of their total surface area during the 20th century and are continuing to disintegrate rapidly. The significance of these changes, however, is obscured by the poorly constrain...
- Low paternity skew and the influence of maternal kin in an egalitarian, patrilocal primate
[作者:Strier, KB; Chaves, PB; Mendes, SL; Fagundes, V; Di Fiore, A,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18915-18919 , 文章类型: Article,,卷期:2011年108-47]
- Levels of reproductive skew vary in wild primates living in multimale groups depending on the degree to which high-ranking males monopolize access to females. Still, the factors affecting paternity in egalitarian societi...
- Evolution of D-lactate dehydrogenase activity from glycerol dehydrogenase and its utility for D-lactate production from lignocellulose
[作者:Wang, QZ; Ingram, LO; Shanmugam, KT,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18920-18925 , 文章类型: Article,,卷期:2011年108-47]
- Lactic acid, an attractive, renewable chemical for production of biobased plastics (polylactic acid, PLA), is currently commercially produced from food-based sources of sugar. Pure optical isomers of lactate needed for P...
- Nitrosyl hydride (HNO) replaces dioxygen in nitroxygenase activity of manganese quercetin dioxygenase
[作者:Kumar, MR; Zapata, A; Ramirez, AJ; Bowen, SK; Francisco, WA; Farmer, PJ,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18926-18931 , 文章类型: Article,,卷期:2011年108-47]
- Quercetin dioxygenase (QDO) catalyzes the oxidation of the flavonol quercetin with dioxygen, cleaving the central heterocyclic ring and releasing CO. The QDO from Bacillus subtilis is unusual in that it has been shown to...
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