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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共10条记录   Emerging Applications of Riboswitches in Chemical Biology [作者：TOPP SHANA; GALLIVAN JUSTIN P,期刊：ACS CHEMICAL BIOLOGY, 页码：139-148 , 文章类型： Article，,卷期：2010年5-1] Living systems use RNA sequences known as riboswitches to detect the concentrations of small-molecule metabolites within cells and to regulate the expression of genes that produce these metabolites. Like their natural co... Decoding Signals with Chemical Biology [作者：KIESSLING LAURA L,期刊：ACS CHEMICAL BIOLOGY, 页码：1-2 , 文章类型： Editorial Material，,卷期：2010年5-1] no Exploring Disease through Metabolomics [作者：VINAYAVEKHIN NAWAPORN; HOMAN EDWIN A; SAGHATELIAN ALAN,期刊：ACS CHEMICAL BIOLOGY, 页码：91-103 , 文章类型： Article，,卷期：2010年5-1] Metabolomics approaches provide an analysis of changing metabolite levels in biological samples. in the past decade, technical advances have spurred the application of metabolomics in a variety of diverse research areas ... Controlling Destiny through Chemistry: Small-Molecule Regulators of Cell Fate [作者：FIRESTONE ARI J; CHEN JAMES K,期刊：ACS CHEMICAL BIOLOGY, 页码：15-34 , 文章类型： Review，,卷期：2010年5-1] Controlling cell fate is essential for embryonic development, tissue regeneration, and the prevention of human disease. With each cell in the human body sharing a common genome, achieving the appropriate spectrum of stem... Regulation of Intracellular Signaling by Extracellular Glycan Remodeling [作者：PARKER RANDY B; KOHLER JENNIFER J,期刊：ACS CHEMICAL BIOLOGY, 页码：35-46 , 文章类型： Review，,卷期：2010年5-1] The plasma membrane of eukaryotic cells is coated with carbohydrates. By virtue of their extracellular position and recognizable chemical features, cell surface glycans mediate many receptor-ligand interactions. Recently... Orchestrating Redox Signaling Networks through Regulatory Cysteine Switches [作者：PAULSEN CANDICE E; CARROLL KATE S,期刊：ACS CHEMICAL BIOLOGY, 页码：47-62 , 文章类型： Review，,卷期：2010年5-1] Hydrogen peroxide (H2O2) acts as a second messenger that can mediate intracellular signal transduction via chemoselective oxidation of cysteine residues in signaling proteins. This Review presents current mechanistic ins... Making the Cut: The Chemical Biology of Cytokinesis [作者：ATILLAGOKCUMEN G EKIN; CASTORENO ADAM B; SASSE SOFIA; EGGERT ULRIKE S,期刊：ACS CHEMICAL BIOLOGY, 页码：79-90 , 文章类型： Review，,卷期：2010年5-1] Cytokinesis is the last step in the cell cycle, where daughter cells finally separate. It is precisely regulated in both time and space to ensure that each daughter cell receives an equal share of DNA and other cellular ... Phosphoproteomics for the Masses [作者：GRIMSRUD PAUL A; SWANEY DANIELLE L; WENGER CRAIG D; BEAUCHENE NICOLE A; COON JOSHUA J,期刊：ACS CHEMICAL BIOLOGY, 页码：105-119 , 文章类型： Review，,卷期：2010年5-1] Protein phosphorylation serves as a primary mechanism of signal transduction in the cells of biological organisms. Technical advancements over the last several years in mass spectrometry now allow for the large-scale ide... Biochemical Mechanisms of Resistance to Small-Molecule Protein Kinase Inhibitors [作者：KRISHNAMURTY RATIKA; MALY DUSTIN J,期刊：ACS CHEMICAL BIOLOGY, 页码：121-138 , 文章类型： Review，,卷期：2010年5-1] Protein kinases have emerged as one of the most frequently targeted families of proteins in drug discovery. While the development of small-molecule inhibitors that have the potency and selectivity necessary to be effecti... Jasmonates: Structural Requirements for Lipid-Derived Signals Active in Plant Stress Responses and Development [作者：WASTERNACK CLAUS; KOMBRINK ERICH,期刊：ACS CHEMICAL BIOLOGY, 页码：63-77 , 文章类型： Review，,卷期：2010年5-1] Jasmonates are lipid-derived signals that mediate plant stress responses and development processes. Enzymes participating in biosynthesis of jasmonic acid (JA) (1, 2) and components of JA signaling have been extensively ...