- Consistency Test of the Cell Cycle: Roles for p53 and EGR1
[作者：Zwang, Y; Oren, M; Yarden, Y,期刊：Cancer research, 页码：1051-1054 , 文章类型： Review，,卷期：2012年72-5]
- Mammalian cells are constantly exposed to multiple mitogens and, hence, have developed machineries that help them ignore fortuitous signals. In a recent report in Molecular Cell, we highlighted the molecular details of s...
- Human T(H)17 Immune Cells Specific for the Tumor Antigen MAGE-A3 Convert to IFN-gamma-Secreting Cells as They Differentiate into Effector T Cells In Vivo
[作者：Hamai, A; Pignon, P; Raimbaud, I; Duperrier-Amouriaux, K; Senellart, H; Hiret, S; Douillard, JY; Bennouna, J; Ayyoub, M; Valmori, D,期刊：Cancer research, 页码：1059-1063 , 文章类型： Article，,卷期：2012年72-5]
- The role of T(H)17 cells in cancer is being investigated, but the existence of tumor antigen-specific T(H)17 cells has yet to be ascertained. Here, we report the first description of a spontaneous T(H)17 (IL-17(+)) respo...
- Ovarian Cancer Risk Associated with Inherited Inflammation-Related Variants
[作者：White, KL; Schildkraut, JM; Palmieri, RT; Iversen, ES; Berchuck, A; Vierkant, RA; Rider, DN; Charbonneau, B; Cicek, MS; Sutphen, R; Birrer, MJ; Pharoah, PPD; Song, H; Tyrer, J; Gayther, SA; Ramus, SJ; Wentzensen, N; Yang, HP; Garcia-Closas, M; Phelan, CM; Cunningham, JM; Fridley, BL; Sellers, TA; Goode, EL,期刊：Cancer research, 页码：1064-1069 , 文章类型： Article，,卷期：2012年72-5]
- The importance of inflammation pathways to the development of many human cancers prompted us to examine the associations between single-nucleotide polymorphisms (SNP) in inflammation-related genes and risk of ovarian can...
- Immunotype and Immunohistologic Characteristics of Tumor-Infiltrating Immune Cells Are Associated with Clinical Outcome in Metastatic Melanoma
[作者：Erdag, G; Schaefer, JT; Smolkin, ME; Deacon, DH; Shea, SM; Dengel, LT; Patterson, JW; Slingluff, CL,期刊：Cancer research, 页码：1070-1080 , 文章类型： Article，,卷期：2012年72-5]
- Immune cells infiltrating the microenvironment of melanoma metastases may either limit or promote tumor progression, but the characteristics that distinguish these effects are obscure. In this study, we systematically ev...
- Exploiting the Mutanome for Tumor Vaccination
[作者：Castle, JC; Kreiter, S; Diekmann, J; Lower, M; Van de Roemer, N; de Graaf, J; Selmi, A; Diken, M; Boegel, S; Paret, C; Koslowski, M; Kuhn, AN; Britten, CM; Huber, C; Tuereci, O; Sahin, U,期刊：Cancer research, 页码：1081-1091 , 文章类型： Article，,卷期：2012年72-5]
- Multiple genetic events and subsequent clonal evolution drive carcinogenesis, making disease elimination with single-targeted drugs difficult. The multiplicity of gene mutations derived from clonal heterogeneity therefor...
- Tumor-Derived Chemokine CCL5 Enhances TGF-beta-Mediated Killing of CD8(+) T Cells in Colon Cancer by T-Regulatory Cells
[作者：Chang, LY; Lin, YC; Mahalingam, J; Huang, CT; Chen, TW; Kang, CW; Peng, HM; Chu, YY; Chiang, JM; Dutta, A; Day, YJ; Chen, TC; Yeh, CT; Lin, CY,期刊：Cancer research, 页码：1092-1102 , 文章类型： Article，,卷期：2012年72-5]
- Chemokine CCL5/RANTES is highly expressed in cancer where it contributes to inflammation and malignant progression. In this study, we show that CCL5 plays a critical role in immune escape in colorectal cancer. We found t...
- Effective Treatment of Metastatic Forms of Epstein-Barr Virus-Associated Nasopharyngeal Carcinoma with a Novel Adenovirus-Based Adoptive Immunotherapy
[作者：Smith, C; Tsang, J; Beagley, L; Chua, D; Lee, V; Li, V; Moss, DJ; Coman, W; Chan, KH; Nicholls, J; Kwong, D; Khanna, R,期刊：Cancer research, 页码：1116-1125 , 文章类型： Article，,卷期：2012年72-5]
- Nasopharyngeal carcinoma (NPC) is endemic in China and Southeast Asia where it is tightly associated with infections by Epstein-Barr virus (EBV). The role of tumor-associated viral antigens in NPC renders it an appealing...
- Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors
[作者：Niinuma, T; Suzuki, H; Nojima, M; Nosho, K; Yamamoto, H; Takamaru, H; Yamamoto, E; Maruyama, R; Nobuoka, T; Miyazaki, Y; Nishida, T; Bamba, T; Kanda, T; Ajioka, Y; Taguchi, T; Okahara, S; Takahashi, H; Nishida, Y; Hosokawa, M; Hasegawa, T; Tokino, T; Hirata, K; Imai, K; Toyota, M; Shinomura, Y,期刊：Cancer research, 页码：1126-1136 , 文章类型： Article，,卷期：2012年72-5]
- Large intergenic noncoding RNAs (lincRNA) have been less studied than miRNAs in cancer, although both offer considerable theranostic potential. In this study, we identified frequent upregulation of miR-196a and lincRNA H...
- KR-POK Interacts with p53 and Represses Its Ability to Activate Transcription of p21WAF1/CDKN1A
[作者：Jeon, BN; Kim, MK; Choi, WI; Koh, DI; Hong, SY; Kim, KS; Kim, MJ; Yun, CO; Yoon, J; Choi, KY; Lee, KR; Nephew, KP; Hur, MW,期刊：Cancer research, 页码：1137-1148 , 文章类型： Article，,卷期：2012年72-5]
- Transcriptional regulation by p53 is thought to play a role in its ability to suppress tumorigenesis. However, there remain gaps in understanding about how p53 regulates transcription and how disrupting this function may...
- ATR-ATRIP Kinase Complex Triggers Activation of the Fanconi Anemia DNA Repair Pathway
[作者：Shigechi, T; Tomida, J; Sato, K; Kobayashi, M; Eykelenboom, JK; Pessina, F; Zhang, YB; Uchida, E; Ishiai, M; Lowndes, NF; Yamamoto, K; Kurumizaka, H; Maehara, Y; Takata, M,期刊：Cancer research, 页码：1149-1156 , 文章类型： Article，,卷期：2012年72-5]
- ATR kinase activates the S-phase checkpoint when replication forks stall at sites of DNA damage. This event also causes phosphorylation of the Fanconi anemia (FA) protein FANCI, triggering its monoubiquitination of the k...
- Kaposi Sarcoma Herpesvirus Promotes Endothelial-to-Mesenchymal Transition through Notch-Dependent Signaling
[作者：Gasperini, P; Espigol-Frigole, G; McCormick, PJ; Salvucci, O; Maric, D; Uldrick, TS; Polizzotto, MN; Yarchoan, R; Tosato, G,期刊：Cancer research, 页码：1157-1169 , 文章类型： Article，,卷期：2012年72-5]
- Endothelial-to-mesenchymal transition (EndMT) is now widely considered a pivotal contributor to cancer progression. In this study, we show that the Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) is a sufficient caus...
- DNA Methylation Does Not Stably Lock Gene Expression but Instead Serves as a Molecular Mark for Gene Silencing Memory
[作者：Raynal, NJM; Si, J; Taby, RF; Gharibyan, V; Ahmed, S; Jelinek, J; Estecio, MRH; Issa, JPJ,期刊：Cancer research, 页码：1170-1181 , 文章类型： Article，,卷期：2012年72-5]
- DNA methylation is commonly thought of as a "molecular lock" that leads to permanent gene silencing. To investigate this notion, we tested 24 different histone deacetylase inhibitors (HDACi) on colon cancer cells that ha...
- Novel Genetic Markers of Breast Cancer Survival Identified by a Genome-Wide Association Study
[作者：Shu, XO; Long, JR; Lu, W; Li, C; Chen, WY; Delahanty, R; Cheng, J; Cai, H; Zheng, Y; Shi, JJ; Gu, K; Wang, WJ; Kraft, P; Gao, YT; Cai, QY; Zheng, W,期刊：Cancer research, 页码：1182-1189 , 文章类型： Article，,卷期：2012年72-5]
- Only two genome-wide association studies (GWAS) have been conducted to date to identify potential markers for total mortality after diagnosis of breast cancer. Here, we report the identification of two single-nucleotide ...
- Impact of Circulating Vitamin D Binding Protein Levels on the Association between 25-Hydroxyvitamin D and Pancreatic Cancer Risk: A Nested Case-Control Study
[作者：Weinstein, SJ; Stolzenberg-Solomon, RZ; Kopp, W; Rager, H; Virtamo, J; Albanes, D,期刊：Cancer research, 页码：1190-1198 , 文章类型： Article，,卷期：2012年72-5]
- High concentrations of circulating 25-hydroxyvitamin D [25(OH)D] have been associated with elevated pancreatic cancer risk. As this is contrary to an expected inverse association between vitamin D status and cancer, we e...
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