- First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children
[作者:Agnandji, ST; Lell, B; Soulanoudjingar, SS; Fernandes, JF; Abossolo, BP; Conzelmann, C; Methogo, BGNO; Doucka, Y; Flamen, A; Mordmuller, B; Issifou, S; Kremsner, PG; Sacarlal, J; Aide, P; Lanaspa, M; Aponte, JJ; Nhamuave, A; Quelhas, D; Bassat, Q; Mandjate, S; Macete, E; Alonso, P; Abdulla, S; Salim, N; Juma, O; Shomari, M; Shubis, K; Machera, F; Hamad, AS; Minja, R; Mpina, M; Mtoro, A; Sykes, A; Ahmed, S; Urassa, AM; Ali, AM; Mwangoka, G; Tanner, M; Tinto, H; D'Alessandro, U; Sorgho, H; Valea, I; Tahita, MC; Kabore, W; Ouedraogo, S; Sandrine, Y; Guiguemde, RT; Ouedraogo, JB; Hamel, MJ; Kariuki, S; Odero, C; Oneko, M; Otieno, K; Awino, N; Omoto, J; Williamson, J; Muturi-Kioi, V; Laserson, KF; Slutsker, L; Otieno, W; Otieno, L; Nekoye, O; Gondi, S; Otieno, A; Ogutu, B; Wasuna, R; Owira, V; Jones, D; Onyango, AA; Njuguna, P; Chilengi, R; Akoo, P; Kerubo, C; Gitaka, J; Maingi, C; Lang, T; Olotu, A; Tsofa, B; Bejon, P; Peshu, N; Marsh, K; Owusu-Agyei, S; Asante, KP; Osei-Kwakye, K; Boahen,,期刊:New England Journal of Medicine, 页码:1863-1875 , 文章类型: Article,,卷期:2011年365-20]
- BACKGROUNDAn ongoing phase 3 study of the efficacy, safety, and immunogenicity of candidate malaria vaccine RTS,S/AS01 is being conducted in seven African countries.METHODSFrom March 2009 through January 2011, we enrolle...
- Childhood Adiposity, Adult Adiposity, and Cardiovascular Risk Factors
[作者:Juonala, M; Magnussen, CG; Berenson, GS; Venn, A; Burns, TL; Sabin, MA; Srinivasan, SR; Daniels, SR; Davis, PH; Chen, W; Sun, C; Cheung, M; Viikari, JSA; Dwyer, T; Raitakari, OT,期刊:New England Journal of Medicine, 页码:1876-1885 , 文章类型: Article,,卷期:2011年365-20]
- BACKGROUNDObesity in childhood is associated with increased cardiovascular risk. It is uncertain whether this risk is attenuated in persons who are overweight or obese as children but not obese as adults.METHODSWe analyz...
- Mycophenolate versus Azathioprine as Maintenance Therapy for Lupus Nephritis
[作者:Dooley, MA; Jayne, D; Ginzler, EM; Isenberg, D; Olsen, NJ; Wofsy, D; Eitner, F; Appel, GB; Contreras, G; Lisk, L; Solomons, N,期刊:New England Journal of Medicine, 页码:1886-1895 , 文章类型: Article,,卷期:2011年365-20]
- BACKGROUNDMaintenance therapy, often with azathioprine or mycophenolate mofetil, is required to consolidate remission and prevent relapse after the initial control of lupus nephritis.METHODSWe carried out a 36-month, ran...
- ADHD Drugs and Serious Cardiovascular Events in Children and Young Adults
[作者:Cooper, WO; Habel, LA; Sox, CM; Chan, KA; Arbogast, PG; Cheetham, TC; Murray, KT; Quinn, VP; Stein, CM; Callahan, ST; Fireman, BH; Fish, FA; Kirshner, HS; O'Duffy, A; Connell, FA; Ray, WA,期刊:New England Journal of Medicine, 页码:1896-1904 , 文章类型: Article,,卷期:2011年365-20]
- BACKGROUNDAdverse-event reports from North America have raised concern that the use of drugs for attention deficit-hyperactivity disorder (ADHD) increases the risk of serious cardiovascular events.METHODSWe conducted a r...
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