- Cisplatin increases B-cell-lymphoma-2 expression via activation of protein kinase C and Akt2 in endometrial cancer cells
[作者:Rouette, A; Parent, S; Girouard, J; Leblanc, V; Asselin, E,期刊:International Journal of Cancer, 页码:1755-1767 , 文章类型: Article,,卷期:2012年130-8]
- Human carcinomas often show resistance to cisplatin and Bcl-2 is associated with resistance to cisplatin. However, Bcl-2 regulation on cisplatin treatment in human cancers is unknown. Here, we show a novel mechanism by w...
- MUC4: a novel prognostic factor of oral squamous cell carcinoma
[作者:Hamada, T; Wakamatsu, T; Miyahara, M; Nagata, S; Nomura, M; Kamikawa, Y; Yamada, N; Batra, SK; Yonezawa, S; Sugihara, K,期刊:International Journal of Cancer, 页码:1768-1776 , 文章类型: Article,,卷期:2012年130-8]
- MUC4 mucin is now known to be expressed in various normal and cancer tissues. We have previously reported that MUC4 expression is a novel prognostic factor in several malignant tumors; however, it has not been investigat...
- Expression and pharmacological inhibition of thymidylate synthase and Src kinase in nonsmall cell lung cancer
[作者:Ceppi, P; Rapa, I; Lo Iacono, M; Righi, L; Giorcelli, J; Pautasso, M; Bille, A; Ardissone, F; Papotti, M; Scagliotti, GV,期刊:International Journal of Cancer, 页码:1777-1786 , 文章类型: Article,,卷期:2012年130-8]
- The combination of cytotoxic chemotherapy with signaling pathway inhibitors represents a potential strategy to improve the treatment of nonsmall cell lung cancer (NSCLC). Thymidylate synthase (TS) is an enzyme essential ...
- Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1
[作者:Boyerinas, B; Park, SM; Murmann, AE; Gwin, K; Montag, AG; Zillhardt, M; Hua, YJ; Lengyel, E; Peter, ME,期刊:International Journal of Cancer, 页码:1787-1797 , 文章类型: Article,,卷期:2012年130-8]
- Ovarian cancer patients frequently develop resistance to chemotherapy regiments using Taxol and carboplatin. One of the resistance factors that protects cancer cells from Taxol-based therapy is multidrug resistance 1 (MD...
- The neurotensin receptor-1 promotes tumor development in a sporadic but not an inflammation-associated mouse model of colon cancer
[作者:Bugni, JM; Al-Rabadi, L; Jubbal, K; Karagiannides, I; Lawson, G; Pothoulakis, C,期刊:International Journal of Cancer, 页码:1798-1805 , 文章类型: Article,,卷期:2012年130-8]
- Neurotensin receptor-1 (NTR-1) is overexpressed in colon cancers and colon cancer cell lines. Signaling through this receptor stimulates proliferation of colonocyte-derived cell lines and promotes inflammation and mucosa...
- Human papillomavirus status in young patients with head and neck squamous cell carcinoma
[作者:van Monsjou, HS; van Velthuysen, MLF; van den Brekel, MWM; Jordanova, ES; Melief, CJM; Balm, AJM,期刊:International Journal of Cancer, 页码:1806-1812 , 文章类型: Article,,卷期:2012年130-8]
- The role of human papillomavirus (HPV) in head and neck squamous cell carcinoma (HNSCC) development has been recognized only in the last decade. Although younger patients develop HNSCC associated with HPV, the incidence ...
- T cells raised against allogeneic HLA-A2/CD20 kill primary follicular lymphoma and acute lymphoblastic leukemia cells
[作者:Abrahamsen, IW; Kjellevoll, S; Greve-Isdahl, M; Mensali, N; Walchli, S; Kumari, S; Loland, BF; Egeland, T; Kolstad, A; Olweus, J,期刊:International Journal of Cancer, 页码:1821-1832 , 文章类型: Article,,卷期:2012年130-8]
- T cells mediating a graft-versus-leukemia/lymphoma effects without causing graft-versus-host disease would greatly improve the safety and applicability of hematopoietic stem cell transplantation. We recently demonstrated...
- Lymph node CEA and MUC2 mRNA as useful predictors of outcome in colorectal cancer
[作者:Ohlsson, L; Israelsson, A; Oberg, A; Palmqvist, R; Stenlund, H; Hammarstrom, ML; Hammarstrom, S; Lindmark, G,期刊:International Journal of Cancer, 页码:1833-1843 , 文章类型: Article,,卷期:2012年130-8]
- The aim was to explore the utility for staging and prognostic impact of carcinoembryonic antigen (CEA), cytokeratin 20 (CK20), guanylyl cyclase C (GCC), CUB (complement protein subcomponents C1r/C1s, urchin embryonic gro...
- Improved sensitivity of vaginal self-collection and high-risk human papillomavirus testing
[作者:Belinson, JL; Du, H; Yang, B; Wu, RF; Belinson, SE; Qu, XF; Pretorius, RG; Yi, X; Castle, PE,期刊:International Journal of Cancer, 页码:1855-1860 , 文章类型: Article,,卷期:2012年130-8]
- Self-collected vaginal specimens tested for high-risk human papillomavirus (HR-HPV) have been shown to be less sensitive for the detection of cervical intraepithelial neoplasia or cancer (>= CIN 3) than physician-collect...
- A four-gene methylation marker panel as triage test in high-risk human papillomavirus positive patients
[作者:Eijsink, JJH; Lendvai, A; Deregowski, V; Klip, HG; Verpooten, G; Dehaspe, L; de Bock, GH; Hollema, H; van Criekinge, W; Schuuring, E; van der Zee, AGJ; Wisman, GBA,期刊:International Journal of Cancer, 页码:1861-1869 , 文章类型: Article,,卷期:2012年130-8]
- Cervical neoplasia-specific biomarkers, e.g. DNA methylation markers, with high sensitivity and specificity are urgently needed to improve current population-based screening on (pre)malignant cervical neoplasia. We aimed...
- Switch from cytology-based to human papillomavirus test-based cervical screening: implications for colposcopy
[作者:Porras, C; Wentzensen, N; Rodriguez, AC; Morales, J; Burk, RD; Alfaro, M; Hutchinson, M; Herrero, R; Hildesheim, A; Sherman, ME; Wacholder, S; Solomon, D; Schiffman, M,期刊:International Journal of Cancer, 页码:1879-1887 , 文章类型: Article,,卷期:2012年130-8]
- Human papillomavirus (HPV) testing is more sensitive than cytology; some cervical cancer prevention programs will switch from cytology to carcinogenic HPV test-based screening. The objective of our study is to evaluate t...
- Male circumcision is associated with a lower prevalence of human papillomavirus-associated penile lesions among Kenyan men
[作者:Backes, DM; Bleeker, MCG; Meijer, CJLM; Hudgens, MG; Agot, K; Bailey, RC; Ndinya-Achola, JO; Hayombe, J; Hogewoning, CJA; Moses, S; Snijders, PJF; Smith, JS,期刊:International Journal of Cancer, 页码:1888-1897 , 文章类型: Article,,卷期:2012年130-8]
- Human papillomavirus (HPV)-associated penile lesions in men may increase the risk of HPV transmission to their female partners. Risk factor data on HPV-associated penile lesions are needed from regions with a high burden...
- Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk
[作者:Wang, J; Joshi, AD; Corral, R; Siegmund, KD; Le Marchand, L; Martinez, ME; Haile, RW; Ahnen, DJ; Sandler, RS; Lance, P; Stern, MC,期刊:International Journal of Cancer, 页码:1898-1907 , 文章类型: Article,,卷期:2012年130-8]
- Diets high in red meat are established risk factors for colorectal cancer (CRC). Carcinogenic compounds generated during meat cooking have been implicated as causal agents. We conducted a family-based case-control study ...
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