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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共9条记录   Clinical, phenotypic and genetic similarities and disparities between post-transplant and classical Hodgkin lymphomas with respect to therapeutic targets [作者：Adams, H; Campidelli, C; Dirnhofer, S; Pileri, SA; Tzankov, A,期刊：Expert Opinion on Therapeutic Targets, 页码：1137-1145 , 文章类型： Article，,卷期：2009年13-10] Objective: Post-transplant Hodgkin lymphoma (ptHL) is a rare but serious complication. We explored the clinical, phenotypic and genetic similarities and disparities between ptHL and classical Hodgkin lymphoma (cHL) in im... Targeting the CXCR4/CXCL12 axis in systemic lupus erythematosus [作者：Chong, BF; Mohan, C,期刊：Expert Opinion on Therapeutic Targets, 页码：1147-1153 , 文章类型： Review，,卷期：2009年13-10] Background: CXCR4 antagonists have garnered much interest as promising treatments for cancer metastases and HIV. Given its ability to attract multiple leukocyte subsets and stimulate B cell production and myelopoeisis, r... Targeting the JAK2/STAT3 axis in Alzheimer's disease [作者：Chiba, T; Yamada, M; Aiso, S,期刊：Expert Opinion on Therapeutic Targets, 页码：1155-1167 , 文章类型： Review，,卷期：2009年13-10] Background: Amyloid P (A beta) has long been implicated in the pathogenesis of Alzheimer's disease (AD). Little is known, however, about the intracellular events in neurons which lead to memory loss related to AD. Focusi... TrkB as a therapeutic target for ovarian cancer [作者：Siu, MKY; Wong, OGW; Cheung, ANY,期刊：Expert Opinion on Therapeutic Targets, 页码：1169-1178 , 文章类型： Review，,卷期：2009年13-10] Background: In many countries, ovarian cancer is the most lethal gynecological malignancy. Its poor prognosis is mainly due to the late stage of disease with metastasis at presentation. The significant failure rate of ch... Targeting the IGF1 axis in cancer proliferation [作者：Bruchim, I; Attias, Z; Werner, H,期刊：Expert Opinion on Therapeutic Targets, 页码：1179-1192 , 文章类型： Review，,卷期：2009年13-10] The IGF network of ligands, cell-surface receptors and IGF-binding proteins has important roles at multiple levels, including the cellular, organ and organism levels. The IGF system mediates growth, differentiation and d... Enhancing mTOR-targeted cancer therapy [作者：Wang, XR; Sun, SY,期刊：Expert Opinion on Therapeutic Targets, 页码：1193-1203 , 文章类型： Review，,卷期：2009年13-10] Background: The mammalian target of rapamycin (mTOR) has emerged as an attractive cancer therapeutic target. Accordingly, several mTOR inhibitors (e.g., rapamycin and its analogs; rapalogs) are currently being tested in ... Targeting insulin sensitivity in the treatment of polycystic ovary syndrome [作者：Pasquali, R; Gambineri, A,期刊：Expert Opinion on Therapeutic Targets, 页码：1205-1226 , 文章类型： Review，,卷期：2009年13-10] Targeting insulin resistance may result in a list of benefits for women with PCOS, including hormonal, metabolic and ovulatory (and fertility) improvements. The therapeutic strategy to treat PCOS should however depend on... Targeting microRNAs in obesity [作者：Xie, HM; Sun, L; Lodish, HF,期刊：Expert Opinion on Therapeutic Targets, 页码：1227-1238 , 文章类型： Review，,卷期：2009年13-10] Obesity is a serious health problem worldwide associated with an increased risk of life-threatening diseases such as type 2 diabetes, atherosclerosis, and certain types of cancer. Fundamental for the development of novel... RPGR and RP2: targets for the treatment of X-linked retinitis pigmentosa? [作者：Veltel, S; Wittinghofer, A,期刊：Expert Opinion on Therapeutic Targets, 页码：1239-1251 , 文章类型： Review，,卷期：2009年13-10] Retinitis pigmentosa is the most important hereditary eye disease and there is currently no cure available. Although mutations were found in more than 40 genes in patients with retinitis pigmentosa, only two genes have t...