- Rescue of Bacteriophage T7 DNA Polymerase of Low Processivity by Suppressor Mutations Affecting Gene 3 Endonuclease
[作者:Lee, SJ; Chowdhury, K; Tabor, S; Richardson, CC,期刊:Journal of virology, 页码:8418-8427 , 文章类型: Article,,卷期:2009年83-17]
- The DNA polymerase encoded by gene 5 (gp5) of bacteriophage T7 has low processivity, dissociating after the incorporation of a few nucleotides. Upon binding to its processivity factor, Escherichia coli thioredoxin (Trx),...
- A Novel Genotype H9N2 Influenza Virus Possessing Human H5N1 Internal Genomes Has Been Circulating in Poultry in Eastern China since 1998
[作者:Zhang, PH; Tang, YH; Liu, XW; Liu, WB; Zhang, XR; Liu, HQ; Peng, DX; Gao, S; Wu, YT; Zhang, LY; Lu, S; Liu, XF,期刊:Journal of virology, 页码:8428-8438 , 文章类型: Article,,卷期:2009年83-17]
- Many novel reassortant influenza viruses of the H9N2 genotype have emerged in aquatic birds in southern China since their initial isolation in this region in 1994. However, the genesis and evolution of H9N2 viruses in po...
- Mixed Infection and the Genesis of Influenza Virus Diversity
[作者:Ghedin, E; Fitch, A; Boyne, A; Griesemer, S; DePasse, J; Bera, J; Zhang, X; Halpin, RA; Smit, M; Jennings, L; St George, K; Holmes, EC; Spiro, DJ,期刊:Journal of virology, 页码:8832-8841 , 文章类型: Article,,卷期:2009年83-17]
- The emergence of viral infections with potentially devastating consequences for human health is highly dependent on their underlying evolutionary dynamics. One likely scenario for an avian influenza virus, such as A/H5N1...
- Bluetongue Virus VP6 Acts Early in the Replication Cycle and Can Form the Basis of Chimeric Virus Formation
[作者:Matsuo, E; Roy, P,期刊:Journal of virology, 页码:8842-8848 , 文章类型: Article,,卷期:2009年83-17]
- A minor core protein, VP6, of bluetongue virus (BTV) possesses nucleoside triphosphatase, RNA binding, and helicase activities. Although the enzymatic functions of VP6 have been documented in vitro using purified protein...
- A Conformational Switch in Human Immunodeficiency Virus gp41 Revealed by the Structures of Overlapping Epitopes Recognized by Neutralizing Antibodies
[作者:Pejchal, R; Gach, JS; Brunel, FM; Cardoso, RM; Stanfield, RL; Dawson, PE; Burton, DR; Zwick, MB; Wilson, IA,期刊:Journal of virology, 页码:8451-8462 , 文章类型: Article,,卷期:2009年83-17]
- The membrane-proximal external region (MPER) of the human immunodeficiency virus (HIV) envelope glycoprotein (gp41) is critical for viral fusion and infectivity and is the target of three of the five known broadly neutra...
- Kaposi's Sarcoma-Associated Herpesvirus Protein LANA2 Disrupts PML Oncogenic Domains and Inhibits PML-Mediated Transcriptional Repression of the Survivin Gene
[作者:Marcos-Villar, L; Lopitz-Otsoa, F; Gallego, P; Munoz-Fontela, C; Gonzalez-Santamaria, J; Campagna, M; Shou-Jiang, G; Rodriguez, MS; Rivas, C,期刊:Journal of virology, 页码:8849-8858 , 文章类型: Article,,卷期:2009年83-17]
- Infection by herpesviruses causes a dramatic disturbance of PML oncogenic domains (PODs) that has been suggested to be essential for viral lytic replication. Several proteins from Kaposi's sarcoma-associated herpesvirus ...
- The CREB Site in the Proximal Enhancer Is Critical for Cooperative Interaction with the Other Transcription Factor Binding Sites To Enhance Transcription of the Major Intermediate-Early Genes in Human Cytomegalovirus-Infected Cells
[作者:Lashmit, P; Wang, SH; Li, HM; Isomura, H; Stinski, MF,期刊:Journal of virology, 页码:8893-8904 , 文章类型: Article,,卷期:2009年83-17]
- One of the two SP1 sites in the proximal enhancer of the human cytomegalovirus ( HCMV) major immediate-early (MIE) promoter is essential for transcription in human fibroblast cells (H. Isomura, M. F. Stinski, A. Kudoh, T...
- Analysis of Human Immunodeficiency Virus Type 1 Viremia and Provirus in Resting CD4(+) T Cells Reveals a Novel Source of Residual Viremia in Patients on Antiretroviral Therapy
[作者:Brennan, TP; Woods, JO; Sedaghat, AR; Siliciano, JD; Siliciano, RF; Wilke, CO,期刊:Journal of virology, 页码:8470-8481 , 文章类型: Article,,卷期:2009年83-17]
- Highly active antiretroviral therapy (HAART) can reduce human immunodeficiency virus type 1 (HIV-1) viremia to clinically undetectable levels. Despite this dramatic reduction, some virus is present in the blood. In addit...
- Positive Selection Pressure Introduces Secondary Mutations at Gag Cleavage Sites in Human Immunodeficiency Virus Type 1 Harboring Major Protease Resistance Mutations
[作者:Banke, S; Lillemark, MR; Gerstoft, J; Obel, N; Jorgensen, LB,期刊:Journal of virology, 页码:8916-8924 , 文章类型: Article,,卷期:2009年83-17]
- Human immunodeficiency virus type 1 (HIV-1) protease inhibitors (PIs) specifically target the HIV-1 protease enzyme. Mutations in the enzyme can result in PI resistance (termed PI mutations); however, mutations in the HI...
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