- Human Immunodeficiency Virus Type 1 Is Trapped by Acidic but Not by Neutralized Human Cervicovaginal Mucus
[作者:Lai, SK; Hida, K; Shukair, S; Wang, YY; Figueiredo, A; Cone, R; Hope, TJ; Hanes, J,期刊:Journal of virology, 页码:11196-11200 , 文章类型: Article,,卷期:2009年83-21]
- To reliably infect a primate model for human immunodeficiency virus (HIV), similar to 10,000-fold more virus must be delivered vaginally than intravenously. However, the vaginal mechanisms that help protect against HIV a...
- Random Mutagenesis Defines a Domain of Theiler's Virus Leader Protein That Is Essential for Antagonism of Nucleocytoplasmic Trafficking and Cytokine Gene Expression
[作者:Ricour, C; Borghese, F; Sorgeloos, F; Hato, SV; van Kuppeveld, FJM; Michiels, T,期刊:Journal of virology, 页码:11223-11232 , 文章类型: Article,,卷期:2009年83-21]
- The leader protein of cardioviruses, Theiler's murine encephalomyelitis virus (TMEV) and encephalomyocarditis virus (EMCV), is a multifunctional protein known to antagonize type I interferon expression and to interfere w...
- Gene Mapping and Phylogenetic Analysis of the Complete Genome from 30 Single-Stranded RNA Male-Specific Coliphages (Family Leviviridae)
[作者:Friedman, SD; Genthner, FJ; Gentry, J; Sobsey, MD; Vinje, J,期刊:Journal of virology, 页码:11233-11243 , 文章类型: Article,,卷期:2009年83-21]
- Male-specific single-stranded RNA (FRNA) coliphages belong to the family Leviviridae. They are classified into two genera (Levivirus and Allolevivirus), which can be subdivided into four genogroups (genogroups I and II i...
- Broad Neutralization of Human Immunodeficiency Virus Type 1 Mediated by Plasma Antibodies against the gp41 Membrane Proximal External Region
[作者:Gray, ES; Madiga, MC; Moore, PL; Mlisana, K; Karim, SSA; Binley, JM; Shaw, GM; Mascola, JR; Morris, L,期刊:Journal of virology, 页码:11265-11274 , 文章类型: Article,,卷期:2009年83-21]
- We identified three cross-neutralizing plasma samples with high-titer anti-membrane proximal external region (MPER) peptide binding antibodies from among 156 chronically human immunodeficiency virus type 1-infected indiv...
- Identification of Amino Acid Residues Critical for the Anti-Interferon Activity of the Nucleoprotein of the Prototypic Arenavirus Lymphocytic Choriomeningitis Virus
[作者:Martinez-Sobrido, L; Emonet, S; Giannakas, P; Cubitt, B; Garcia-Sastre, A; de la Torre, JC,期刊:Journal of virology, 页码:11330-11340 , 文章类型: Article,,卷期:2009年83-21]
- Lymphocytic choriomeningitis virus (LCVM) nucleoprotein (NP) counteracts the host type I interferon (IFN) response by inhibiting activation of the IFN regulatory factor 3 (IRF3). In this study, we have mapped the regions...
- Novel Avian Bornavirus in a Nonpsittacine Species (Canary; Serinus canaria) with Enteric Ganglioneuritis and Encephalitis
[作者:Weissenbock, H; Sekulin, K; Bakonyi, T; Hogler, S; Nowotny, N,期刊:Journal of virology, 页码:11367-11371 , 文章类型: Article,,卷期:2009年83-21]
- A canary bird (Serinus canaria) died with nonsuppurative ganglioneuritis of the proventriculus and gizzard and encephalitis, lesions comparable to proventricular dilatation disease (PDD) of psittacine birds. Recently, se...
- VP5*Rearranges when Rotavirus Uncoats
[作者:Yoder, JD; Trask, SD; Vo, PT; Binka, M; Feng, N; Harrison, SC; Greenberg, HB; Dormitzer, PR,期刊:Journal of virology, 页码:11372-11377 , 文章类型: Article,,卷期:2009年83-21]
- Trypsin primes rotavirus for efficient infectivity by cleaving the spike protein, VP4, into VP8* and VP5*. A recombinant VP5* fragment has a trimeric, folded-back structure. Comparison of this structure with virion spike...
- Rhesus Theta-Defensin Prevents Death in a Mouse Model of Severe Acute Respiratory Syndrome Coronavirus Pulmonary Disease
[作者:Wohlford-Lenane, CL; Meyerholz, DK; Perlman, S; Zhou, HX; Tran, D; Selsted, ME; McCray, PB,期刊:Journal of virology, 页码:11385-11390 , 文章类型: Article,,卷期:2009年83-21]
- We evaluated the efficacy of rhesus theta-defensin 1 (RTD-1), a novel cyclic antimicrobial peptide, as a prophylactic antiviral in a mouse model of severe acute respiratory syndrome (SARS) coronavirus (CoV) lung disease....
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